To Develop and Introduce Into Polyclinic Practice a Register of Patients with Experience of Myocardial Infarction and Acute Cerebrovascular Disease

This is a retrospective observational study using the methodology of creating medical registries. The expected number of patients included in the registry is about 2000 patients with myocardial infarction and/or ACVD of any duration and concomitant non-cardiac diseases of therapeutic profile in pilot healthcare organizations for any reason during 2019-2022 based on the source medical records data.

Study Overview

• Status: Active, not recruiting
• Conditions: Myocardial Infarction (MI); Acute Cardiovascular Disease

Detailed Description

The implementation of the task results will improve the efficiency of secondary and tertiary prevention of diseases of the circulatory system - pathology that makes the greatest contribution to the main medical-demographic and socio-economic losses of the state by determining the number of groups with the highest risk of death in outpatient and polyclinic institutions among patients after myocardial infarction, ACVD, living in the Republic of Belarus, to create programs of additional measures to reduce morbidity and mortality of the population based on a comparison of register data and official statistical forms, which will ultimately affect the reduction in the incidence of non-fatal recurrent cardiovascular events in individuals after AMI, ACVD and / or their combination of any duration in the range of 0.2-1% of the indicators determined during the study.

• Study Type: Observational
• Enrollment (Estimated): 2000

Contacts and Locations

Study Locations

• Belarus
  • Minsk, Belarus, 220036
    • Republican Scientific and Practical Center of Cardiology

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

All patients who applied to the pilot ambulatory health care organizations between 2019-2022 in order to identify and "look for" patients after acute cardiovascular event, but who were not monitored for that event for various reasons (statute of limitations, refusal, relocation, etc.); meeting the inclusion criteria and not meeting the exclusion criteria.

Description

Inclusion Criteria:

1. All patients who applied to the pilot ambulatory health care organizations between 2019-2022 in order to identify and "look for" patients after acute cardiovascular event, but who were not monitored for that event for various reasons (statute of limitations, refusal, relocation, etc.);
2. All patients discharged from hospitals with a final diagnosis of AMI/ACVD, assigned territorially to the pilot polyclinics in the period 2019-2022.
3. Presence of a history of AMI and/or ACVD;
4. Age 18 years and older.

Exclusion Criteria:

• No

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
myocardial infarction; Some patients with non-fatal myocardial infarction
acute cerebrovascular disease; Hospitalization due to cardiovascular diseases, some patients with hospitalization due to cardiovascular diseases

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mortality from other causes	number of deaths from other diseases	3 years

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to combined end point	non-fatal myocardial infarction or non-fatal cerebral stroke or coronary/carotid revascularization	3 years
Proportion of patients with non-fatal myocardial infarction	non-fatal myocardial infarction	3 years
Proportion of patients with non-fatal cerebral stroke	non-fatal cerebral stroke	3 years
Proportion of patients with COVID-19 cases during follow-up	COVID-19 cases during follow-up	3 years
Hospitalization due to cardiovascular diseases	Proportion of patients with hospitalization due to cardiovascular diseases	3 years
COVID-19-related hospitalization	Pproportion of patients with COVID-19-related hospitalization	3 years

Collaborators and Investigators

• Sponsor: State Institution "Republican Scientific and Practical Center" Cardiology, Belarus

Study record dates

Study Major Dates

• Study Start (Actual): March 1, 2024
• Primary Completion (Estimated): December 31, 2025
• Study Completion (Estimated): June 1, 2026

Study Registration Dates

• First Submitted: February 4, 2025
• First Submitted That Met QC Criteria: February 4, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: February 4, 2025
• Last Verified: February 1, 2025

More Information

Terms related to this study

• Keywords: myocardial infarction; cardiovascular diseases; multimorbidity; registry; chronic non-communicable diseases; acute cerebrovascular disease
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Pathologic Processes; Heart Diseases; Necrosis; Myocardial Ischemia; Ischemia; Cardiovascular Diseases; Cerebrovascular Disorders; Myocardial Infarction; Infarction
• Other Study ID Numbers: 2161/29590637

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: Protection of personal data

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No