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Using Illusions to Boost Social Cognition (SOLLUSIONS)

19. maj 2026 opdateret af: Hôpital le Vinatier

Socio-cognitive Benefits of Exposure to Visual Illusions in Patients With Psychotic Disorders

This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relationships and daily interactions.

Main questions this study aims to answer:

  • Does dyadic exposure to complex visual objects improve mental state attribution, as measured by the Faux Pas Test?
  • Does the intervention enhance related domains of social cognition, including implicit intention inference (Hinting Task), interpretation of complex interactions (Movie for the Assessment of Social Cognition, MASC), and reduction of hostile attribution biases (Ambiguous Intentions Hostility Questionnaire, AIHQ)?
  • Are improvements maintained after one month, and do patients who receive the intervention later (waitlist group) show the same benefits once exposed?

Studieoversigt

Status

Ikke rekrutterer endnu

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

This study is a randomized, controlled, monocentric trial evaluating a novel sensory-motor rehabilitation approach for social cognition. The study is based on the hypothesis that perception is interpretative and viewpoint-dependent, and that realizing this through concrete experience could generalize to higher-level cognitive processes required for social understanding.

Participants will attend three visits and complete questionnaires and tasks that assess social understanding before and after the activity, and again one month later.

Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time. Participants will be randomized in one condition.

This research does not involve medication. It consists of simple tasks such as observing and describing visual stimuli, followed by a facilitated discussion.

Neuropsychological tests and questionnaires will be used to measure changes over time.

Expected impact: By inducing concrete perspective-shifts, the intervention aims to improve mentalizing, reduce egocentric biases, and strengthen interpretation of social cues. This bottom-up sensory-motor approach may overcome limitations of classical cognitive remediation programs by promoting deep experiential learning rather than top-down instruction.

If effective, the method may support long-term social reintegration, psychosocial functioning, and inspire wider clinical applications due to its low cost, ease of deployment, and strong ecological engagement.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

60

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Undersøgelse Kontakt Backup

Studiesteder

  • Frankrig
      • Bron, Frankrig, 69678
        • CH Le Vinatier
        • Ledende efterforsker:
          • Frédéric HAESEBAERT, MD, PhD

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ingen

Beskrivelse

Inclusion Criteria:

  • Aged 18 to 40 years
  • Fluent French speaker
  • Has provided written informed consent
  • For individuals under guardianship (curatorship): inclusion is permitted if the curator is available to assist or advise when needed.
  • Established diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, or brief psychotic disorder according to theDiagnostic and statistical manual of mental disorders (DSM-5-TR) criteria
  • Presence of social cognition impairment, defined by:subjective complaint reported by the participant or identified by care teams regarding difficulties in social interaction and clinical confirmation of observable difficulties (e.g., social withdrawal, misinterpretation of others' intentions, inappropriate social behaviour)
  • Membership or entitlement to a social security plan

Exclusion Criteria:

  • Clinical state incompatible with participation in group-based activities (e.g., severe psychomotor agitation, severe behavioural disturbance)
  • Concurrent participation in another social cognition remediation program
  • Diagnosis of intellectual disability
  • Insufficient comprehension of French for verbal interaction and test completion
  • Significant change in psychotropic medication within the past month
  • Uncorrectable visual impairment preventing participation
  • Pregnant women
  • Individuals under full guardianship (tutorship)

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Støttende pleje
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Immediate intervention
Participants receive the visual-perception session shortly after baseline assessment. They complete neurocognitive and social cognition tests before exposure, immediately after, and again at one-month follow-up.
Adfærdsmæssigt: Visual-illusion social cognition session (immediate)

A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases:

  1. For each illusion : Participants observe objects silently and draw what they see.
  2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed.
  3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation.

The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues.
Aktiv komparator: Delayed Intervention (Wait-list Control)
Participants complete the same assessments as Arm 1 but receive the intervention only after a waiting period. This arm allows comparison between natural progression and workshop effects prior to exposure.
Adfærdsmæssigt: Visual-illusion social cognition session (delayed)
A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases: 1. For each illusion : Participants observe objects silently and draw what they see. 2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed. 3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation. The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. Delivered after a delay following baseline assessment.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
"Faux Pas" test total score
Tidsramme: Change from pre to post intervention (up to 3 hours)
  1. Total of correctly recognised "Faux Pas" Score range : 0 - 30 Minimum (0) : no correct detection of faux pas Maximum (30) : all faux pas correctly detected
  2. Total of identified absence of "Faux Pas" Score range : 0 - 10 Minimum (0) : incorrectly identifies absence of faux pas Maximum (10) : correctly identifies absence of faux pas
  3. Total score of control question comprehension Score range : 0 - 20 Minimum (0) : poor comprehension Maximum (20) : Full comprehension
Change from pre to post intervention (up to 3 hours)

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Hinting Task
Tidsramme: Change from pre to post intervention (up to 3 hours)
  1. Number of correctly inferred items with hint 1 Score range : 0 - 20 Minimum (0) : No correct inference of intentions Maximum (20) : All intentions correctly inferred
  2. Number of correctly inferred items with hint 2 Score range : 0 - 20 Minimum (0) : No correct inference of intentions Maximum (20) : All intentions correctly inferred
Change from pre to post intervention (up to 3 hours)
MASC performance
Tidsramme: Change from pre intervention to follow-up session (up to a month and a half)
Number of correct responses Score range 0 - 45 Minimum (0) : No correct mental state inference Maximum (45) : All mental states correctly inferred
Change from pre intervention to follow-up session (up to a month and a half)

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Hôpital le Vinatier

Samarbejdspartnere

INSERM 1028

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Anslået)

1. juli 2026

Primær færdiggørelse (Anslået)

1. januar 2029

Studieafslutning (Anslået)

1. februar 2029

Datoer for studieregistrering

Først indsendt

12. maj 2026

Først indsendt, der opfyldte QC-kriterier

19. maj 2026

Først opslået (Faktiske)

22. maj 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

22. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

19. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 2025-A02057-42

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

JA

IPD-planbeskrivelse

Anonymized IPD that underlie results in a publication may be shared upon reasonable scientific request following publication of study results.

IPD-delingstidsramme

IPD available after publication of primary results

IPD-delingsadgangskriterier

Requests must be made by qualified researchers for scientific purposes. Data will be shared under controlled access agreement ensuring privacy and ethical standards.

IPD-deling Understøttende informationstype

  • STUDY_PROTOCOL
  • SAP

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