Thenar Muscle Ultrasound in CTS Evaluation

Is Ultrasound Measurement of Thenar Muscle Cross-Sectional Area Useful in the Evaluation of Carpal Tunnel Syndrome?: A Controlled Study

This study will include 20 patients aged 18-75 years who have been diagnosed with carpal tunnel syndrome (CTS) based on electrophysiological examinations performed within the last three months, as well as 20 healthy volunteers without a CTS diagnosis. Sociodemographic data such as age, gender, height, weight, and BMI will be recorded. Pinch grip strength will be evaluated using a Jamar pinch meter, and hand grip strength will be assessed using a Jamar dynamometer. Ultrasound will be used to measure the cross-sectional area and thickness of the thenar muscles as well as the cross-sectional area of the median nerve. Additionally, previous electrophysiological examination results will be recorded for the CTS patients.

Study Overview

• Status: Not yet recruiting
• Conditions: Carpal Tunnel Syndrome
• Intervention / Treatment: Other: No intervention

• Study Type: Observational
• Enrollment (Estimated): 40

Contacts and Locations

• Study Contact: Name: Büşra Şirin Ahısha, MD; Phone Number: 02124443322; Email: bsrn080@gmail.com

Study Locations

• Turkey
  • Beylikdüzü
    • Istanbul, Beylikdüzü, Turkey, 34147
      • Beylikdüzü State Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: N/A

• Sampling Method: Probability Sample

Study Population

Carpal tunnel syndrome and healthy controls

Description

Inclusion Criteria:

• Patients aged 18-75 years.
• Diagnosed with carpal tunnel syndrome based on electrophysiological examination within the last 3 months.
• Healthy volunteers without a diagnosis of carpal tunnel syndrome.
• Volunteered to participate in the study.

Exclusion Criteria:

• Refusal to participate in the study.
• History of surgery due to carpal tunnel syndrome.
• Presence of neuromuscular diseases.
• Presence of advanced osteoarthritis.
• Presence of psychiatric disorders.
• Presence of cognitive impairments that may hinder study participation.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Carpal tunnel syndrome; Patients with carpal tunnel syndrome	Other: No intervention; No intervention
Control group; Healthy controls without carpal tunnel syndrome	Other: No intervention; No intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thenar Muscle Cross-Sectional Area (Ultrasound)	Measurement of the cross-sectional area of the thenar muscles using ultrasound to determine muscle atrophy or changes associated with carpal tunnel syndrome.	0 day

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thenar Muscle Thickness (Ultrasound)	Assessment of the thickness of the thenar muscles using ultrasound to evaluate structural changes in patients with CTS.	0 day
Median Nerve Cross-Sectional Area (Ultrasound)	Measurement of the median nerve's cross-sectional area using ultrasound, a parameter commonly associated with CTS diagnosis and severity.	0 day
Pinch Grip Strength	Evaluated using the Jamar pinch meter, this outcome measures the functional strength of the thumb and index finger, which may be impaired in CTS.	0 day
Hand Grip Strength	Assessed with a Jamar dynamometer, this outcome measures overall hand strength and provides insights into functional limitations caused by CTS.	0 day

Collaborators and Investigators

• Sponsor: Beylikduzu State Hospital
• Investigators: Principal Investigator: Büşra Şirin Ahısha, Beylikdüzü State Hospital

Study record dates

Study Major Dates

• Study Start (Estimated): December 10, 2024
• Primary Completion (Estimated): January 10, 2025
• Study Completion (Estimated): January 10, 2025

Study Registration Dates

• First Submitted: December 9, 2024
• First Submitted That Met QC Criteria: December 9, 2024
• First Posted (Estimated): December 12, 2024

Study Record Updates

• Last Update Posted (Estimated): December 12, 2024
• Last Update Submitted That Met QC Criteria: December 9, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Wounds and Injuries; Pathologic Processes; Neuromuscular Diseases; Peripheral Nervous System Diseases; Disease; Median Neuropathy; Mononeuropathies; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Syndrome; Carpal Tunnel Syndrome
• Other Study ID Numbers: BeylikduzuStateH12

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No