Cavitaion vs W-BEMS on Central Obesity (w-bems)

Cavitation Versus Whole-Body Electromyostimulation on Infilamatory Markers in Centeral Obesity

The purpose of this study is to compare the effects of ultrasound cavitation and whole-body electromyostimulation (WB-EMS) on inflammatory markers in individuals with central obesity.

Study Overview

• Status: Active, not recruiting
• Conditions: Central Obesity
• Intervention / Treatment: Device: cavitation, whole body electromyostimulation

Detailed Description

Sixty individuals with central obesity were recruited from private clinics. And underwent a screening process to determine their eligibility based on the inclusion and exclusion criteria. Eligible participants were informed about the study details, procedures, potential risks, and benefits before obtaining written informed consent

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Qalyubia Governorate
    • Cairo, Qalyubia Governorate, Egypt, 13611
      • Cairo University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Adults aged 18-50 years.
• Individuals diagnosed with central obesity, defined as a waist circumference greater than 102 cm in men and 88 cm in women.
• Participants with a stable body weight for at least three months prior to the study.
• No engagement in regular physical activity or weight loss programs in the past six months.
• Willingness to adhere to study protocols and attend all scheduled sessions.

Exclusion Criteria:

• Individuals with chronic diseases other than obesity-related conditions, such as cardiovascular disease, diabetes, or severe hypertension.

  • Pregnant or lactating women.
  • Individuals with implanted electronic devices (e.g., pacemakers).
  • Participants with dermatological conditions or skin infections in the treatment area.
  • Individuals undergoing medication that may affect fat metabolism or inflammatory markers.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: group A (Study group); Participants in this cohort were administered localized ultrasound cavitation treatments. Each session was approximately 30 minutes in duration, with treatments scheduled twice a week. In addition, participants received mediterranean diet	Device: cavitation, whole body electromyostimulation; The duration of the study was set for 12 weeks. Assessments were meticulously conducted at both the baseline and the conclusion of the study period to evaluate outcomes across the different groups.
Experimental: group B (Study group); : Participants assigned to this cohort underwent whole- body electromyostimulation (WB-EMS) therapy. These sessions were 20 minutes long, also occurring twice weekly. Participants also received mediterranean diet.	Device: cavitation, whole body electromyostimulation; The duration of the study was set for 12 weeks. Assessments were meticulously conducted at both the baseline and the conclusion of the study period to evaluate outcomes across the different groups.
Sham Comparator: Group C (Control Group); Participants in this control group receive mediterranean diet. Additionally, they participated in all assessment procedures, ensuring a comprehensive comparative analysis.	Device: cavitation, whole body electromyostimulation; The duration of the study was set for 12 weeks. Assessments were meticulously conducted at both the baseline and the conclusion of the study period to evaluate outcomes across the different groups.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Inflammatory Markers	Measurement of changes in levels of Tumor Necrosis Factor-alpha (TNF-alpha), and Interleukin-6 (IL-6) using ELISA (Enzyme-Linked Immunosorbent Assay) kits.	3 Monthes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Waist Circumference	Will be measured at the level of the iliac crest using a standard measuring tape to assess changes in central adiposity.	3 Monthes
Body Weight	Standard clinical scales to measure body weight at each visit to track changes over the study period.	3 Monthes
Body Mass Index (BMI)	Will be calculated using measured height and weight (kg/m²) to observe changes in overall body mass classification.	3 Monthes

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): September 5, 2024
• Primary Completion (Actual): November 5, 2024
• Study Completion (Estimated): January 4, 2026

Study Registration Dates

• First Submitted: August 26, 2025
• First Submitted That Met QC Criteria: December 19, 2025
• First Posted (Actual): December 29, 2025

Study Record Updates

• Last Update Posted (Actual): December 29, 2025
• Last Update Submitted That Met QC Criteria: December 19, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nutrition Disorders; Overnutrition; Body Weight; Overweight; Obesity; Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Signs and Symptoms; Obesity, Abdominal
• Other Study ID Numbers: 012/005581

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No