AI in Hypertension Treatment Education: Comparing GPT and Traditional Methods (AIHT-EDU)

Application of Artificial Intelligence in Hypertension Pharmacotherapy Education: A Comparative Study of the GPT System and Traditional Teaching Methods

Educational Trial: GPT-Based Training vs. Traditional Teaching for Hypertension Management

The goal of this educational trial is to determine whether a Generative Pre-trained Transformer (GPT)-based training system is more effective than traditional teaching methods in helping medical students master hypertension management plans. It will also evaluate the educational effectiveness and engagement of the GPT-based system. The main questions it aims to answer are:

Does the GPT-based training improve the ability of students to develop effective hypertension management plans compared to traditional methods? How do students perceive the use of the GPT system in their learning process? Researchers will compare the GPT-based training system to traditional teaching methods to see if the innovative AI approach enhances learning outcomes in medical education.

Participants will:

Engage with either the GPT-based system or traditional teaching materials. Visit the educational facility periodically for assessments and feedback sessions.

Keep a diary of their learning experiences, noting any difficulties or advantages they observe in the training method they are assigned.

Study Overview

• Status: Completed
• Conditions: Hypertension; Medical Education; GPT
• Intervention / Treatment: Behavioral: GPT-based training; Behavioral: traditional training

• Study Type: Interventional
• Enrollment (Actual): 52
• Phase: Not Applicable

Contacts and Locations

Study Locations

• China
  • Anhui
    • Hefei, Anhui, China, 230601
      • 678 Furong Road, Economic Development Zone, Hefei City, Anhui Province, China

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Graduate or regulatory trainee, currently rotating in cardiology and willing to participate in research.
• Age between 18-30 years old, gender not limited.
• No specialized training experience in hypertension diagnosis and treatment, only possessing basic medical theoretical knowledge.
• Able to accept a 4-week teaching intervention (2 hours of study per week).
• Sign the informed consent form and be aware of the research purpose and process.

Exclusion Criteria:

• Graduate students or trained interns who have received specialized training in hypertension medication treatment.
• Students unable to complete the full course of study (e.g., rotations shorter than four weeks or potential mid-course withdrawal).
• Unable to consistently participate in educational interventions (e.g., conflicts with study schedule).
• Have severe physical or mental health issues that may affect the learning process.
• Have language comprehension barriers or cognitive impairments, making it difficult to complete learning tasks.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: GPT-based training; Generative Pre-trained Transformer (GPT)-based training system	Behavioral: GPT-based training; GPT-based training whether could improve the ability of students to develop effective hypertension management plans
Active Comparator: traditional training; traditional training method	Behavioral: traditional training; traditional teaching methods

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
structured theoretical exam scores	Structured Theoretical Exam Scores - Immediate and One-Month Follow-Up: This outcome measures the effectiveness of teaching hypertension management. Students take a structured theoretical exam immediately after the training and again one month later to assess knowledge retention. The exam covers hypertension pathophysiology, risk factors, diagnostics, and treatments. Scores range from 0 to 100, with higher scores indicating better knowledge acquisition and retention.	From enrollment to the end of treatment at 4 weeks
Clinical Case Test Scores on Hypertension	Clinical Case Test Scores on Hypertension - Immediate and One-Month Follow-Up:This outcome measures how well students apply theoretical knowledge to practical clinical scenarios. Tests are administered immediately after training and one month later, involving clinical simulations where students diagnose hypertension and develop treatment plans. Scores range from 0 to 100, with higher scores indicating better clinical reasoning and application of knowledge.	From enrollment to the end of treatment at 4 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mood Elevation Scale	This outcome measures the intensity of emotions felt by students during learning. Participants rate statements on a Likert scale from 1 to 5, where 1 represents "not felt at all" and 5 represents "felt very intensely". Higher scores indicate a stronger emotional response to the learning experience.	From enrollment to the end of treatment at 4 weeks
Cognitive Load Index (CLI)	This outcome assesses the cognitive load experienced by students during learning. Participants rate statements on a Likert scale from 1 to 5, where 1 represents "strongly disagree" and 5 represents "strongly agree". Higher scores indicate a higher perceived cognitive load during learning.	From enrollment to the end of treatment at 4 weeks
Teaching Satisfaction Assessment	This outcome evaluates student satisfaction with the teaching methods. Participants rate their experience on a Likert scale from 1 to 5, where 1 represents "strongly disagree" and 5 represents "strongly agree". Higher scores indicate greater satisfaction with the teaching method.	From enrollment to the end of treatment at 4 weeks
Technology Acceptance Model	This outcome assesses students' acceptance of the GPT system. The questionnaire uses a Likert scale from 1 to 5, where 1 represents "strongly disagree" and 5 represents "strongly agree". Higher scores indicate greater acceptance, usability, and satisfaction with the GPT system.	From enrollment to the end of treatment at 4 weeks

Collaborators and Investigators

• Sponsor: zhen wang
• Investigators: Study Chair: xianrui luo, The Second Hospital of Anhui Medical University

Study record dates

Study Major Dates

• Study Start (Actual): October 20, 2024
• Primary Completion (Actual): July 12, 2025
• Study Completion (Actual): July 30, 2025

Study Registration Dates

• First Submitted: December 27, 2024
• First Submitted That Met QC Criteria: January 9, 2025
• First Posted (Actual): January 15, 2025

Study Record Updates

• Last Update Posted (Estimated): December 9, 2025
• Last Update Submitted That Met QC Criteria: December 8, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Vascular Diseases; Cardiovascular Diseases; Hypertension
• Other Study ID Numbers: 2023jyxm1150 (Other Grant/Funding Number: 2023 Anhui Province Quality Engineering Project)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No