- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06884566
Effect of Acute Supplementation (taurine) on Maximal Strength and Anaerobic Power
March 13, 2025 updated by: Kyriaki Antoniou, University of Central Lancashire Cyprus
This crossover-design study examines the acute effect of taurine on trained individuals aged 18-40 on strength and power outputs.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
The purpose of this study is to further investigate any potential ergogenic effects offered by taurine, under specific conditions, namely that of acute supplementation, as opposed to the chronic supplementation protocols of many popular ergogenic aids, such as creatine and beta alanine.
Exercise modes investigated include maximal isometric strength, maximal instantaneous power generation, and sustained maximal anaerobic power output, investigated via grip strength, vertical jump height, and the Wingate test, respectively.
Study Type
Interventional
Enrollment (Actual)
17
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Pyla
-
Larnaca, Pyla, Cyprus, 7080
- University of Central Lancashire Cyprus
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- participants 18 - 40 years of age
- physically active or recreationally active with consistent training more than 3 times per week for at least 6 months
- non-smokers
Exclusion Criteria:
- cardiovascular, respiratory or metabolic diseases
- any musculoskeletal injury in the last six months
- taking taurine and/or creatine supplementation in the past three months
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Taurine supplementation
Participants consumed 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink.
|
For the intervention trials participants consumed the following in randomized order: 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink or placebo which was a sugar-free lemonade drink with nothing added, 60 minutes before the exercise protocols.
Participants wore a nose plug during consumption to confirm that no taste differences were discernible between trials.
|
|
Placebo Comparator: Placebo
Placebo was a 500ml sugar-free lemonade drink with nothing added
|
For the intervention trials participants consumed the following in randomized order: 50mg·kg -1 of taurine diluted in 500ml of a sugar-free lemonade drink or placebo which was a sugar-free lemonade drink with nothing added, 60 minutes before the exercise protocols.
Participants wore a nose plug during consumption to confirm that no taste differences were discernible between trials.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Maximal Isometric strength in kilograms assessed via handgrip test
Time Frame: Day 1
|
Day 1
|
|
Relative Isometric strength in kilograms assessed via handgrip test
Time Frame: Day 1
|
Day 1
|
|
Maximal Instantaneous power generation in W/kg assessed via vertical jump height test.
Time Frame: Day 1
|
Day 1
|
|
Average Instantaneous power generation in W/kg assessed via vertical jump height test.
Time Frame: Day 1
|
Day 1
|
|
Peak power in Watts assessed via the Wingate Anaerobic test
Time Frame: Day 1
|
Day 1
|
|
Maximal Isometric strength in kilograms assessed via handgrip test
Time Frame: After 48 hours
|
After 48 hours
|
|
Relative Isometric strength in kilograms assessed via handgrip test
Time Frame: After 48 hours
|
After 48 hours
|
|
Maximal Instantaneous power generation in W/kg assessed via vertical jump height test.
Time Frame: After 48 hours
|
After 48 hours
|
|
Average Instantaneous power generation in W/kg assessed via vertical jump height test.
Time Frame: After 48 hours
|
After 48 hours
|
|
Peak power in Watts assessed via the Wingate Anaerobic test
Time Frame: After 48 hours
|
After 48 hours
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Efstathios Christodoulides, PhD, https://www.uclancyprus.ac.cy/
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 7, 2025
Primary Completion (Actual)
January 21, 2025
Study Completion (Actual)
January 21, 2025
Study Registration Dates
First Submitted
January 23, 2025
First Submitted That Met QC Criteria
March 13, 2025
First Posted (Actual)
March 25, 2025
Study Record Updates
Last Update Posted (Actual)
March 25, 2025
Last Update Submitted That Met QC Criteria
March 13, 2025
Last Verified
January 1, 2025
More Information
Terms related to this study
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.