Questa pagina è stata tradotta automaticamente e l'accuratezza della traduzione non è garantita. Si prega di fare riferimento al Versione inglese per un testo di partenza.

Effect of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke

1 giugno 2026 aggiornato da: Riphah International University

Effect of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke Survivors

This Randomized Controlled Trial is conducted to investigate the effects of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke Survivors.

Panoramica dello studio

Stato

Non ancora reclutamento

Condizioni

Intervento / Trattamento

Descrizione dettagliata

Strokes are a leading cause of long-term disability worldwide because they frequently result in significant impairments in both cognitive and physical abilities. Traditional rehabilitation methods have primarily focused on single-task training, which targets motor or cognitive processes separately. However, the complex demands of daily tasks, which often require simultaneous cognitive and physical processing, may be too much for these approaches to handle. Cognitive-motor dual-task training (CMDT), which blends cognitive tasks with motor activities, has emerged as a promising rehabilitation method to more accurately mimic real-world scenarios. This approach blends a cognitive task, like problem-solving or attention-demanding activities, with a physical task, like walking or balancing exercises. By enhancing the brain's ability to manage multiple tasks simultaneously, CMDT aims to improve the cognitive and motor outcomes of stroke patients.

It has been demonstrated that dual-tasking increases activity in the prefrontal cortex, a region of the brain related to executive function and attention, which is crucial for managing several tasks at once. By stimulating these brain networks, CMDT may improve neuroplasticity and functional remodelling, which may lead to better postural control and mobility recovery. CMDT is based on two neurophysiological processes: enhanced synaptic plasticity and increased expression of brain-derived neurotrophic factor (BDNF). When cognitive and motor tasks are carried out simultaneously, these mechanisms support synaptogenesis and neuroprotection. Despite the growing body of evidence supporting CMDT, more research is still needed to enhance training techniques, understand the mechanisms behind its effects, and evaluate long-term outcomes. Recent meta-analyses have shown that CMDT therapies result in long-lasting cognitive improvements, including improvements in working memory, cognitive flexibility, and executive function all of which are essential for functional independence. In comparison to single-task training, recent RCTs have shown that CMDT improves quality of life while also improving upper extremity and cognitive performance. Dual-task therapies that include activities of daily living promote motivation and active engagement, leading to significant improvements in functional ability and life satisfaction.

Tipo di studio

Interventistico

Iscrizione (Stimato)

28

Fase

  • Non applicabile

Contatti e Sedi

Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.

Contatto studio

Luoghi di studio

  • Pakistan
    • Punjab Province
      • Chak One Hundred Fifty-seven, Punjab Province, Pakistan
        • Family Diagnostic Center
        • Contatto:
        • Contatto:
        • Sub-investigatore:
          • Abrish H Abbasi, PhD* Rehab
        • Investigatore principale:
          • Muattar Hina, MS-NMPT*

Criteri di partecipazione

I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.

Criteri di ammissibilità

Età idonea allo studio

  • Adulto
  • Adulto più anziano

Accetta volontari sani

Sì

Descrizione

Inclusion Criteria:

  • Age between 40-75 years.
  • Clinically diagnosed ischemic or hemorrhagic stroke (≥3 months,post-onset).
  • Ability to follow verbal commands (MMSE≥24).
  • Medically stable and cleared for physical activity.
  • Able to walk independently or with minimal assistance (Functional Ambulation Categories ≥3)
  • Berg Balance Scale score between 21-45 (indicating moderate fall risk).

Exclusion Criteria:

  • Severe aphasia or language deficits impacting task comprehension.
  • Severe spasticity (modified Ashworth scale ≥2 in lower limbs).
  • Visual or vestibular impairments affecting balance.
  • Severe musculoskeletal conditions or orthopedic impairments that limit safe participation in balance and gait training. (e.g. recent fractures , severe arthritis).
  • Diagnosed Dementia or neurodegenerative disorders
  • Participation in any other structured dual-task or cognitive training program within the past 3 months

Piano di studio

Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.

Come è strutturato lo studio?

Dettagli di progettazione

  • Scopo principale: Trattamento
  • Assegnazione: Randomizzato
  • Modello interventistico: Assegnazione parallela
  • Mascheramento: Separare

Armi e interventi

Gruppo di partecipanti / Arm
Intervento / Trattamento
Sperimentale: Cognitive-motor dual-task training (CMDT) Group
Cognitive-motor dual-task training (CMDT) conducted three times weekly for 45-60 minutes with 10 repetitions each task over 6 weeks progressively challenges stroke survivors with static and dynamic tasks in weeks 1-2, anticipatory tasks in weeks 3-4, and reactive tasks in weeks 5-6, integrating cognitive challenges such as verbal fluency, Stroop tests, and auditory reactions with motor activities like walking and balance exercises
Altro: Cognitive-motor dual-task training (CMDT) Group
Cognitive-motor dual-task training (CMDT) conducted three times weekly for 45-60 minutes with 10 repetitions each task over 6 weeks progressively challenges stroke survivors with static and dynamic tasks in weeks 1-2, anticipatory tasks in weeks 3-4, and reactive tasks in weeks 5-6, integrating cognitive challenges such as verbal fluency, Stroop tests, and auditory reactions with motor activities like walking and balance exercises
Comparatore attivo: Conventional Balance Training
Static and dynamic balance exercises without cognitive load, e.g., standing and shifting weight, conducted three times weekly for 45-60 minutes with 10 repetitions each task over 6 weeks progressively challenges stroke survivors with static and dynamic tasks in weeks 1-2, anticipatory tasks in weeks 3-4, and reactive tasks in weeks 5-6.
Altro: Conventional Balance Training
Static and dynamic balance exercises without cognitive load, e.g., standing and shifting weight, conducted three times weekly for 45-60 minutes with 10 repetitions each task over 6 weeks progressively challenges stroke survivors with static and dynamic tasks in weeks 1-2, anticipatory tasks in weeks 3-4, and reactive tasks in weeks 5-6.

Cosa sta misurando lo studio?

Misure di risultato primarie

Misura del risultato
Misura Descrizione
Lasso di tempo
Berg Balance Scale(BBS)
Lasso di tempo: 6 weeks

A clinical tool used to assess static and dynamic balance through 14 functional tasks. Tasks include sitting, standing, reaching, turning, and single-leg stance. It evaluates a person's ability to maintain balance during common daily activities and helps determine the risk of falls, especially in stroke patients and older adults.

Scoring: Each item is scored from 0 to 4 (maximum score: 56)

  • Low fall risk: 41-56
  • Moderate fall risk: 21-40
  • High fall risk: 0-20
6 weeks
Timed-Up and Go Test
Lasso di tempo: 6 weeks

A simple test used to assess mobility, balance, walking ability, and fall risk. The participant is timed while standing up from a chair, walking 3 meters, turning around, walking back, and sitting down. Scoring: Time recorded in seconds

  • <10 sec: Normal mobility
  • 10-20 sec: Good mobility, mostly independent
  • >20 sec: Limited mobility, may require assistance
6 weeks
Postural Assessment Scale (PASS)
Lasso di tempo: 6 weeks
A stroke-specific tool used to assess postural control in lying, sitting, and standing positions. It includes 12 items that evaluate the ability to maintain or change postures. Scoring: Each item scored 0-3 (Total score: 36) Higher scores indicate better postural control.
6 weeks
Dual Task Cost (DTC)
Lasso di tempo: 6 weeks

Quantifies the impact of performing a cognitive task on motor performance (e.g., gait or balance). Calculated as:

DTC(%)= Single-task performance-Dual-task performance×100 Higher DTC values indicate greater dual-task interference and poorer ability to manage simultaneous cognitive and motor demands.
6 weeks

Collaboratori e investigatori

Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.

Sponsor

Riphah International University

Investigatori

  • Investigatore principale: Muattar Hina, MS-NMPT*, Riphah International Unversity

Studiare le date dei record

Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.

Studia le date principali

Inizio studio (Stimato)

20 maggio 2026

Completamento primario (Stimato)

20 ottobre 2026

Completamento dello studio (Stimato)

20 novembre 2026

Date di iscrizione allo studio

Primo inviato

1 giugno 2026

Primo inviato che soddisfa i criteri di controllo qualità

1 giugno 2026

Primo Inserito (Effettivo)

5 giugno 2026

Aggiornamenti dei record di studio

Ultimo aggiornamento pubblicato (Effettivo)

5 giugno 2026

Ultimo aggiornamento inviato che soddisfa i criteri QC

1 giugno 2026

Ultimo verificato

1 giugno 2026

Maggiori informazioni

Termini relativi a questo studio

Parole chiave

Termini MeSH pertinenti aggiuntivi

Altri numeri di identificazione dello studio

  • 02269/ Muattar Hina

Piano per i dati dei singoli partecipanti (IPD)

Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?

NO

Informazioni su farmaci e dispositivi, documenti di studio

Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti

No

Studia un dispositivo regolamentato dalla FDA degli Stati Uniti

No

Queste informazioni sono state recuperate direttamente dal sito web clinicaltrials.gov senza alcuna modifica. In caso di richieste di modifica, rimozione o aggiornamento dei dettagli dello studio, contattare register@clinicaltrials.gov. Non appena verrà implementata una modifica su clinicaltrials.gov, questa verrà aggiornata automaticamente anche sul nostro sito web .

Prove cliniche su Cognitive-motor dual-task training (CMDT) Group

Cerca prove simili

Sponsor e collaboratori

Condizioni mediche

Interventi farmacologici

CROs by country

CROs in Kyrgyzstan

Condizioni

Malattie rare

Interventi farmacologici

Supplementi dietetici

Sponsor / Collaboratori

Sedi

Sottoscrivi