このページは自動翻訳されたものであり、翻訳の正確性は保証されていません。を参照してください。 英語版 ソーステキスト用。

The CARE Program: CAncer REhabilitation Pilot Study for Older Adults (CARE Program)

2017年9月11日 更新者：UNC Lineberger Comprehensive Cancer Center

LCCC 1409: The CARE Program: CAncer REhabilitation Pilot Study for Older Adults

The CARE Program is a randomized trial of a cancer rehabilitation program designed to help older cancer patients who have shown to have a loss of function.

調査の概要

状態

完了

条件

介入・治療

詳細な説明

This is a prospective, two-arm, single-center randomized controlled pilot trial of a cancer rehabilitation program for older adults, titled the 'CARE program,' which is designed to maintain and/or improve functional status and quality of life in older adults diagnosed with cancer. Adults aged 65 years and older with cancer will be screened with a Geriatric Assessment (GA) for eligibility. Although breast cancer patients will be eligible, this study will focus primarily on other types of cancers. Adults with at least one functional deficit --defined as impairment in ability to perform activities of daily living or instrumental activities of daily living, cognitive decline or balance -- will be randomized to either the intervention (CARE program) or to the control arm (Supportive care services information only). Both arms will receive a brochure about the supportive care program to provide patients who we've identified as having deficits with information about auxiliary services available and because the intent is to limit the difference between the groups. We hypothesize that patients who participate in the CARE program will maintain or improve functional status and quality of life when compared to supportive care services information only.

研究の種類

介入

入学 (実際)

67

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究場所

  • アメリカ
    • North Carolina
      • Chapel Hill、North Carolina、アメリカ、27599
        • University of North Carolina

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

65年歳以上 (高齢者)

健康ボランティアの受け入れ

いいえ

受講資格のある性別

女性

説明

Inclusion Criteria:

  • Aged 65 years or older
  • Has an outpatient appointment within UNC Chapel Hill Lineberger Comprehensive Cancer Center
  • Diagnosis of cancer within last two years.
  • Has a life expectancy of 12 months or longer. All cancer types are included.
  • English speaking
  • Willing to complete the UNC GA
  • Has at least one functional deficit as defined by GA screen
  • Understands study design, risks, and benefits and have signed informed consent
  • Willing to be randomized into either study arm
  • Ability to safely participate in outpatient rehabilitation program

Exclusion Criteria:

  • Unable to safely participate in outpatient rehabilitation.
  • Currently receiving rehabilitation.
  • Any participant who has urologic cancer or is enrolled in a competing trial.

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか？

デザインの詳細

  • 主な目的：支持療法
  • 割り当て：ランダム化
  • 介入モデル：単一グループの割り当て
  • マスキング：なし（オープンラベル）

武器と介入

参加者グループ / アーム
介入・治療
実験的：CARE Intervention
This group will be contacted to make an appointment for outpatient Occupational and Physical therapy. The therapist will determine the type, frequency and length of treatment. Follow up phone calls will be made to ensure appointments are made, kept and rescheduled as needed.
他の：Occupational and Physical Therapy
OT and PT will be arranged for the subject and conducted in a manner as determined by the therapist.
介入なし：CARE Control
Patients randomized to this arm will receive contact information and a brochure outlining the services available within the supportive care program. The study coordinator will provide the information based on their results and assist the patient with contacting the program if desired.

この研究は何を測定していますか？

主要な結果の測定

結果測定
メジャーの説明
時間枠
To measure the change in Nottingham Extended Activities of Daily Living (NEADL) score from baseline to three months.
時間枠：3 months
Compare the change in NEADL scores from baseline to 3 months between patients who receive the CARE program (intervention) and those in the control arm.
3 months

二次結果の測定

結果測定
メジャーの説明
時間枠
To measure the change in Activities of Daily Living from Baseline and 2 months
時間枠：2 months
As measured by the Geriatric Assessment
2 months
To measure the change in Activities of Daily Living from Baseline and 3 months
時間枠：3 months
As measured by the Geriatric Assessment
3 months
To measure the change in physical health from Baseline and 3 months
時間枠：3 months
As measured by the Geriatric Assessment
3 months
To measure the change in physical health from Baseline and 2 months
時間枠：2 months
As measured by the Geriatric Assessment
2 months
To measure the change in quality of life from Baseline and 2 months
時間枠：2 months
As measured by the PROMIS assessment
2 months
To measure the change in quality of life from Baseline and 3 months
時間枠：3 months
As measured by the PROMIS assessment
3 months
To measure the change in internalized occupational possibilities from Baseline and 3 months
時間枠：3 months
As measured by the Possibilities for Activity Scale (PActS)
3 months
To measure the change in internalized occupational possibilities from Baseline and 2 months
時間枠：2 months
As measured by the Possibilities for Activity Scale (PActS)
2 months
To measure the change in cognitive function from Baseline and 2 months
時間枠：2 months
As measured by the Blessed Memory Orientation Concentration test
2 months
To measure the change in cognitive function from Baseline and 3 months
時間枠：3 months
As measured by the Blessed Memory Orientation Concentration test
3 months
To measure the feasibility of the CARE Program
時間枠：3 months
To describe the feasibility of the CARE program by reporting enrollment and retention as defined by (1) percent eligible who agree to participate (2) percent in each group that completed follow-up measures at 2 and 3 months and (3) percent of patients in CARE program who go to 70% of appointments.
3 months
To measure the change in balance over the course of the study
時間枠：3 months
Intervention Group Only: As measured by the Berg Balance Scale
3 months
To measure the change in upper extremity use and ability over the course of the study
時間枠：3 months
Intervention Group Only: As measured by the Disability of the Arm, Shoulder and Hand scale
3 months
To measure the change in cognition over the course of the study
時間枠：3 months
Intervention Group Only: As measured by the Montreal Cognitive Assessment
3 months
To measure the change in dynamic gait ability over the course of the study
時間枠：3 months
Intervention Group Only: As measured by the Dynamic Gait Index
3 months
To measure satisfaction with the CARE Program
時間枠：3 months
To evaluate the program a short interview will be completed with CARE team to determine what worked well, what didn't and suggested changes/improvements for CARE program after completion of project.
3 months

協力者と研究者

ここでは、この調査に関係する人々や組織を見つけることができます。

スポンサー

UNC Lineberger Comprehensive Cancer Center

捜査官

  • 主任研究者：Mackenzi Pergolotti, PhD、Colorado State University

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始 (実際)

2014年6月1日

一次修了 (実際)

2017年3月1日

研究の完了 (実際)

2017年3月1日

試験登録日

最初に提出

2014年12月1日

QC基準を満たした最初の提出物

2014年12月2日

最初の投稿 (見積もり)

2014年12月3日

学習記録の更新

投稿された最後の更新 (実際)

2017年9月12日

QC基準を満たした最後の更新が送信されました

2017年9月11日

最終確認日

2017年9月1日

詳しくは

本研究に関する用語

キーワード

その他の研究ID番号

  • LCCC1409
  • 14-1159 (その他の識別子：University of North Carolina IRB)

この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。

癌の臨床試験

  • Jonsson Comprehensive Cancer Center
    National Cancer Institute (NCI); Highlight Therapeutics
    積極的、募集していない
    切除可能な軟部肉腫の治療のための手術前のニボルマブと BO-112
    平滑筋肉腫 | 悪性末梢神経鞘腫瘍 | 滑膜肉腫 | 未分化多形肉腫 | 骨の未分化高悪性度多形肉腫 | 粘液線維肉腫 | II期の体幹および四肢の軟部肉腫 AJCC v8 | III期の体幹および四肢の軟部肉腫 AJCC v8 | IIIA 期の体幹および四肢の軟部肉腫 AJCC v8 | IIIB 期の体幹および四肢の軟部肉腫 AJCC v8 | 切除可能な軟部肉腫 | 多形性横紋筋肉腫 | 切除可能な脱分化型脂肪肉腫 | 切除可能な未分化多形肉腫 | 軟部組織線維肉腫 | 紡錘細胞肉腫 | ステージ I 後腹膜肉腫 AJCC (American Joint Committee on Cancer) v8 | 体幹および四肢の I 期軟部肉腫 AJCC v8 | ステージ... およびその他の条件
    アメリカ

Occupational and Physical Therapyの臨床試験

類似の治験を検索

スポンサーと協力者

医学的状態

薬物療法

CROs by country

CROs in Serbia

条件

まれな病気

薬物療法

ダイエットサプリメント

スポンサー/協力者

場所

3
購読する