Appropriateness of Intravenous Antibiotics Prescriptions at Hospital Discharge
Quasi-experimental Study Comparing Intravenous Antibiotics Prescriptions at Hospital Discharge With and Without ID Consultation
연구 개요
상세 설명
The pre-intervention period was started from November 1, 2015 to April 30, 2016 (6-month period), in which the intravenous antibiotics at hospital discharge were prescribed by the primary care team. The post-intervention period was started from May 1, 2016 to February 28, 2017 (10-month period), in which the intravenous antibiotics at hospital discharge were reviewed and intervened by ID team.
The appropriateness of intravenous antibiotics was assessed separately by the ID fellow and ID specialist. If disagreement occurred, the feedback to the ID fellow was performed and the decision by ID specialist was used in the final analysis of appropriateness.
In post-intervention period, ID fellow modified the intravenous antibiotics ordered by the primary team if those intravenous antibiotics were judged as inappropriate by ID fellow as follows: 1) discontinue intravenous antibiotics (treatment was complete), 2) switch to oral antibiotics, 3) change intravenous antibiotics to cover isolated pathogens, 4) adjust the dose of intravenous antibiotics, and 5) change the duration of intravenous antibiotics
Finally, ID specialist retrospectively assessed the appropriateness of intravenous antibiotics at hospital discharge managed by ID fellow in post-intervention period.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Chiang Mai, 태국, 50200
- Department of Medicine
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
All adult patients who met the following criteria were consecutively enrolled;
- age≥ 15 years old and
- had infections at any sites and received intravenous antibiotics.
Exclusion Criteria:
- They were evaluated by infectious diseases specialist for appropriate antibiotics during admission
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 건강 서비스 연구
- 할당: 무작위화되지 않음
- 중재 모델: 순차적 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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간섭 없음: pre-intervention period
The charts of patients who were prescribed intravenous antibiotics at hospital discharge were reviewed.
Appropriateness of intravenous antibiotics was assessed by ID specialists.
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실험적: post-intervention period
The intervention is the charts of patients who were prescribed intravenous antibiotics at hospital discharge by the primary team were prospectively reviewed and intervened by ID team (ID specialist approval)
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Appropriateness of intravenous antibiotics ordered by the primary team was assessed by ID specialist.
ID fellow modified the intravenous antibiotics ordered by the primary team if those intravenous antibiotics were judged as inappropriate by ID fellow as follows: 1) discontinue intravenous antibiotics (treatment was complete), 2) switch to oral antibiotics, 3) change intravenous antibiotics to cover isolated pathogens, 4) adjust the dose of intravenous antibiotics, and 5) change the duration of intravenous antibiotics.
Finally, ID specialist retrospectively assessed the appropriateness of intravenous antibiotics at hospital discharge managed by ID fellow in post-intervention period.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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The proportion of appropriateness of intravenous antibiotics prescriptions at hospital discharge between groups
기간: 16 months
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To calculate the number of antibiotic prescriptions at hospital discharge over the total number of prescriptions, comparing between pre-and post-intervention period.
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16 months
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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The costs of antibiotics for the course of treatment
기간: 16 months
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To compare the cost of antibiotics for the course of treatment between the 2 periods
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16 months
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Clinical improvement at 1 week
기간: 1 week
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To calculate the number of patients who had clinical improvement at 1 week over the total number of patients in each period, comparing between the 2 periods
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1 week
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Readmission within 30 days, length of hospital stay
기간: 30 days
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To calculate the number of patients who were readmitted within 30 days over the total number of patients in each period, comparing between the 2 periods
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30 days
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Length of hospital stay
기간: 60 days
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To calculate the length of hospital stays in days between 2 periods
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60 days
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공동 작업자 및 조사자
수사관
- 수석 연구원: Romanee Chaiwarith, MD, Maharaj Nakorn Chiang Mai Hospital
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- 3631
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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