Effects of Different High-Intensity Interval Training Protocols on Physiological and Skeletal Muscle Adaptations in Healthy Young Men
This study investigated the effects of different high-intensity interval training protocols on physical fitness and physiological adaptations in healthy young men.
Participants underwent a two-week exercise training program consisting of six sessions performed three times per week. Four training protocols were investigated, differing in exercise intensity, duration of exercise bouts, and recovery periods.
The primary outcome was the change in maximal oxygen uptake (VO2max), an indicator of aerobic fitness. Additional assessments included cognitive performance, measured using tests of attention, processing speed, and inhibitory control, as well as selected physiological and skeletal muscle adaptations.
The study aimed to improve understanding of how different high-intensity interval training protocols influence aerobic fitness and other physiological responses over a short training period.
調査の概要
状態
状態
条件
条件
介入・治療
介入・治療
詳細な説明
High-intensity interval training (HIIT) and sprint interval training (SIT) are exercise strategies characterized by repeated bouts of vigorous or maximal exercise interspersed with recovery periods. These training approaches may induce physiological adaptations within relatively short intervention periods. However, the effects of different combinations of exercise duration, intensity, and recovery time on aerobic fitness, cognitive performance, and skeletal muscle adaptations require further investigation.
This interventional study examined physiological responses to four cycling-based high-intensity training protocols in healthy young men. Participants completed six training sessions over two weeks, with three sessions performed each week.
The investigated protocols included:
SIT10:1: Repeated 10-second maximal cycling sprints separated by 60-second recovery periods.
SIT10:4: Repeated 10-second maximal cycling sprints separated by 240-second recovery periods.
HIIT90:180: Six 90-second cycling intervals performed at 80% of maximal aerobic power, separated by 180-second passive recovery periods.
Wingate-SIT: Repeated 30-second all-out cycling sprints using a Wingate-based protocol.
The primary outcome was the change in maximal oxygen uptake (VO2max), assessed using incremental exercise testing before and after the intervention. Additional assessments included cognitive performance using the Stroop Color-Word Test, Trail Making Test, and Digit Span Test, as well as selected measures of exercise performance and skeletal muscle metabolic adaptations.
Skeletal muscle biopsies were collected from subsets of participants before and after training to investigate exercise-induced adaptations in muscle tissue. Stored biopsy samples were subsequently used for exploratory proteomic analyses.
The study was designed to characterize short-term physiological and skeletal muscle responses to different high-intensity interval exercise protocols.
研究の種類
研究の種類
入学 (実際)
入学
段階
段階
- 適用できない
連絡先と場所
研究場所
-
-
Pomeranian
-
Gdansk、Pomeranian、ポーランド、80-336
- Gdansk University of Physical Education and Sport
-
-
参加基準
適格基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
Healthy adult males. Physically active individuals. Ability to perform high-intensity cycling exercise. Willingness to participate in the two-week training intervention and complete the required assessments.
Provision of written informed consent.
Exclusion Criteria:
Known cardiovascular, respiratory, metabolic, or neurological disorders that could affect exercise performance or participant safety.
Musculoskeletal injuries or conditions preventing participation in high-intensity cycling exercise.
Medical contraindications to maximal exercise testing or sprint interval training.
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：非ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
アーム数
武器と介入
参加者グループ / アーム参加者グループ / アーム |
介入・治療介入・治療 |
|---|---|
|
実験的：SIT10:1 - Short-Recovery Sprint Interval Training
Participants completed a two-week cycling sprint interval training program comprising six sessions (three sessions per week). The protocol involved repeated 10-second maximal cycling sprints separated by 60-second recovery intervals. |
A two-week cycling sprint interval training intervention consisting of six sessions performed three times per week. Participants performed repeated 10-second maximal cycling sprints interspersed with 60-second recovery intervals. |
|
実験的：SIT10:4 - Long-Recovery Sprint Interval Training
Participants completed a two-week cycling sprint interval training program comprising six sessions (three sessions per week). The protocol involved repeated 10-second maximal cycling sprints separated by 240-second recovery intervals. |
A two-week cycling sprint interval training intervention consisting of six sessions performed three times per week. Participants performed repeated 10-second maximal cycling sprints interspersed with 240-second recovery intervals. |
|
実験的：HIIT90:180 - High-Intensity Interval Training
Participants completed a two-week high-intensity interval cycling program consisting of six supervised training sessions (three sessions per week). Each session included six 90-second cycling bouts performed at 80% of maximal aerobic power, separated by 180-second passive recovery intervals. Exercise cadence was maintained at approximately 60 revolutions per minute. |
A two-week cycling high-intensity interval training intervention comprising six supervised sessions performed three times per week. Each session consisted of six 90-second exercise bouts at 80% of maximal aerobic power, separated by 180-second passive recovery intervals. Cycling cadence was approximately 60 revolutions per minute. |
|
実験的：Wingate-SIT - Wingate-Based Sprint Interval Training
Participants completed a two-week sprint interval training program comprising six cycling sessions (three sessions per week). The intervention consisted of repeated 30-second all-out cycling sprints performed using a Wingate-based protocol, with recovery periods between successive efforts. |
A two-week cycling sprint interval training intervention comprising six sessions performed three times per week. Participants performed repeated 30-second all-out cycling sprints using a Wingate-based protocol, with recovery intervals between successive sprints. |
この研究は何を測定していますか？
主要な結果の測定
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Change in Maximal Oxygen Uptake (VO2max)
時間枠：Baseline and after the 2-week training intervention
|
Change in maximal oxygen uptake (VO2max), expressed in mL/kg/min, assessed using an incremental exercise test before and after the two-week training intervention. |
Baseline and after the 2-week training intervention
|
二次結果の測定
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Change in Cognitive Performance
時間枠：Baseline and after the 2-week training intervention
|
Changes in cognitive performance assessed using the Stroop Color-Word Test (inhibitory control), Trail Making Test (processing speed and executive function), and Digit Span Test (working memory), before and after the two-week training intervention. |
Baseline and after the 2-week training intervention
|
|
Change in Skeletal Muscle Oxidative Enzyme Activity
時間枠：Baseline and after the 2-week training intervention
|
Changes in skeletal muscle oxidative enzyme activity assessed in biopsy samples collected before and after the two-week training intervention. Muscle biopsies were performed in a subset of participants who provided additional informed consent for the procedure. |
Baseline and after the 2-week training intervention
|
協力者と研究者
研究記録日
主要日程の研究
研究開始 (実際)
研究開始
一次修了 (実際)
一次修了
研究の完了 (実際)
研究の完了
試験登録日
最初に提出
最初に提出
QC基準を満たした最初の提出物
QC基準を満たした最初の提出物
最初の投稿 (実際)
最初の投稿
学習記録の更新
投稿された最後の更新 (実際)
投稿された最後の更新
QC基準を満たした最後の更新が送信されました
QC基準を満たした最後の更新が送信されました
最終確認日
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
その他の研究ID番号
- AWFiS/2026_5_RL
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
IPD プランの説明
Individual participant data will not be made publicly available due to participant confidentiality considerations and the absence of a data-sharing plan in the original study protocol.
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。