Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification

April 7, 2026 updated by: Ziad Mohamed Abdelaal Sayed, Assiut University
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study population will consist of adult patients aged 40 years and older diagnosed with cataract and scheduled for phacoemulsification surgery at Assiut University Hospital.

Description

Inclusion Criteria:

  • Age equals to or above 40 years old
  • cataract patient
  • suitable for phacoemulsification
  • clear corneal media

Exclusion Criteria:

  • previous corneal surgery
  • advanced glaucoma
  • corneal pathology (keratoconus, scarring)
  • retinal disease affecting vision
  • irregular astigmatism
  • contact lens use within the last 2 weeks

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
dry eye disease
dry eye disease patients who are not optimized before phacoemulsification
non dry eye disease
non dry eye disease patients before phacoemulsification
Procedure: dry eye disease optimization
dry eye disease management prior to obtaining intraocular lens power calculation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Compare mean absolute error (MAE) between patients with and without DED
Time Frame: 2 yeras
2 yeras
Compare mean absolute error (MAE) between patients with and without DED
Time Frame: 2 years
2 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 30, 2026

Primary Completion (Estimated)

April 30, 2028

Study Completion (Estimated)

April 30, 2029

Study Registration Dates

First Submitted

April 7, 2026

First Submitted That Met QC Criteria

April 7, 2026

First Posted (Actual)

April 13, 2026

Study Record Updates

Last Update Posted (Actual)

April 13, 2026

Last Update Submitted That Met QC Criteria

April 7, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • DED IOL power calculation

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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