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Shield Post-godkendelsesprotokol (SOLAR)

11. november 2026 opdateret af: Guardant Health, Inc.

The Shield post-approval study (PAS) is a prospective, longitudinal study supplemented with Real World Evidence (RWE) to evaluate the longitudinal performance of Shield in an average risk population at a second round of testing for individuals between the ages of 45 and 81 at average risk of CRC using colonoscopy as the reference method.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Colorectal cancer (CRC) is the fourth most diagnosed cancer and second leading cause of cancer-related death in the US, with an estimated 53,010 deaths attributable to CRC in 2024. The risk of CRC increases with age, with the majority of cases and deaths occurring in individuals aged 65 years or older. While the incidence of CRC in Americans 65 years of age or older has decreased over the last decade, the incidence of CRC in younger Americans aged 55 years or younger has been increasing since the mid-1990s. CRC disproportionately affects minority populations, with American Indian/Alaska Native and Black/African American populations having the highest incidence and mortality rates1; this is further exacerbated by systemic barriers to current CRC screening options.

CRC primarily arises from a precursor lesion, the adenomatous polyp (i.e., adenoma), that grows from the epithelial cells of the colorectal mucosa. Adenomas that grow larger than 10 mm or have elements indicating a risk of malignant transformation (e.g., high-grade dysplasia or villous features) are defined as advanced adenomas (AAs). The vast number of adenomas, even those with features classifying them as AAs, do not progress into a colorectal malignancy. Colonoscopy cannot always distinguish adenomas or advanced adenomas from other polyp histology; thus, polypectomy is routinely performed for lesions identified on endoscopy. The transition rate from adenoma onset to CRC development is estimated to be 12.5 to 25 years. This slow transition from adenoma onset to CRC onset allows for multiple CRC screening opportunities over a lifetime, providing the ability to intervene along the disease development course and the potential to detect and remove adenomas, prevent colorectal cancer, and reduce CRC incidence and subsequently, disease mortality.

Once CRC has developed, tumor staging is consistent with other solid tumors and defined based on how far the cancer has spread within the body. In Stage 0 (carcinoma in situ), the cancer cells are only in the colorectal mucosa. In Stage I, the cancer has spread to the muscular layer of the colorectum but not to nearby tissue or lymph nodes. In Stage II, the cancer has grown through the wall of the colorectum and potentially to nearby tissues but has not spread to nearby lymph nodes. In Stage III, the cancer has spread to nearby lymph nodes but not to distant parts of the body. In Stage IV, the cancer has spread to one or more distant parts of the body. The estimated time frame from CRC onset to a symptomatic diagnosis of CRC is estimated to be 4-5 years, in the absence of early detection through asymptomatic cancer screening. Tumor size and location can influence the rate of transition through the stages of CRC. The 5-year survival rate for localized disease (Stage I-II) is 91%, and is 72% for regional disease (Stage III), while the 5-year survival for metastatic disease (Stage IV) is only 14%. These statistics highlight the ability to reduce CRC-related mortality by detection of early-stage (Stage I-III) disease where therapeutic intervention has the potential to result in a cure.

Undersøgelsestype

Observationel

Tilmelding (Anslået)

3375

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Studiesteder

  • Forenede Stater
    • Arizona
      • Chandler, Arizona, Forenede Stater, 85224
        • Rekruttering
        • Southeast Valley Gastroenterology Consultants
        • Kontakt:
        • Ledende efterforsker:
          • Charles Schron
      • Gilbert, Arizona, Forenede Stater, 85297
        • Rekruttering
        • Southeast Valley Gastroenterology Consultants
        • Kontakt:
        • Ledende efterforsker:
          • Charles Schron
    • California
      • Anaheim, California, Forenede Stater, 92805
        • Rekruttering
        • Elite Primary Physicians, Inc.
        • Kontakt:
        • Ledende efterforsker:
          • Ishminder Singh, MD
      • Canoga Park, California, Forenede Stater, 91304
        • Rekruttering
        • Alliance Research Institute, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Cameron Sikavi
      • Garden Grove, California, Forenede Stater, 92840
        • Trukket tilbage
        • Paragon Rx Clinical, Inc.
      • Granada Hills, California, Forenede Stater, 91344
        • Rekruttering
        • Amicis Research Center
        • Kontakt:
        • Ledende efterforsker:
          • Pascal Dabel
      • Monterey Park, California, Forenede Stater, 91754
        • Rekruttering
        • Ace Research Institute
        • Kontakt:
        • Ledende efterforsker:
          • Yu-Hsiang Sam Lee, MD
      • Palm Springs, California, Forenede Stater, 92262
        • Rekruttering
        • Desert Oasis Healthcare Medical Group
        • Ledende efterforsker:
          • Michael F Jardula
        • Kontakt:
      • Sherman Oaks, California, Forenede Stater, 91403
        • Rekruttering
        • Amicis Research Center
        • Kontakt:
        • Ledende efterforsker:
          • Ali Sheybani, MD
      • Tarzana, California, Forenede Stater, 91356
        • Rekruttering
        • BioPartners, Inc
        • Kontakt:
          • Mila Gor
          • Telefonnummer: 818-712-9355
        • Ledende efterforsker:
          • Arkady Stern, MD
      • Valencia, California, Forenede Stater, 91355
        • Rekruttering
        • Amicis Research Center
        • Kontakt:
        • Ledende efterforsker:
          • Dennis Lewis, MD
      • Winnetka, California, Forenede Stater, 91306
        • Rekruttering
        • Coral Clinics
        • Kontakt:
        • Ledende efterforsker:
          • Amin Khorsandi, MD
      • Woodland Hills, California, Forenede Stater, 91367
        • Rekruttering
        • BioPartners, Inc
        • Ledende efterforsker:
          • Arkady Stern, MD
        • Kontakt:
    • Connecticut
      • Branford, Connecticut, Forenede Stater, 06405
        • Rekruttering
        • Digestive Disease Associates
        • Kontakt:
        • Ledende efterforsker:
          • Daniel Zanchetti
        • Kontakt:
        • Ledende efterforsker:
          • Daniel Zanchetti, MD
    • Florida
      • Boca Raton, Florida, Forenede Stater, 33486
        • Rekruttering
        • Gastroenterology Consultants of Boca Raton, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Todd Eisner
      • Delray Beach, Florida, Forenede Stater, 33484
        • Rekruttering
        • Manuel Espinel MD PA
        • Kontakt:
        • Ledende efterforsker:
          • Manuel Espinel, MD
      • Doral, Florida, Forenede Stater, 33172
        • Rekruttering
        • Innova Pharma Research, LLC
        • Ledende efterforsker:
          • Giralt Yanez, MD
        • Kontakt:
      • Miami, Florida, Forenede Stater, 33134
        • Rekruttering
        • Research Associates of South Florida, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Christian Andrade, MD
      • Miami, Florida, Forenede Stater, 33134
        • Rekruttering
        • Marisela Gonzalez, MD
        • Kontakt:
        • Ledende efterforsker:
          • Marisela Gonzalez, MD
      • Miami, Florida, Forenede Stater, 33166
        • Rekruttering
        • Florida South Research Phase I-IV, Inc.
        • Kontakt:
        • Ledende efterforsker:
          • Eduardo Viera, MD
      • North Miami, Florida, Forenede Stater, 33181
        • Rekruttering
        • Physicians Group of South Florida
        • Kontakt:
        • Ledende efterforsker:
          • Daniel Wolfson
      • Tamarac, Florida, Forenede Stater, 33321
        • Rekruttering
        • Infinity Life Research Group, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Lazaro Diaz, MD
      • Tampa, Florida, Forenede Stater, 33607
        • Rekruttering
        • NMC Research
        • Kontakt:
        • Ledende efterforsker:
          • Osvanny Nodal, MD
      • Tampa, Florida, Forenede Stater, 33634
        • Rekruttering
        • Top Research of West Florida, LLC
        • Ledende efterforsker:
          • Jorge Castillo Molina, MD
        • Kontakt:
    • Georgia
      • Conyers, Georgia, Forenede Stater, 30094
        • Rekruttering
        • Keith Family Medicine
        • Kontakt:
        • Ledende efterforsker:
          • Nabil Keith, MD
      • Dawsonville, Georgia, Forenede Stater, 30534
        • Rekruttering
        • Keith Family Medicine
        • Ledende efterforsker:
          • Nabil Keith, MD
        • Kontakt:
      • Fayetteville, Georgia, Forenede Stater, 30214
        • Rekruttering
        • Primeway Clinical Research Group
        • Kontakt:
        • Ledende efterforsker:
          • Charlita Worthy, MD
      • Snellville, Georgia, Forenede Stater, 30078
        • Rekruttering
        • CLINsearch at Renew Health Clinical Research
        • Kontakt:
        • Ledende efterforsker:
          • Ayyaz Qureshi, MD
    • Illinois
      • Bourbonnais, Illinois, Forenede Stater, 60914
        • Rekruttering
        • Digestive Disease Consultants
        • Ledende efterforsker:
          • Ashish Shah, MD
        • Kontakt:
        • Kontakt:
        • Ledende efterforsker:
          • Ashish Shah
      • Champaign, Illinois, Forenede Stater, 61822
      • Champaign, Illinois, Forenede Stater, 61822
        • Aktiv, ikke rekrutterende
        • Christie Clinic
      • Chicago, Illinois, Forenede Stater, 60631
        • Rekruttering
        • GI Solutions of Illinois
        • Ledende efterforsker:
          • Charles Berkelhammer, MD
        • Kontakt:
        • Ledende efterforsker:
          • Charles Berkelhammer
        • Kontakt:
      • Downers Grove, Illinois, Forenede Stater, 60515
        • Rekruttering
        • Digestive Health Services
        • Ledende efterforsker:
          • Charles Berkelhammer, MD
        • Kontakt:
        • Ledende efterforsker:
          • Charles Berkelhammer
        • Kontakt:
      • Lake Barrington, Illinois, Forenede Stater, 60010
        • Rekruttering
        • Gastroenterology and Internal Medicine Specialists (GAIMS)
        • Kontakt:
        • Kontakt:
        • Ledende efterforsker:
          • Nicole Gentile
        • Ledende efterforsker:
          • Nicole Gentile, MD
      • Libertyville, Illinois, Forenede Stater, 60048
        • Rekruttering
        • Northshore Center for Gastroenterology (NCG)
        • Kontakt:
        • Ledende efterforsker:
          • Nicole Gentile, MD
      • Oak Lawn, Illinois, Forenede Stater, 60453
        • Rekruttering
        • Southwest Gastroenterology (SWG)
        • Ledende efterforsker:
          • Charles Berkelhammer, MD
        • Kontakt:
        • Ledende efterforsker:
          • Charles Berkelhammer
        • Kontakt:
    • Indiana
      • Munster, Indiana, Forenede Stater, 46321
        • Rekruttering
        • Center for Digestive Health
        • Kontakt:
        • Ledende efterforsker:
          • Navin Kumar, MD
    • Kansas
      • Hutchinson, Kansas, Forenede Stater, 67502
        • Aktiv, ikke rekrutterende
        • Hutchinson Clinic
    • Louisiana
      • Covington, Louisiana, Forenede Stater, 70433
        • Rekruttering
        • Northlake Gastroenterology Associates
        • Kontakt:
        • Ledende efterforsker:
          • Gregory Mula
      • Hammond, Louisiana, Forenede Stater, 70403
        • Rekruttering
        • Northlake Gastroenterology Associates
        • Kontakt:
        • Ledende efterforsker:
          • Gregory Mula
    • Maryland
      • Olney, Maryland, Forenede Stater, 20832
        • Rekruttering
        • Olney Medical Group
        • Kontakt:
        • Ledende efterforsker:
          • Gaurang Thaker, MD
    • Michigan
      • Bloomfield Township, Michigan, Forenede Stater, 48302
        • Rekruttering
        • Embassy Research Network
        • Kontakt:
        • Ledende efterforsker:
          • Priyesh Patel, MD
      • Clarkston, Michigan, Forenede Stater, 48346
        • Rekruttering
        • Tanir Medical Center, PC
        • Kontakt:
        • Ledende efterforsker:
          • Narin Tanir-Avci, MD
    • Mississippi
      • Ridgeland, Mississippi, Forenede Stater, 39157
        • Rekruttering
        • Quinn Healthcare, PLLC
        • Ledende efterforsker:
          • Timothy Quinn, MD
        • Kontakt:
    • New Jersey
      • Clifton, New Jersey, Forenede Stater, 07013
        • Rekruttering
        • Gastroenterology Associates of New Jersey, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Steven Gronowitz
      • Hackensack, New Jersey, Forenede Stater, 07601
        • Aktiv, ikke rekrutterende
        • Gastroenterology Associates of New Jersey
      • Montclair, New Jersey, Forenede Stater, 07042
        • Rekruttering
        • Gastroenterology Associates of New Jersey, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Steven Gronowitz
      • Ridgewood, New Jersey, Forenede Stater, 07450
        • Rekruttering
        • Gastroenterology Associates of New Jersey, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Steven Gronowitz
      • Wayne, New Jersey, Forenede Stater, 07470
        • Rekruttering
        • Gastroenterology Associates of New Jersey, LLC
        • Kontakt:
        • Ledende efterforsker:
          • Steven Gronowitz
      • Wayne, New Jersey, Forenede Stater, 07470
        • Aktiv, ikke rekrutterende
        • Gastroenterology Associates of New Jersey
    • New York
      • Camillus, New York, Forenede Stater, 13031
        • Rekruttering
        • Associated Gastroenterologists of Central New York
        • Ledende efterforsker:
          • John Sun
        • Kontakt:
      • East Syracuse, New York, Forenede Stater, 13057
        • Rekruttering
        • Syracuse Gastroenterological Associates, P.C.
        • Ledende efterforsker:
          • Dennis Reedy
        • Kontakt:
      • Fayetteville, New York, Forenede Stater, 13066
        • Rekruttering
        • Associated Gastroenterologists of Central New York
        • Ledende efterforsker:
          • John Sun
        • Kontakt:
      • New York, New York, Forenede Stater, 10010
        • Rekruttering
        • NYU Langone
        • Kontakt:
        • Ledende efterforsker:
          • Peter Liang, MD
      • Orchard Park, New York, Forenede Stater, 14127
        • Rekruttering
        • Orchard Park Family Practice
        • Kontakt:
        • Ledende efterforsker:
          • Richard Ruh
      • Valley Stream, New York, Forenede Stater, 11581
        • Rekruttering
        • GastroCare LI
        • Ledende efterforsker:
          • Brandon Rieders
        • Kontakt:
        • Ledende efterforsker:
          • Brandon Rieders, MD
    • North Carolina
      • Cary, North Carolina, Forenede Stater, 27518
        • Rekruttering
        • Cary Gastroenterology Associates
        • Ledende efterforsker:
          • Michael Brody
        • Kontakt:
      • Chapel Hill, North Carolina, Forenede Stater, 27599
        • Rekruttering
        • University of North Carolina at Chapel Hill
        • Ledende efterforsker:
          • Sarah McGill, MD
        • Kontakt:
      • Chapel Hill, North Carolina, Forenede Stater, 27514
        • Rekruttering
        • University of North Carolina at Chapel Hill
        • Ledende efterforsker:
          • Sarah McGill, MD
        • Kontakt:
      • Hillsborough, North Carolina, Forenede Stater, 27278
        • Rekruttering
        • University of North Carolina at Chapel Hill
        • Ledende efterforsker:
          • Sarah McGill, MD
        • Kontakt:
      • Mocksville, North Carolina, Forenede Stater, 27028
        • Aktiv, ikke rekrutterende
        • Piedmont Healthcare, P.A.
      • Pinehurst, North Carolina, Forenede Stater, 28374
        • Trukket tilbage
        • Pinehurst Medical Clinic
      • Sanford, North Carolina, Forenede Stater, 27330
        • Trukket tilbage
        • Sanford Cardiology Pinehurst Medical Clinic
      • Statesville, North Carolina, Forenede Stater, 28625
        • Aktiv, ikke rekrutterende
        • Piedmont Healthcare LLC
    • Pennsylvania
      • Altoona, Pennsylvania, Forenede Stater, 16602
        • Rekruttering
        • US Digestive Health at Blair
        • Ledende efterforsker:
          • Mitul Patel
        • Kontakt:
      • Philadelphia, Pennsylvania, Forenede Stater, 19104
      • Pottstown, Pennsylvania, Forenede Stater, 19464
        • Rekruttering
        • Health Living at Pottstown Medical Specialists, Inc
        • Kontakt:
        • Ledende efterforsker:
          • Wade Brosius
    • Texas
      • Austin, Texas, Forenede Stater, 78735
        • Aktiv, ikke rekrutterende
        • Premier Family Physicians
      • Austin, Texas, Forenede Stater, 78746
        • Aktiv, ikke rekrutterende
        • Premier Family Physicians
      • Garland, Texas, Forenede Stater, 75043
        • Rekruttering
        • Broadway Medical Clinic
        • Kontakt:
        • Ledende efterforsker:
          • Mohammed Al-Haider, MD
      • Houston, Texas, Forenede Stater, 77090
        • Rekruttering
        • Integrity Advanced Therapeutics, PLLC
        • Kontakt:
        • Ledende efterforsker:
          • Howard Hamat
      • Paris, Texas, Forenede Stater, 75460
        • Rekruttering
        • Paris Family Physicians
        • Kontakt:
        • Ledende efterforsker:
          • Alois Pauls, MD
      • Shenandoah, Texas, Forenede Stater, 77384
        • Rekruttering
        • Center for Digestive Disease
        • Ledende efterforsker:
          • Shail Maheshwari
        • Kontakt:
      • Tomball, Texas, Forenede Stater, 77375
        • Rekruttering
        • Horizon Clinical Research Group
        • Ledende efterforsker:
          • Amar Dodda
        • Kontakt:
        • Ledende efterforsker:
          • Amar Dodda, MD
    • Virginia
      • Williamsburg, Virginia, Forenede Stater, 23188
        • Rekruttering
        • Tidewater Physician Multispecialty Group Clinical Research
        • Ledende efterforsker:
          • Frances Jones
        • Kontakt:

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

45 år til 81 år (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ja

Køn, der er berettiget til at studere

Alle

Prøveudtagningsmetode

Sandsynlighedsprøve

Studiebefolkning

Subjects age 45 to 81 at average risk of CRC who meet inclusion, do not meet exclusion criteria, and who successfully enroll in the study

Beskrivelse

Inclusion Criteria:

  1. Subjects aged 45-81 years at time of consent
  2. Intending to undergo a standard of care Shield test
  3. Considered by a physician or healthcare provider as being of 'average risk' for CRC; 'Average-risk' individuals in the context of CRC screening are defined as those who do not have symptoms of CRC and do not have increased risk factors for the disease (i.e., prior diagnosis of CRC, adenomatous polyps, or inflammatory bowel disease; family history of CRC or known hereditary predisposition to CRC).
  4. Subject agrees to comply with study procedures and associated standard of care assessments.

Exclusion Criteria:

  1. Undergoing colonoscopy for investigation of symptoms

  2. Personal history of colorectal cancer (CRC), adenomas, or other related cancers

  3. Family history of CRC, defined as having one or more first-degree relative (parent, sibling, or child) diagnosed with CRC at any age

  4. Positive result on another colorectal cancer screening method within the last six months, or:

    • 12 months for fecal occult blood test (FOBT) or fecal immunochemical test (FIT)
    • 36 months for FIT-DNA test

  5. Personal history of any of the following high-risk conditions for colorectal cancer:

    • Inflammatory Bowel Disease (IBD), including chronic ulcerative colitis (CUC) and Crohn's disease

    • Familial adenomatous polyposis (FAP)

    • Other hereditary cancer syndromes including but not limited to:

      • Hereditary non-polyposis colorectal cancer syndrome (HNPCC) or "Lynch Syndrome", Peutz- Jeghers Syndrome, MUTYH Polyposis (MAP), Gardner's Syndrome, Turcot's (or Crail's) Syndrome, Cowden's Syndrome, Juvenile Polyposis, Cronkhite-Canada Syndrome, Neurofibromatosis and Familial Hyperplastic Polyposis

  6. Positive Shield test result within the previous 3 years

  7. History of any malignancy (patients who have undergone surgical removal of skin squamous cell cancer may be enrolled provided the procedure was completed at least 12 months prior to the date of provision of informed consent for the study)

  8. Known diagnosis of inflammatory bowel disease

  9. Currently taking any anti-neoplastic or disease-modifying anti-rheumatic drugs (DMARDs)

  10. Any major physical trauma (e.g., disruption of tissue, surgery, organ transplant, blood product transfusion) within the 30 days leading up to the provision of informed consent

  11. Known medical condition which, in the opinion of the Investigator, should preclude enrollment into the study

  12. Participation in a clinical research study in which an experimental medication has been administered or may be administered within the 30 days leading up to providing informed consent or may be administered through the time of colonoscopy

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Observationsmodeller: COHORT
  • Tidsperspektiver: PROSPECTIVE

Kohorter og interventioner

Gruppe / kohorte
Intervention / Behandling
Enrolled Subjects

Subjects age 45 to 81 at average risk of CRC who meet inclusion, do not meet exclusion criteria, and who successfully enroll in the study.
Diagnostisk test: Shield Blood Test for colo-rectal cancer Screening

Shield Blood Test for colo-rectal cancer Screening

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Performance measures of the Shield test will be assessed for the second testing interval
Tidsramme: 33-42 Months Post-Enrollment
  • Advanced Neoplasia Specificity
  • AA Sensitivity
  • CRC Sensitivity
  • PPV for: CRC, AA, and advanced neoplasia.
  • NPV for: CRC and advanced neoplasia
33-42 Months Post-Enrollment

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Guardant Health, Inc.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

14. juli 2025

Primær færdiggørelse (Anslået)

1. september 2030

Studieafslutning (Anslået)

1. december 2030

Datoer for studieregistrering

Først indsendt

11. marts 2025

Først indsendt, der opfyldte QC-kriterier

11. marts 2025

Først opslået (Faktiske)

17. marts 2025

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

12. november 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

11. november 2026

Sidst verificeret

1. november 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 07-GI-003

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

INGEN

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Ingen

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ja

produkt fremstillet i og eksporteret fra U.S.A.

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Abonner