Appropriateness of Intravenous Antibiotics Prescriptions at Hospital Discharge
Quasi-experimental Study Comparing Intravenous Antibiotics Prescriptions at Hospital Discharge With and Without ID Consultation
調査の概要
詳細な説明
The pre-intervention period was started from November 1, 2015 to April 30, 2016 (6-month period), in which the intravenous antibiotics at hospital discharge were prescribed by the primary care team. The post-intervention period was started from May 1, 2016 to February 28, 2017 (10-month period), in which the intravenous antibiotics at hospital discharge were reviewed and intervened by ID team.
The appropriateness of intravenous antibiotics was assessed separately by the ID fellow and ID specialist. If disagreement occurred, the feedback to the ID fellow was performed and the decision by ID specialist was used in the final analysis of appropriateness.
In post-intervention period, ID fellow modified the intravenous antibiotics ordered by the primary team if those intravenous antibiotics were judged as inappropriate by ID fellow as follows: 1) discontinue intravenous antibiotics (treatment was complete), 2) switch to oral antibiotics, 3) change intravenous antibiotics to cover isolated pathogens, 4) adjust the dose of intravenous antibiotics, and 5) change the duration of intravenous antibiotics
Finally, ID specialist retrospectively assessed the appropriateness of intravenous antibiotics at hospital discharge managed by ID fellow in post-intervention period.
研究の種類
入学 (実際)
段階
- 適用できない
連絡先と場所
研究場所
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-
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Chiang Mai、タイ、50200
- Department of Medicine
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
All adult patients who met the following criteria were consecutively enrolled;
- age≥ 15 years old and
- had infections at any sites and received intravenous antibiotics.
Exclusion Criteria:
- They were evaluated by infectious diseases specialist for appropriate antibiotics during admission
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：ヘルスサービス研究
- 割り当て：非ランダム化
- 介入モデル：順次割り当て
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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介入なし：pre-intervention period
The charts of patients who were prescribed intravenous antibiotics at hospital discharge were reviewed.
Appropriateness of intravenous antibiotics was assessed by ID specialists.
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実験的：post-intervention period
The intervention is the charts of patients who were prescribed intravenous antibiotics at hospital discharge by the primary team were prospectively reviewed and intervened by ID team (ID specialist approval)
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Appropriateness of intravenous antibiotics ordered by the primary team was assessed by ID specialist.
ID fellow modified the intravenous antibiotics ordered by the primary team if those intravenous antibiotics were judged as inappropriate by ID fellow as follows: 1) discontinue intravenous antibiotics (treatment was complete), 2) switch to oral antibiotics, 3) change intravenous antibiotics to cover isolated pathogens, 4) adjust the dose of intravenous antibiotics, and 5) change the duration of intravenous antibiotics.
Finally, ID specialist retrospectively assessed the appropriateness of intravenous antibiotics at hospital discharge managed by ID fellow in post-intervention period.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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The proportion of appropriateness of intravenous antibiotics prescriptions at hospital discharge between groups
時間枠：16 months
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To calculate the number of antibiotic prescriptions at hospital discharge over the total number of prescriptions, comparing between pre-and post-intervention period.
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16 months
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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The costs of antibiotics for the course of treatment
時間枠：16 months
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To compare the cost of antibiotics for the course of treatment between the 2 periods
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16 months
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Clinical improvement at 1 week
時間枠：1 week
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To calculate the number of patients who had clinical improvement at 1 week over the total number of patients in each period, comparing between the 2 periods
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1 week
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Readmission within 30 days, length of hospital stay
時間枠：30 days
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To calculate the number of patients who were readmitted within 30 days over the total number of patients in each period, comparing between the 2 periods
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30 days
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Length of hospital stay
時間枠：60 days
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To calculate the length of hospital stays in days between 2 periods
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60 days
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協力者と研究者
スポンサー
捜査官
- 主任研究者：Romanee Chaiwarith, MD、Maharaj Nakorn Chiang Mai Hospital
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
その他の研究ID番号
- 3631
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
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ID specialist approvalの臨床試験
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Queen's University, BelfastUniversity of Sheffield; University of Glasgow; University of South Wales; Baily Thomas Charitable...募集
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Children's Hospital of PhiladelphiaUniversity of Pennsylvania完了
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Children's Hospital of PhiladelphiaUniversity of Pennsylvania完了