Oral Findings in a Group of Egyptian Pediatric Patients at Endstage Renal Disease
Oral Findings in a Group of Egyptian Pediatric Patients at Endstage Renal Disease Either on Haemodialysis or After Renal Transplantation
調査の概要
詳細な説明
Study setting:
- The study will be held at the center of Pediatric Nephrology and transplantation, El- Mounira children's hospital (Abu El rish).
- The data collected through the questionnaire will be obtained through an interview between the investigator and the parent or the legal guardian that's based on WHO guide for health surveys(WHO Oral health surveys, 2013)
- For patients undergoing dialysis, examination will be performed at the dialysis unit during dialysis session (there is no waiting room for patients before dialysis).
- For patients who received renal transplantation, examination will be performed at the outpatient nephrology clinic during follow up visits.
- Clinical examination will be performed for both oral (soft tissue) and dental (hard) tissue.
- Decayed-Missing-Filled Index ( DMF ) which was introduced by Klein, Palmer and Knutson in 1938 and modified by WHO.
The components are:
D component:
Used to describe (Decayed teeth) which include:
Carious tooth. Filled tooth with recurrent decay. Only the roots are left. Defect filling with caries. Temporary filling. Filled tooth surface with other surface decayed.
M component:
Used to describe (Missing teeth due to caries) other cases should be excluded.
F component:
Used to describe (Filled teeth due to caries). Teeth were considered filled without decay when one or more permanent restorations were present and there was no secondary (recurrent) caries or other area of the tooth with primary caries. A tooth with a crown placed because of previous decay was recorded in this category. Teeth stored for reason other than dental caries should be excluded.
deft / defs , which was introduced by Gruebbel in 1944
d- decayed tooth . e- decayed tooth indicated for extraction . f- filled tooth
• The coding system for the Modified DDE Index has three items of information that will be recorded for each tooth surface. (Clarkson and O'Mullane, 1989)
First, the Type of Defect, codes 0-7, was recorded. Then the Sub-type of that defect was noted, i.e., when a demarcated opacity was present, the Sub-type was either white/cream (code 1) or yellow/brown (code 2), or when a diffuse opacity was present, then six options were possible. Finally, the extent of each defect was recorded. The new additional sub-type (code 3) termed "diffuse confluent opacity" is defined as a diffuse opacity in which any patchiness has merged into a regular condensed chalky white area, and it could cover the entire surface of a tooth or be confined to a localized area of the tooth surface.
- Oral candidiasis assessment will be based on the Lehner scale (Cleverson et al., 2014)
- In assessing the degree of gingival hyperplasia we will use the index of Angelopoulos and Goaz, described by Prof. T. Djemileva. (Dencheva et al., 2011)
研究の種類
入学 (予想される)
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Pediatric patients <15 years old with a diagnosis of end stage renal disease "stage 5" receiving dialysis.
- Pediatric Patients < 15 years old with kidney transplantation in the monthly follow up.
- Recorded data for every patient. (Glomerular Filtration Rate, Creatinine level, urea level and calcium level).
Exclusion Criteria:
- Patients undergoing renal dialysis for reasons other than chronic kidney disease, such as acute renal failure secondary to accidents, trauma, snake poisoning.
- Patients undergoing peritoneal dialysis.
- Patients not physically able to participate in the examination.
- Chronic kidney disease patients at stage 2, 3 and 4.
研究計画
研究はどのように設計されていますか?
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
---|---|
Heamodialysis group
|
The data will be collected through a questionnaire that will be obtained through an interview between the investigator and the parent or the legal guardian
|
Kidney transplantation group
|
The data will be collected through a questionnaire that will be obtained through an interview between the investigator and the parent or the legal guardian
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Caries
時間枠:Five minutes
|
Clinical examination will be done and Caries index will be used ,Unit is the tooth to determine if there is caries or not
|
Five minutes
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Enamel hypoplasia
時間枠:Ten minutes
|
Clinical examination will be done on each patient to assess enamel hypoplasia and recorded by use of Modified Developmental Defect of Enamel (DDE) Index
|
Ten minutes
|
Oral candidiasis
時間枠:Five minutes
|
Clinical examination will be conducted to assess oral candidiasis and recorded by use of Lehner Oral Candidiasis Classification
|
Five minutes
|
Gingival overgrowth
時間枠:Five minutes
|
Clinical examination will be done to asess gingival overgrowth and recorded by use of Angelopoulos and Goaz index
|
Five minutes
|
協力者と研究者
スポンサー
研究記録日
主要日程の研究
研究開始 (予想される)
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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腎臓病、慢性の臨床試験
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Adelphi Values LLCBlueprint Medicines Corporation完了肥満細胞性白血病 (MCL) | 攻撃的な全身性肥満細胞症 (ASM) | SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD) | くすぶり全身性肥満細胞症 (SSM) | 無痛性全身性肥満細胞症 (ISM) ISM サブグループが完全に募集されましたアメリカ
Questionnaireの臨床試験
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Assistance Publique - Hôpitaux de Paris完了
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Centre Georges Francois Leclerc募集ステージ IV の非小細胞気管支肺癌であり、現在のフランスの推奨に従って第一選択治療の恩恵を受けるフランス
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Cambridge University Hospitals NHS Foundation TrustUniversity of Cambridgeわからない筋骨格疾患 | 筋骨格系損傷
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Centre Hospitalier Universitaire de Nīmes完了
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Assistance Publique - Hôpitaux de Parisまだ募集していません