COMPARISON OF EFFECTS OF GABAPENTIN AND CLONIDINE ON POST-OPERATIVE PAIN AND ANXIETY IN LUMBAR SPINAL SURGERY.

January 8, 2026 updated by: ADABALA VIJAY BABU, Shri Guru Ram Rai Institute of Medical and Health Sciences

Gabpentin vs Clonidine for Post Operative Pain

the investigators have tested whether gabapentin is superior to clonidine top decrease the post operative pain during spinal surgeries as a part of their thesis study. the investigators are registering this study post date as the student forgot by mistake to do so.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

90

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • India
    • Uttarakhand
      • Dehradun, Uttarakhand, India, 246001
        • Adabala Vijay Babu

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

- Eligible participants were aged 18-60 years, classified as ASA physical status I or II, and scheduled for one or two-level lumbar laminectomy.

Exclusion Criteria:

  • Patients with psychiatric disorders, autoimmune diseases, local infection, BMI >35, emergency procedures, tumour surgeries and the patients requiring the postoperative ventilation were excluded

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: clonide
In this group the investigators have given clonidine to the participants
Drug: Gabapentin
comparison of both these drugs to decrease pain
Other Names:
  • clonidine
Placebo Comparator: placebo
in this group no active drug was given to the participants
Drug: Gabapentin
comparison of both these drugs to decrease pain
Other Names:
  • clonidine
Active Comparator: gabapentin
In this group the investigators have given gabapentin to the participants
Drug: Gabapentin
comparison of both these drugs to decrease pain
Other Names:
  • clonidine

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
post operative pain
Time Frame: 1, 2, 4, 6, 8, 12, and 24 hours postoperatively.
Pain was assessed using the Visual Analog Scale (VAS) score ranging from 0 to 10. 10 being the worst pain and 0 being No pain
1, 2, 4, 6, 8, 12, and 24 hours postoperatively.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
anxiety
Time Frame: 1, 2, 4, 6, 8, 12, and 24 hours postoperatively.
anxiety was evaluated using Hamilton Anxiety Rating Scale (HAM-A). Each item is scored on a scale of 0 (not present) to 4 (severe), with a total score range of 0-56, where <17 indicates mild severity, 18-24 mild to moderate severity and 25-30 moderate to severe.
1, 2, 4, 6, 8, 12, and 24 hours postoperatively.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Shri Guru Ram Rai Institute of Medical and Health Sciences

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 20, 2022

Primary Completion (Actual)

January 20, 2024

Study Completion (Actual)

March 20, 2024

Study Registration Dates

First Submitted

November 19, 2025

First Submitted That Met QC Criteria

December 17, 2025

First Posted (Estimated)

December 22, 2025

Study Record Updates

Last Update Posted (Estimated)

January 12, 2026

Last Update Submitted That Met QC Criteria

January 8, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 14

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

we can share our research question and methodology whenever it is necessary

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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