The Effect of Body Composition on Respiratory Parameters, Functional Capacity and Sleep in Healthy Young Adults

Body composition has a significant effect on the respiratory system. Both respiratory prediction of function and a prognostic tool evaluated in the cardiopulmonary system factor. Respiratory function, which directly affects respiratory muscle strength and respiratory muscle endurance covers a range of data. In the literature, the relationship between body composition and respiratory function. Although there are studies examining body composition in healthy young adults, the relationship between them has not been clearly demonstrated.

The aim of the study was to investigate the effects of body composition on respiratory function, respiratory muscle endurance, functional capacity and sleep quality.

For this purpose, at least 46 healthy young participants who fulfil the inclusion criteria will participate in the evaluation. Body composition parameters will be measured by the researchers using Tanita DC360 Body Analysis Scale. In pulmonary function test, forced vital capacity (FVC), forced expiratory volume in 1st second (FEV1), Tiffeneau ratio (FEV1/FVC), peak expiratory flow rate (PEF) values will be evaluated by the researchers with COSMED Pony FX (COSMED; Italy) spirometer and respiratory muscle endurance with Maximum Voluntary Ventilation test. Participants will answer the Pittsburg Sleep Quality Index. The 6-minute walk test will be applied to the participants with the instructions of the researchers.

Data will be analysed by SPSS Statistical Package for Social Sciences (SPSS) Version 20.0 (SPSS Inc., Chicago, Illinois) programme will be made using.

Study Overview

• Status: Completed
• Conditions: Healthy; Body Weight
• Intervention / Treatment: Other: The Effect of Body Composition on Respiratory Parameters, Functional Capacity and Sleep in Healthy Young Adults

Detailed Description

Body composition is an important determinant of health and can be used in the assessment of cardiopulmonary problems. Body mass index (BMI) in cardiopulmonary function is an independent prognostic factor. Fat and lean mass have also been identified as strong predictors of physical fitness and mortality.

Pulmonary function is a long-term determinant of all-cause mortality, particularly cardiovascular mortality. Pulmonary function may be affected by malnutrition, recurrent.

It may be influenced by various genetic or environmental factors such as infections and exposure to toxic substances, obesity and systemic diseases.Pulmonary function testing is one of the basic and essential tests for the diagnosis and evaluation of lung diseases such as lung dysfunction, chronic obstructive pulmonary disease (COPD) and asthma. Factors affecting pulmonary function include age, body weight and height, and gender. Since these factors are significantly related to pulmonary function, they are used to calculate the regression equation and predicted normal values of the pulmonary function test.

The correlation between body mass index (BMI), waist size, fat mass and pulmonary function has been studied since the late 1950s. However, the correlation between pulmonary function and body The study results of the correlation between body composition and respiratory function were found to be different from each other. In addition, the mechanism by which body composition affects respiratory function is not fully understood.

Obesity and thus abdominal adiposity also affect aerobic capacity, respiratory function and respiratory muscle strength. Fat accumulation on the chest and abdominal walls inhibits the movement of the respiratory muscles, increases pleural pressure and reduces lung compliance, resulting in a decrease in the compliance of the respiratory system as a whole. Due to all these causes, decreases in functional residual capacity, expiratory reserve volume, forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and respiratory muscle strength are observed.

Strength and endurance tests are recommended to determine decreases in respiratory muscle performance.

Although the number of studies examining the relationship between respiratory muscle strength and body composition is higher in the literature, it has been shown that endurance assessment is more functionally meaningful because inspiratory muscles are used at submaximal level in daily life activities.

Sleep quality is associated with many factors such as age, gender, genetic and environmental factors, social life, economic status, stress, pain, substance abuse, physical diseases, physical activity level, eating habits and obesity.

In the literature, there are many studies examining the relationship between obesity and sleep quality using body composition parameters such as Body Mass Index (BMI), waist circumference, waist-to-hip ratio, and body fat percentage. In some of these studies, it has been suggested that there is no relationship between obesity and sleep quality; in others, it has been shown that obesity is associated with sleep problems, this relationship can be explained by a bidirectional mechanism, sleep problems such as poor sleep quality lead to obesity due to abnormal changes in metabolic and endocrine functions, and obesity leads to various pathological conditions associated with respiration. Obstructive sleep apnoea and obesity hypoventilation syndrome are among these conditions. Therefore, body composition has a significant effect on sleep quality and thus respiratory parameters.

In the literature, there are studies examining the relationship between body composition and respiratory function and respiratory muscle strength in healthy young adults. However, there is no study in the literature investigating the relationship between body composition and respiratory muscle endurance, functional capacity, respiratory function and sleep quality. The aim of study was to investigate the effect of body composition on respiratory function, respiratory muscle strength, respiratory muscle endurance and functional capacity in healthy young adults.

• Study Type: Observational
• Enrollment (Actual): 59

Contacts and Locations

Study Locations

• Turkey
  • Kagıthane-Istanbul
    • Istanbul, Kagıthane-Istanbul, Turkey, 34413
      • Istanbul Kent University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Volunteer young adults between the ages of 18-30 who are willing to participate in the study

Description

Inclusion Criteria:

• Volunteer young adults between the ages of 18-30 who are willing to participate in the study
• Providing independent ambulation
• Individuals without cognitive/mental problems

Exclusion Criteria:

• Lack of co-operation
• Presence of diseases affecting the cardiac and pulmonary system
• Those with a history of neurological, rheumatic or metabolic diseases
• Pregnant women
• Presence of major musculoskeletal problems
• Individuals who smoke

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

Intervention / Treatment

Healthy young adults aged 18-30 years; Sociodemographic information of all participants will be obtained within the scope of the evaluations. Body composition parameters will be measured with Tanita DC360 Body Analysis Scale. In pulmonary function test, Forced vital capacity (FVC), Forced expiratory volume in 1st second (FEV1), Tiffeneau ratio (FEV1/FVC), peak expiratory flow rate (PEF) values will be evaluated with COSMED Pony FX (COSMED; Italy) spirometer. Respiratory muscle endurance will be assessed by Maximum Minute Ventilation will be determined. Pittsburg Sleep Quality, a reliable questionnaire that assesses sleep quality The index will be filled in by the participants. 6 Minutes to assess functional capacity A walking test will be performed and the distance travelled by individuals will be recorded.

Other: The Effect of Body Composition on Respiratory Parameters, Functional Capacity and Sleep in Healthy Young Adults; Sociodemographic information of all participants will be obtained within the scope of the evaluations. Body composition parameters will be measured with Tanita DC360 Body Analysis Scale. In pulmonary function test, Forced vital capacity (FVC), Forced expiratory volume in 1st second (FEV1), Tiffeneau ratio (FEV1/FVC), peak expiratory flow rate (PEF) values will be evaluated with COSMED Pony FX (COSMED; Italy) spirometer. Respiratory muscle endurance will be assessed by Maximum Minute Ventilation will be determined. Pittsburg Sleep Quality, a reliable questionnaire that assesses sleep quality The index will be filled in by the participants. 6 Minutes to assess functional capacity A walking test will be performed and the distance travelled by individuals will be recorded

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Body composition	The body analyses of the participants were performed by the bioelectrical impedance analysis technique by the researchers using "Tanita DC 360 Body Analyser Scale". Body mass index (kg/m2), muscle mass (kg), bone mass (kg) will be recorded by the researchers.	10 minute
Respiratory parameters	Pulmonary function test is a test used to evaluate respiratory parameters.Pulmonary function test was planned by COSMED Pony FX in accordance with the American Thoracic Society and European Respiratory Society criteria. Forced vital capacity, forced expiratory volume in 1st second , Tiffeneau ratio (FEV1/FVC), peak expiratory flow rate values and percentage of predictive values will be recorded by the investigators. Maximum Voluntary Ventilation test will be applied by the researchers to determine the respiratory muscle endurance of the participants.	10 minute

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Functional Capacity	The 6-minute walk test is a test that determines functional capacity. Participants will walk along a 30 metre straight corridor for 6 minutes.The distance covered by walking as fast as possible without running will be recorded by the investigators in metres.	6 minute
Pittsburg Sleep Quality Indeks	Pittsburg Sleep Quality Index developed is a questionnaire that evaluates sleep quality. It will be used to evaluate the sleep quality of the participants. The scale consists of 24 questions in total. Sleep duration, subjective sleep quality, time to fall asleep, effectiveness of habitual sleep, presence of sleep disorders, use of medication to fall asleep and daytime sleep dysfunction. Each item of the scale is evaluated between 0-3 points; the sum of the scores of the seven subcomponents gives the total score of the scale. The lowest score that can be obtained from the scale is 0 and the highest score is 21. A total score greater than 5 indicates that the sleep quality of the individual is not good.	5 minute

Collaborators and Investigators

• Sponsor: Istanbul Kent University
• Collaborators: Istanbul University - Cerrahpasa
• Investigators: Principal Investigator: Melis USUL, RA., Istanbul Kent University

Study record dates

Study Major Dates

• Study Start (Actual): September 9, 2024
• Primary Completion (Actual): October 1, 2024
• Study Completion (Actual): November 15, 2024

Study Registration Dates

• First Submitted: July 7, 2024
• First Submitted That Met QC Criteria: July 16, 2024
• First Posted (Actual): July 18, 2024

Study Record Updates

• Last Update Posted (Estimated): December 2, 2024
• Last Update Submitted That Met QC Criteria: November 29, 2024
• Last Verified: November 1, 2024

More Information

Terms related to this study

• Keywords: Sleep Quality; body composition; Respiratory Function Tests
• Additional Relevant MeSH Terms: Body Weight
• Other Study ID Numbers: IstanbulKentU-FTR-MU-02

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No