Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls

April 30, 2026 updated by: Washington University School of Medicine
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences. We will explore how pubertal development and experiences of rejection influence these relationships.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

250

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • United States
    • Missouri
      • St Louis, Missouri, United States, 63110
        • Recruiting
        • Washington University School of Medicine
        • Contact:
          • Hailey

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • female aged 10-11 years
  • engagement in social media use
  • proficient in the English language
  • family/personal device that can complete daily diaries

Exclusion Criteria:

  • previously diagnosed chronic medical illness
  • autism spectrum disorder
  • significant developmental or speech delay
  • endocrine disorder
  • not assigned female at birth (AFAB)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: All participants
All participants complete the study intervention
Behavioral: Social Rejection Task
All participants will receive this

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Psychopathology symptoms parent report
Time Frame: "Through study completion, an average of two years"
Measured via the KSADS interview
"Through study completion, an average of two years"
Psychopathology symptoms child report
Time Frame: "Through study completion, an average of two years"
Measured via the KSADS interview
"Through study completion, an average of two years"
Daily Diary Social Media experiences
Time Frame: Through study completion, an average of two years
Assessed through daily diary reports (e.g., 'Did you use social media today?")
Through study completion, an average of two years
MicroEMA Social Media experiences
Time Frame: Through study completion, an average of two years
Assessed through microEMA prompt (e.g., 'using Social Media?")
Through study completion, an average of two years
Social Media experiences child report
Time Frame: Through study completion, an average of two years
Assessed through a screen time questionnaire
Through study completion, an average of two years
Social Media experiences parent report
Time Frame: Through study completion, an average of two years
Assessed through a screen time questionnaire
Through study completion, an average of two years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Washington University School of Medicine

Collaborators

St. Louis University
Northeastern University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 5, 2025

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 30, 2029

Study Registration Dates

First Submitted

December 30, 2024

First Submitted That Met QC Criteria

January 10, 2025

First Posted (Actual)

January 16, 2025

Study Record Updates

Last Update Posted (Actual)

May 6, 2026

Last Update Submitted That Met QC Criteria

April 30, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1R01MH135480-01A1-202407113
  • 1R01MH135480-01A1 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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