Effects of Resistance Exercise Compared to Whole-body Electromyostimulation in Young Female Dentists. (FeDeBoMa)

January 29, 2026 updated by: University of Erlangen-Nürnberg Medical School

Effects of a Single Bout of High Intensity, High Velocity Resistance Exercise Compared to Whole-body Electromyostimulation on Cardiometabolic Risk Factors and Markers of Bone Formation and -Resorption in Young Female Dentists.

Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnitude and velocity are commonly considered to be a feasible option to prevent bone loss in the early years of young adulthood. In parallel, whole-body electromyostimulation (WB-EMS) a trainings technology able address all main muscle groups simultaneously, however with dedicated exercise intensity might be a time-effective, joint friendly and safe option to maintain BMD in people unable or unmotivated to exercise conventionally. In the present study, we aim to compare the effects of a single session of WB-EMS versus high intensity, high velocity resistance exercise on biomarkers of bone formation (Procollagen type 1 N propeptide, P1NP) and resorption (C-terminal telopeptide of type I collagen, CTX-I). We hypothesize that no clinically relevant different effects on P1NP and CTX-I were determined.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

16

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Erlangen, Germany, 91054
        • Institute of Radiology, University Hospital NErlangen
      • Erlangen, Germany, 91052
        • Institute of Radiology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • female dental students (>3rd semester) or licensed dentists
  • no competitive sports background for >2 years
  • normal body mass (BMI>18,5 and <25 kg/m2)

Exclusion Criteria:

  • more than one resistance exercise session per week (last 12 month)
  • whole-body electromyostimulation during the last 12 month
  • amenorrhea, oligomenorrhea

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Whole-Body Electromyostimulation
One single bout of whole-body electromyostimulation (20 min, bipolar, 85 Hz, 350 µs, rectangular, 6s of impulse, 4s of rest)
Other: Whole-Body Electromyostimulation
20 min of WB-EMS (bipolar, 85 Hz, 350 µs, 6s impulse - 4s impulse break)
Active Comparator: Resistance exercise
High intensity, high velocity resistance exercise (30 min, 5-6 exercises, 3 sets at 60-85% 1RM)
Other: Resistance exercise
High-intensity/high velocity multiple set resistance exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise
Time Frame: Immediately pre-exercise to 15 min post exercise of a single exercise session
Changes for C-terminal telopeptide of type I collagen (CTX-I) serum levels from pre- to 15 min post-exercise as determined by blood samples
Immediately pre-exercise to 15 min post exercise of a single exercise session

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Changes for Procollagen type 1 N propeptide from pre- to 15 min post-exercise
Time Frame: Immediately pre-exercise to 15 min post exercise of a single exercise session
Changes for Procollagen type 1 N propeptide (P1NP) serum levels from pre- to 15 min post-exercise as determined by blood samples
Immediately pre-exercise to 15 min post exercise of a single exercise session
Changes for resting glucose from pre- to 15 min post-exercise
Time Frame: Immediately pr to 15 min post-exercise of a single exercise session
Changes for resting glucose serum levels from pre- to 15 min post-exercise as determined by blood samples
Immediately pr to 15 min post-exercise of a single exercise session
Changes for hemoglobin A1c from pre- to 15 min post-exercise
Time Frame: Immediately pre- to 15 min post-exercise of a single exercise session
Changes for hemoglobin A1c (HBA1C) serum levels from pre- to 15 min post-exercise as determined by blood samples
Immediately pre- to 15 min post-exercise of a single exercise session

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Erlangen-Nürnberg Medical School

Investigators

  • Principal Investigator: Wolfgang Kemmler, PhD, University Hospital Erlangen, Germany

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 15, 2025

Primary Completion (Actual)

July 15, 2025

Study Completion (Actual)

August 30, 2025

Study Registration Dates

First Submitted

February 3, 2025

First Submitted That Met QC Criteria

February 3, 2025

First Posted (Actual)

February 6, 2025

Study Record Updates

Last Update Posted (Actual)

January 30, 2026

Last Update Submitted That Met QC Criteria

January 29, 2026

Last Verified

June 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FeDeBoMa02
  • UKER (Other Identifier: University Hospital Erlangen, Germany)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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