Attitudes and Perceptions of Corresponding Authors From Top International Medical Journals Regarding the Use of Artificial Intelligence in the Scientific Process (AISurvey6 A+)

"Artificial intelligence (AI), including large language models and conversational tools, is increasingly being used in medical research. These tools may assist researchers at different stages of the scientific process, such as generating research ideas, reviewing the literature, analyzing data, writing manuscripts, and preparing articles for publication. While interest in AI is growing rapidly, there is still limited information on how these tools are actually perceived and used by leading medical researchers. This study aims to better understand the attitudes, perceptions, and self-reported uses of artificial intelligence among corresponding authors who have published in six major international medical journals. These authors play a key role in shaping scientific standards and editorial practices, and their views are essential to understanding how AI may influence the future of medical research. Participants are invited to complete an anonymous online questionnaire that asks about their familiarity with AI tools, how and when they use or plan to use them in the research process, the potential benefits they perceive, and the concerns or limitations they identify. The survey also explores participants' expectations regarding transparency, ethical guidance, and journal policies related to the use of artificial intelligence in scientific work.The study is observational and does not involve any medical intervention or collection of personal or health-related data. Participation is voluntary, and responses are fully anonymous.

Study Overview

• Status: Enrolling by invitation
• Conditions: Artificial Intelligence; Surveys and Questionnaires; Biomedical Research; Scientific Publishing
• Intervention / Treatment: Other: observational survey

• Study Type: Observational
• Enrollment (Estimated): 500

Contacts and Locations

Study Locations

• France
  • Alpes Maritimes
    • Nice, Alpes Maritimes, France, 06000
      • CHU de Nice

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

The study population consists of corresponding authors who have published scientific articles in leading international medical journals. Participants are identified through publicly available publication data from six major journals (The New England Journal of Medicine, The Lancet, JAMA, Nature, Science, and The BMJ) and are invited to participate via professional email addresses. The population includes adult researchers from diverse biomedical and medical disciplines, with no geographic restriction.

Description

Inclusion Criteria:

• Participants without any disease, condition, or related symptoms are permitted to participate. This study is a non-clinical, observational survey focusing on attitudes and practices related to artificial intelligence in scientific research, not on health conditions.

Exclusion Criteria:

• Authors who are not corresponding authors.
• Students, residents, interns, or trainees without corresponding author status.
• Individuals not involved in biomedical or medical research activities.
• Individuals who decline to participate or do not complete the online questionnaire.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Authors Survey Group; This label identifies the single cohort of participants, consisting of corresponding authors invited to complete the anonymous online survey. No comparison or control groups are included.	Other: observational survey; This is an observational, non-interventional study based on an anonymous online questionnaire. No intervention is administered to participants.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Self-reported attitudes regarding the use of artificial intelligence in the scientific research process	Participants report their attitudes and perceptions regarding the use of artificial intelligence in the scientific research process through multiple-choice and Likert-scale items. Responses are analyzed descriptively; higher scores indicate more favorable attitudes toward the use of artificial intelligence.	At the inclusion
Perceptions regarding the use of artificial intelligence in the scientific research process	Participants report their attitudes and perceptions regarding the use of artificial intelligence in the scientific research process through multiple-choice and Likert-scale items. Responses are analyzed descriptively; higher scores indicate more favorable attitudes toward the use of artificial intelligence.	At the inclusion

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Self-reported patterns of use, regarding artificial intelligence tools in scientific research and publishing	Anonymous online questionnaire developed for this study Responses are collected using multiple-choice questions and Likert-scale items. Higher scores reflect greater reported use of artificial intelligence and more positive evaluations of its benefits, while higher concern scores reflect greater perceived risks or limitations	At the inclusion
Perceived benefits regarding artificial intelligence tools in scientific research and publishing	Anonymous online questionnaire developed for this study Responses are collected using multiple-choice questions and Likert-scale items. Higher scores reflect greater reported use of artificial intelligence and more positive evaluations of its benefits, while higher concern scores reflect greater perceived risks or limitations	At the inclusion
Risk regarding artificial intelligence tools in scientific research and publishing	Anonymous online questionnaire developed for this study Responses are collected using multiple-choice questions and Likert-scale items. Higher scores reflect greater reported use of artificial intelligence and more positive evaluations of its benefits, while higher concern scores reflect greater perceived risks or limitations	At the inclusion
Expectations regarding artificial intelligence tools in scientific research and publishing	Anonymous online questionnaire developed for this study Responses are collected using multiple-choice questions and Likert-scale items. Higher scores reflect greater reported use of artificial intelligence and more positive evaluations of its benefits, while higher concern scores reflect greater perceived risks or limitations	At the inclusion

Collaborators and Investigators

• Sponsor: Centre Hospitalier Universitaire de Nice

Study record dates

Study Major Dates

• Study Start (Actual): December 10, 2025
• Primary Completion (Estimated): March 10, 2026
• Study Completion (Estimated): June 30, 2026

Study Registration Dates

• First Submitted: December 24, 2025
• First Submitted That Met QC Criteria: December 24, 2025
• First Posted (Actual): January 8, 2026

Study Record Updates

• Last Update Posted (Actual): January 8, 2026
• Last Update Submitted That Met QC Criteria: December 24, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: 25Chirplast02

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No