Chewing Under Dual-Tasking in MS

January 16, 2026 updated by: Seda Nur Kemer, Ondokuz Mayıs University

The Effect of Different Dual-Task Conditions on Chewing Function in Individuals With Multiple Sclerosis

This study aims to investigate the effects of visual, auditory, and motor dual-task conditions on chewing performance in individuals with multiple sclerosis, compared with healthy controls.

Study Overview

Status

Not yet recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

48

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

The study population consisted of individuals with multiple sclerosis and age-matched healthy controls.

Description

Inclusion Criteria:

  • Individuals aged between 18 and 65 years
  • Mini-Mental State Examination (MMSE) score of 24 or higher
  • Right-hand dominance

Exclusion Criteria:

  • Presence of visual and/or hearing impairment
  • Presence of difficulties in solid food intake and/or complaints related to mastication
  • Presence of neurological, psychological, cognitive, and/or chronic conditions that may affect mastication or chewing function
  • History of interventions affecting oral structure (e.g., oral/maxillofacial surgery or radiotherapy) within the last month
  • Known allergy to the food used in the test

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Healthy Control
Multiple Sclerosis

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Test of Masticating and Swallowing Solids
Time Frame: Baseline (single-task and dual-task conditions assessed on the same day)
Test of Masticating and Swallowing Solids (TOMASS) is a standardized clinical assessment used to evaluate solid bolus mastication and swallowing performance.
Baseline (single-task and dual-task conditions assessed on the same day)
Mini-Mental State Examination (MMSE)
Time Frame: Baseline
The MMSE is a brief, widely used screening tool for assessing global cognitive function.
Baseline
Go/No-Go Test
Time Frame: Baseline (single-task and dual-task conditions assessed on the same day)
The Go/No-Go Test is a neuropsychological assessment used to evaluate response inhibition and sustained attention.
Baseline (single-task and dual-task conditions assessed on the same day)
Auditory Reaction Time Test
Time Frame: Baseline (single-task and dual-task conditions assessed on the same day)
The Auditory Reaction Time Test is used to assess auditory attention and the speed of motor response to auditory stimuli.
Baseline (single-task and dual-task conditions assessed on the same day)
Tap Tool
Time Frame: Baseline (single-task and dual-task conditions assessed on the same day)
The Tap Tool is a neuropsychological and motor performance assessment used to evaluate psychomotor speed and fine motor control.
Baseline (single-task and dual-task conditions assessed on the same day)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ondokuz Mayıs University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

January 26, 2026

Primary Completion (Estimated)

February 15, 2026

Study Completion (Estimated)

March 1, 2026

Study Registration Dates

First Submitted

January 9, 2026

First Submitted That Met QC Criteria

January 16, 2026

First Posted (Actual)

January 26, 2026

Study Record Updates

Last Update Posted (Actual)

January 26, 2026

Last Update Submitted That Met QC Criteria

January 16, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1919B012411772

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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