시카고의 심혈관 및 비심혈관 위험의 역학
2016년 2월 17일 업데이트: National Heart, Lung, and Blood Institute (NHLBI)
4개의 시카고 인구 코호트에서 심혈관 및 암과 당뇨병을 포함한 기타 주요 만성 질환의 역학에 대한 포괄적인 연구 프로그램을 지속합니다.
4개의 코호트에는 산업 코호트의 Chicago Heart Association Detection Project, 1958-1959년에 처음 조사된 Peoples Gas Company 코호트, 1959-1962년에 처음 조사된 Peoples Gas Company 코호트 및 Western Electric Company 코호트가 포함됩니다.
연구 개요
상세 설명
배경:
지난 40년 동안 역학 연구는 심혈관 질환, 당뇨병 및 암과 같은 만성 질환의 병인 및 자연사에 대한 지식에 기본적인 기여를 했습니다. 역학 연구 결과는 생활 방식을 개선하고 필요한 경우 약물로 고혈압을 조절하기 위한 예방 및 통제 프로그램 개발을 위한 실질적인 토대를 제공했습니다. 이러한 발전과 라이프 스타일 및 위험 요인에 대한 영향은 아마도 1970년대와 1980년대에 걸쳐 관상 동맥 심장 질환, 뇌졸중, 모든 심혈관 질환 및 모든 원인으로 인한 사망률의 현저한 감소에 기여했을 것입니다.
4개의 역학 연구는 Albany 공무원 연구, Charleston 연구, Framingham Heart 연구, Tecumseh 연구 등을 포함한 초기 '1세대' 역학 연구의 주요 기여를 기반으로 합니다. 이러한 연구의 중요성은 주요 심혈관 및 비심혈관 만성 질환의 역학에서 핵심 '2세대' 문제를 설명할 수 있는 가능성에 있습니다.
디자인 내러티브:
산업 분야의 시카고 심장 협회 탐지 프로젝트: 1967년 가을부터 1973년 초까지 시카고 지역에 있는 85개 회사의 직원이 선별 검사를 받았습니다. 이들 회사의 총 노동력은 75,000명 이상이었습니다. 스크리닝 자원봉사자 비율은 55%였다. 모든 직원은 근무 유형이나 근무 교대 근무에 관계없이 참여하도록 권장되었습니다. 각 고용 사이트에서 흡연 습관, 이전 의료 진단, 고혈압, 심장병 및 당뇨병에 대한 현재 치료, 신장 및 체중, 연령, 성별, 인종, 심박수에 대한 데이터를 수집했습니다.
Peoples Gas Company: 두 코호트에 대한 모든 데이터는 정규 의사 직원이 회사 의료 부서의 모든 직원을 대상으로 정기 건강 검진 프로그램의 일부로 수집했습니다. 연령, 인종, 신장, 체중, 혈압, 혈청 콜레스테롤, 흡연 이력, 심박수, 휴식 ECG, 병력 및 가족력, 알코올 및 커피 및 차 소비, 교육, 병역, 직업, 신체 활동, 식이요법에 대한 데이터를 수집했습니다. , 포도당 및 혈청 요산 수치. 재검사는 50-59세 남성의 경우 매년, 40-49세 남성의 경우 2년마다, 25-39세 남성의 경우 4년마다 시행되었습니다.
Western Electric Company: 관상 동맥 심장 질환에 대한 이 종적 연구는 1957년 시카고에 있는 Western Electric Company의 Hawthorne Works에서 시작되었습니다. 남성 피험자는 기준선에서 관상 동맥 심장 질환이 없었습니다. 병력 및 신체 검사는 프레이밍햄 심장 연구(Framingham Heart Study)를 모델로 했습니다. 식이, 신체 활동, 심전도, 혈중 헤모글로빈 및 혈중 콜레스테롤 수치, 체지방, 혈압, 신장, 체중, 지단백 리파아제, 포도당 수치 및 흡연에 대한 데이터를 수집했습니다.
이 연구는 1992 회계연도에 갱신되었고 1998 회계연도에 다시 갱신되었습니다. 1998년 갱신에서는 4개 코호트의 데이터와 분석을 사용했습니다. 그것은 6가지 특정 목표에 초점을 맞췄습니다: 젊은 성인 여성과 남성(기준선에서 18~39세)의 관상동맥 심장 질환-심혈관 질환 위험에 장기적으로 영향을 미치는 요인; 관상 동맥 심장 질환-심혈관 질환 위험에 영향을 미치는 요인은 아프리카 계 미국인 여성과 남성에서 장기적으로 위험합니다. 조기 및 후기 추적(처음 15년 및 15년 이후) 동안 관상동맥 심장 질환-심혈관 질환 위험에 영향을 미치는 요인; 관상 동맥 심장 질환, 심혈관 질환, 비심혈관 질환 및 모든 원인으로 인한 장기 사망 위험에 대한 기준 저위험 상태의 영향; 다양한 식품군의 습관적 섭취와 혈청 콜레스테롤, 혈압, 체중의 10년 변화 및 관상 동맥 심장 질환, 심혈관 질환, 암 및 모든 원인으로 인한 30년 사망 위험과의 관계; 위험 요인의 차이는 성별, 인종, 연령 또는 위험 요인 상태에 따라 그룹 간에 영향을 미칩니다.
이 연구는 2005년 7월까지 연장되었으며 산업 코호트에서 Chicago Heart Association Detection Project의 데이터와 분석을 사용합니다. 이 연구는 세 가지 특정 목표에 초점을 맞추고 있습니다. 젊은 성인 여성(기준선에서 18-39세)의 관상 동맥 심장 질환 및 심혈관 질환 위험에 장기적으로 영향을 미치는 요인; 젊은 성인 및 중년 아프리카계 미국인 남성과 여성의 관상 동맥 심장 질환 및 심혈관 질환 위험에 장기적으로 영향을 미치는 요인; 관상 동맥 심장 질환, 심혈관 질환, 비심혈관 질환 및 아프리카계 미국인과 백인 여성을 포함한 젊은 성인 여성(18-39세)의 모든 원인으로 인한 장기 사망률에 대한 기준선 "저위험" 상태의 영향.
연구 유형
관찰
참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
100년 이하 (어린이, 성인, 고령자)
건강한 자원 봉사자를 받아들입니다
아니
연구 대상 성별
남성
설명
자격 기준 없음
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
- Philip Greenland, Northwestern University
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Daviglus ML, Liu K, Yan LL, Pirzada A, Manheim L, Manning W, Garside DB, Wang R, Dyer AR, Greenland P, Stamler J. Relation of body mass index in young adulthood and middle age to Medicare expenditures in older age. JAMA. 2004 Dec 8;292(22):2743-9. doi: 10.1001/jama.292.22.2743.
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- Daviglus ML, Liu K, Pirzada A, Yan LL, Garside DB, Greenland P, Manheim LM, Dyer AR, Wang R, Lubitz J, Manning WG, Fries JF, Stamler J. Cardiovascular risk profile earlier in life and Medicare costs in the last year of life. Arch Intern Med. 2005 May 9;165(9):1028-34. doi: 10.1001/archinte.165.9.1028.
- Liu K, Dyer AR, Vu TH, Pirzada A, Manheim LM, Manning WG, Ashraf MS, Garside DB, Daviglus ML. One-hour postload plasma glucose in middle age and Medicare expenditures in older age among nondiabetic men and women: the Chicago Heart Association Detection Project in Industry. Diabetes Care. 2005 May;28(5):1057-62. doi: 10.2337/diacare.28.5.1057.
- Yan LL, Daviglus ML, Liu K, Stamler J, Wang R, Pirzada A, Garside DB, Dyer AR, Van Horn L, Liao Y, Fries JF, Greenland P. Midlife body mass index and hospitalization and mortality in older age. JAMA. 2006 Jan 11;295(2):190-8. doi: 10.1001/jama.295.2.190.
- Greenland P, Knoll MD, Stamler J, Neaton JD, Dyer AR, Garside DB, Wilson PW. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA. 2003 Aug 20;290(7):891-7. doi: 10.1001/jama.290.7.891.
- Stamler J, Daviglus ML, Garside DB, Dyer AR, Greenland P, Neaton JD. Relationship of baseline serum cholesterol levels in 3 large cohorts of younger men to long-term coronary, cardiovascular, and all-cause mortality and to longevity. JAMA. 2000 Jul 19;284(3):311-8. doi: 10.1001/jama.284.3.311.
- LeGrady D, Dyer AR, Shekelle RB, Stamler J, Liu K, Paul O, Lepper M, Shryock AM. Coffee consumption and mortality in the Chicago Western Electric Company Study. Am J Epidemiol. 1987 Nov;126(5):803-12. doi: 10.1093/oxfordjournals.aje.a114717.
- Liao Y, Liu K, Dyer A, Schoenberger JA, Shekelle RB, Collette P, Stamler J. Sex differential in the relationship of electrocardiographic ST-T abnormalities to risk of coronary death: 11.5 year follow-up findings of the Chicago Heart Association Detection Project in Industry. Circulation. 1987 Feb;75(2):347-52. doi: 10.1161/01.cir.75.2.347.
- Liu K. Measurement error and its impact on partial correlation and multiple linear regression analyses. Am J Epidemiol. 1988 Apr;127(4):864-74. doi: 10.1093/oxfordjournals.aje.a114870.
- Clay CM, Dyer AR, Liu K, Stamler J, Shekelle RB, Berkson DM, Paul O, Schoenberger JA, Lepper M, Lindberg HA, et al. Education, smoking and non-cardiovascular mortality: findings in three Chicago epidemiological studies. Int J Epidemiol. 1988 Jun;17(2):341-7. doi: 10.1093/ije/17.2.341.
- Levine W, Dyer AR, Shekelle RB, Schoenberger JA, Stamler J. Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry. J Clin Epidemiol. 1989;42(3):257-67. doi: 10.1016/0895-4356(89)90061-9.
- Levine W, Dyer AR, Shekelle RB, Schoenberger JA, Stamler J. Post-load plasma glucose and cancer mortality in middle-aged men and women. 12-year follow-up findings of the Chicago Heart Association Detection Project in Industry. Am J Epidemiol. 1990 Feb;131(2):254-62. doi: 10.1093/oxfordjournals.aje.a115495.
- Dyer AR, Stamler J, Shekelle RB. Serum cholesterol and mortality from coronary heart disease in young, middle-aged, and older men and women from three Chicago epidemiologic studies. Ann Epidemiol. 1992 Jan-Mar;2(1-2):51-7. doi: 10.1016/1047-2797(92)90037-q.
- Vaccaro O, Ruth KJ, Stamler J. Relationship of postload plasma glucose to mortality with 19-yr follow-up. Comparison of one versus two plasma glucose measurements in the Chicago Peoples Gas Company Study. Diabetes Care. 1992 Oct;15(10):1328-34. doi: 10.2337/diacare.15.10.1328.
- Shekelle RB, Tangney CC, Rossof AH, Stamler J. Serum cholesterol, beta-carotene, and risk of lung cancer. Epidemiology. 1992 Jul;3(4):282-7. doi: 10.1097/00001648-199207000-00003.
- Goff DC Jr, Shekelle RB, Katan MB, Gotto AM Jr, Stamler J. Does body fatness modify the association between dietary cholesterol and risk of coronary death? Results from the Chicago Western Electric Study. Arterioscler Thromb. 1992 Jul;12(7):755-61. doi: 10.1161/01.atv.12.7.755.
- Stamler J. Diet and coronary heart disease. Biometrics. 1982 Mar;38 Suppl:95-118.
- Liu K, Stamler J, Stamler R, Cooper R, Shekelle RB, Schoenberger JA, Berkson DM, Lindberg HA, Marquardt J, Stevens E, Tokich T. Methodological problems in characterizing an individual's plasma glucose level. J Chronic Dis. 1982;35(6):475-85. doi: 10.1016/0021-9681(82)90062-5.
- Circulating cholesterol level and risk of death from cancer in men aged 40 to 69 years. Experience of an international collaborative group. JAMA. 1982 Dec 3;248(21):2853-9. doi: 10.1001/jama.1982.03330210035031.
- Liu K, Cedres LB, Stamler J, Dyer A, Stamler R, Nanas S, Berkson DM, Paul O, Lepper M, Lindberg HA, Marquardt J, Stevens E, Schoenberger JA, Shekelle RB, Collette P, Shekelle S, Garside D. Relationship of education to major risk factors and death from coronary heart disease, cardiovascular diseases and all causes, Findings of three Chicago epidemiologic studies. Circulation. 1982 Dec;66(6):1308-14. doi: 10.1161/01.cir.66.6.1308. No abstract available.
- Dyer AR, Stamler J, Shekelle RB, Schoenberger JA, Stamler R, Shekelle S, Berkson DM, Paul O, Lepper MH, Lindberg HA. Relative weight and blood pressure in four Chicago epidemiologic studies. J Chronic Dis. 1982;35(12):897-908. doi: 10.1016/0021-9681(82)90121-7.
- Larbi EB, Cooper RS, Stamler J. Alcohol and hypertension. Arch Intern Med. 1983 Jan;143(1):28-9. No abstract available.
- Stamler J. Nutrition-related risk factors for the atherosclerotic diseases--present status. Prog Biochem Pharmacol. 1983;19:245-308. No abstract available.
- Trevisan M, Ostrow D, Cooper R, Liu K, Sparks S, Okonek A, Stevens E, Marquardt J, Stamler J. Abnormal red blood cell ion transport and hypertension. The People's Gas Company study. Hypertension. 1983 May-Jun;5(3):363-7. doi: 10.1161/01.hyp.5.3.363.
- Stamler J, Stamler R, Liu K: High Blood Pressure: Role in Coronay Heart Disease, and Implications for Prevention and Control. In: Connor WE, Bristow DJ (Eds), Coronary Heart Disease - Prevention, Complications, and Treatment, Lippincott, Philadelphia, Pa, p 85-109, 1985
- Stamler J, Farinaro E, Riccardi G, Stamler R, Mancini M: Does asymptomatic Hyperglycemia Always Have to be Treated? (Italian), J Ital Diabetol, 3:1-7, 1983
- Trevisan M, Tsong Y, Stamler J, Tokich T, Mojonnier L, Hall Y, Cooper R, Moss D. Nervous tension and serum cholesterol: findings from the Chicago Coronary Prevention Evaluation Program. J Human Stress. 1983 Mar;9(1):12-6. doi: 10.1080/0097840X.1983.9935020.
- Stamler J. The prevention and control of epidemic coronary heart disease: scientific foundations and strategic approaches. Int J Cardiol. 1983 Sep;4(2):207-15. doi: 10.1016/0167-5273(83)90138-9. No abstract available.
- Kaplan NM, Stamler J (Eds): Prevention of Coronary Heart Disease--Practical Management of the Risk Factors, WB Saunders, Philadelphia, 1983
- Stamler J, Liu K: The Benefits of Prevention. In: Kaplan NM, Stamler J (Eds), Prevention of Coronary Heart Disease--Practical Management of the Risk Factors, WB Saunders, Philadelphia, pp 188-207, 1983
- Stamler R, Stamler J: 'Mild' Hypertension: Risks and Strategy. Parts I and II. Primary Cardiol, 9(10):150-166, Oct, and 9(11):12-25, Nov, 1983
- Stamler J, Stamler R, Liu K: High Blood Pressure: Role in Coronary Heart Disease, and Implications for Prevention and Control. Position Paper Prepared at the Request of the Non-Communicable Disease Division, and the Cardiovascular Section, World Health Organization, Geneva, Switzerland, WHO/CVD/83.5, 8th August, 1983
- Stamler J: Does Cholesterol Change Alter Coronary Artery Disease Risk? Epidemiological Evidence. Proceedings of a Symposium on the Decline in Coronary Heart Disease Mortality--the Role of Cholesterol Change. Science and Medicine, New York, pp 27-45, 1983
- Coffee and cholesterol. N Engl J Med. 1983 Nov 17;309(20):1248-50. doi: 10.1056/NEJM198311173092012. No abstract available.
- Ueshima H, Cooper R, Stamler J, Yu C, Tatara K, Asakura S. Age specific mortality trends in the U.S.A. from 1960 to 1980: divergent age-sex-color patterns. J Chronic Dis. 1984;37(6):425-39. doi: 10.1016/0021-9681(84)90026-2.
- Kannel WB, Doyle JT, Ostfeld AM, Jenkins CD, Kuller L, Podell RN, Stamler J. Optimal resources for primary prevention of atherosclerotic diseases. Atherosclerosis Study Group. Circulation. 1984 Jul;70(1):155A-205A.
- Larbi EB, Stamler J, Dyer A, Cooper R, Paul O, Shekelle RB, Lepper M. The population attributable risk of hypertension from heavy alcohol consumption. Public Health Rep. 1984 May-Jun;99(3):316-9.
- Cooper R, Liu K, Stamler J, Schoenberger JA, Shekelle RB, Collette P, Shekelle S. Prevalence of diabetes/hyperglycemia and associated cardiovascular risk factors in blacks and whites: Chicago Heart Association Detection Project in Industry. Am Heart J. 1984 Sep;108(3 Pt 2):827-33. doi: 10.1016/0002-8703(84)90678-1.
- Trevisan M, Ostrow D, Cooper RS, Sempos C, Stamler J. Sex and race differences in sodium-lithium countertransport and red cell sodium concentration. Am J Epidemiol. 1984 Oct;120(4):537-41. doi: 10.1093/oxfordjournals.aje.a113914.
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- Cooper R, Trevisan M, Ostrow D, Sempos C, Stamler J. Blood pressure and sodium-lithium countertransport: findings in population-based surveys. J Hypertens. 1984 Oct;2(5):467-71. doi: 10.1097/00004872-198410000-00004.
- Stamler J: The Central and Essential Role of Nutrition in the Primary and Secondary Prevention of Coronary Heart Disease and Hypertension. In: Lovenberg W, Yamori Y, (Eds), Nutritional Prevention of Cardiovascular Disease, Academic Press, New York, NY, pp 383-405, 1984
- Stamler J, Stamler R, Liu K: High Blood Pressure. In: Connor WE, Bristow D (Eds), Coronary Heart Disease--Prevention, Complications, and Treatment, JB Lippincott, Philadelphia, Pa, pp 85-109, 1985
- Giumetti D, Liu K, Stamler R, Schoenberger JA, Shekelle RB, Stamler J. Need to prevent and control high-normal and high blood pressure, particularly so-called "mild" hypertension: epidemiological and clinical data. Prev Med. 1985 Jul;14(4):396-412. doi: 10.1016/0091-7435(85)90002-7.
- Stamler R. Influence of treatment of "mild" hypertension on coronary heart disease. Acta Med Scand Suppl. 1985;701:89-99. doi: 10.1111/j.0954-6820.1985.tb08894.x.
- Pan WH, Cedres LB, Liu K, Dyer A, Schoenberger JA, Shekelle RB, Stamler R, Smith D, Collette P, Stamler J. Relationship of clinical diabetes and asymptomatic hyperglycemia to risk of coronary heart disease mortality in men and women. Am J Epidemiol. 1986 Mar;123(3):504-16. doi: 10.1093/oxfordjournals.aje.a114266.
- Dyer AR. A method for combining results from several prospective epidemiologic studies. Stat Med. 1986 Jul-Aug;5(4):303-17. doi: 10.1002/sim.4780050403.
- Fish consumption and mortality from coronary heart disease. N Engl J Med. 1985 Sep 26;313(13):820-4. doi: 10.1056/NEJM198509263131311. No abstract available.
- Liao YL, Emidy LA, Dyer A, Hewitt JS, Shekelle RB, Paul O, Prineas R, Stamler J. Characteristics and prognosis of incomplete right bundle branch block: an epidemiologic study. J Am Coll Cardiol. 1986 Mar;7(3):492-9. doi: 10.1016/s0735-1097(86)80458-2.
- Nanas S, Pan WH, Stamler J, Liu K, Dyer A, Stamler R, Schoenberger JA, Shekelle RB. The role of relative weight in the positive association between age and serum cholesterol in men and women. J Chronic Dis. 1987;40(9):887-92. doi: 10.1016/0021-9681(87)90189-5.
- Pan WH, Nanas S, Dyer A, Liu K, McDonald A, Schoenberger JA, Shekelle RB, Stamler R, Stamler J. The role of weight in the positive association between age and blood pressure. Am J Epidemiol. 1986 Oct;124(4):612-23. doi: 10.1093/oxfordjournals.aje.a114434.
- Persky V, Pan WH, Stamler J, Dyer A, Levy P. Time trends in the US racial difference in hypertension. Am J Epidemiol. 1986 Nov;124(5):724-37. doi: 10.1093/oxfordjournals.aje.a114448.
- Stamler J, Giumetti D, Liu K, Stamler R, Dyer A: The Risks of Hypertension. Proceedings of the Symposium on Control of Arterial Hypertension in the Prevention of Cardiovascular Disease, Hohenreid, Federal Republic of Germany, 1986.
- Liu K. Statistical issues related to the design of dietary survey methodology for NHANES III. Vital Health Stat 4. 1992 Mar;(27):3-14; discussion 15-23. No abstract available.
- Crews DE, Stamler J, Dyer A. Conditions other than underlying cause of death listed on death certificates provide additional useful information for epidemiologic research. Epidemiology. 1991 Jul;2(4):271-5. doi: 10.1097/00001648-199107000-00006.
- Almada SJ, Zonderman AB, Shekelle RB, Dyer AR, Daviglus ML, Costa PT Jr, Stamler J. Neuroticism and cynicism and risk of death in middle-aged men: the Western Electric Study. Psychosom Med. 1991 Mar-Apr;53(2):165-75. doi: 10.1097/00006842-199103000-00006.
- Persky V, Ostrow D, Langenberg P, Ruby E, Bresolin L, Stamler J. Hypertension and sodium transport in 390 healthy adults in Chicago. J Hypertens. 1990 Feb;8(2):121-8. doi: 10.1097/00004872-199002000-00005.
- Orencia AJ, Daviglus ML, Dyer AR, Shekelle RB, Stamler J. Fish consumption and stroke in men. 30-year findings of the Chicago Western Electric Study. Stroke. 1996 Feb;27(2):204-9. doi: 10.1161/01.str.27.2.204.
- Gann PH, Daviglus ML, Dyer AR, Stamler J. Heart rate and prostate cancer mortality: results of a prospective analysis. Cancer Epidemiol Biomarkers Prev. 1995 Sep;4(6):611-6.
- Pandey DK, Shekelle R, Selwyn BJ, Tangney C, Stamler J. Dietary vitamin C and beta-carotene and risk of death in middle-aged men. The Western Electric Study. Am J Epidemiol. 1995 Dec 15;142(12):1269-78. doi: 10.1093/oxfordjournals.aje.a117594.
- Xie X, Liu K, Stamler J, Stamler R. Ethnic differences in electrocardiographic left ventricular hypertrophy in young and middle-aged employed American men. Am J Cardiol. 1994 Mar 15;73(8):564-7. doi: 10.1016/0002-9149(94)90334-4.
- Stamler J, Dyer AR, Shekelle RB, Neaton J, Stamler R. Relationship of baseline major risk factors to coronary and all-cause mortality, and to longevity: findings from long-term follow-up of Chicago cohorts. Cardiology. 1993;82(2-3):191-222. doi: 10.1159/000175868.
- Birmingham B, Dyer AR, Shekelle RB, Stamler J. Subscapular and triceps skinfold thicknesses, body mass index and cardiovascular risk factors in a cohort of middle-aged employed men. J Clin Epidemiol. 1993 Mar;46(3):289-302. doi: 10.1016/0895-4356(93)90077-e.
- Goff DC Jr, Shekelle RB, Moye LA, Katan MB, Gotto AM Jr, Stamler J. Does body fatness modify the effect of dietary cholesterol on serum cholesterol? Results from the Chicago Western Electric Study. Am J Epidemiol. 1993 Jan 15;137(2):171-7. doi: 10.1093/oxfordjournals.aje.a116657.
- Stamler J. The mass treatment of hypertensive disease: defining the problem. Ann N Y Acad Sci. 1978 Mar 30;304:333-62. doi: 10.1111/j.1749-6632.1978.tb25611.x. No abstract available.
- Stamler J. Hypertension, blood lipids, and cigarette smoking as co-risk factors for coronary heart disease: discussion. Ann N Y Acad Sci. 1978 Mar 30;304:140-6. doi: 10.1111/j.1749-6632.1978.tb25586.x. No abstract available.
- Stamler J. George Lyman Duff Memorial Lecture. Lifestyles, major risk factors, proof and public policy. Circulation. 1978 Jul;58(1):3-19. doi: 10.1161/01.cir.58.1.3.
- Stamler R, Stamler J. Where do we go in hypertension screening? Urban Health. 1978 Jun;7(5):8-9, 16. No abstract available.
- Stamler J: Improving Life Styles to Control the Coronary Epidemic. Proceedings of the International Conference on Nutrition, Dietetics and Sport. Edizioni Minerva Medica, Torino, p 5, 1978
- Stamler J: Clinical Problems in Hypertension #2. A Patient with Mild Hypertension. A Taped Presentation. Health Learning Systems, Inc, Bloomfield NJ, 1978
- Stamler J: Epidemiology and Treatment of Hypertension. In: Carlson RJ, Cunningham R, (Eds), Future Directions in Health Care: A New Public Policy, Ballinger Publishing Co, Cambridge, MA, p 95, 1978
- Stamler J: Population Studies. In: Levy RI, Rifkind BM, Dennis BH, Ernst ND, (Eds), Nutrition, Lipids, and Coronary Heart Disease--A Global View, Raven Press, New York, p 25, 1979
- Persky VW, Dyer AR, Idris-Soven E, Stamler J, Shekelle RB, Schoenberger JA, Berkson DM, Lindberg HA. Uric acid: a risk factor for coronary heart disease? Circulation. 1979 May;59(5):969-77. doi: 10.1161/01.cir.59.5.969.
- Persky V, Dyer A, Stamler J, Shekelle RB, Schoenberger J, Wannamaker J, Upton M. The relationship between post-load plasma glucose and blood pressure at different resting heart rates. J Chronic Dis. 1979;32(3):263-8. doi: 10.1016/0021-9681(79)90072-9. No abstract available.
- Stamler R, Stamler J, Dyer A, Cooper R, Collette P, Berkson DM, Lindberg HA, Stevens E, Schoenberger JA, Shekelle RB, Shekelle S, Paul O, Lepper M, Garside D, Tokich T, Hoeksema R. Asymptomatic hyperglycemia and cardiovascular diseases in three Chicago epidemiologic studies. Diabetes Care. 1979 Mar-Apr;2(2):142-3. doi: 10.2337/diacare.2.2.142. No abstract available.
- Persky VW, Dyer AR, Stamler J, Shekelle RB, Schoenberger JA. Racial patterns of heart rate in an employed adult population. Am J Epidemiol. 1979 Sep;110(3):274-80. doi: 10.1093/oxfordjournals.aje.a112812.
- Stamler R, Stamler J, Lindberg HA, Marquardt J, Berkson DM, Paul O, Lepper M, Dyer A, Stevens E. Asymptomatic hyperglycemia and coronary heart disease in middle-aged men in two employed populations in Chicago. J Chronic Dis. 1979;32(11-12):805-15. doi: 10.1016/0021-9681(79)90060-2. No abstract available.
- Stamler R, Stamler J, Schoenberger JA, Shekelle RB, Collette P, Shekelle S, Dyer A, Garside D, Wannamaker J. Relationship of glucose tolerance to prevalence of ECG abnormalities and to 5-year mortality from cardiovascular disease: findings of the Chicago Heart Association Detection Project in Industry. J Chronic Dis. 1979;32(11-12):817-28. doi: 10.1016/0021-9681(79)90061-4. No abstract available.
- Joint discussion: the International Collaborative Group. J Chronic Dis. 1979;32(11-12):829-37. No abstract available.
- Stamler J. Research related to risk factors. Circulation. 1979 Dec;60(7):1575-87. doi: 10.1161/01.cir.60.7.1575. No abstract available.
- Stamler J: Overweight, Hypertension, Hypercholesterolemia and Coronary Heart Disease. In: Mancini M, (Ed), Medical Complications of Obesity, Proceedings of an International Conference, Naples, Italy, June 1978, Academic Press, London, 191-216, 1979
- Stamler J: Should Hyperglycemia Always be Treated? In: Mancini M, (Ed), Diet and Drugs in the Treatment of Maturity-Onset Diabetes, Proceedings of a Symposium, Naples, Italy, 28 June 1979
- Asymptomatic hyperglycemia and coronary heart disease. A series of papers by the International Collaborative Group, based on studies in fifteen populations. Introduction. J Chronic Dis. 1979;32(11-12):683-91. doi: 10.1016/0021-9681(79)90047-x. No abstract available.
- Stamler J: Hypertension: Aspects of Risk. In: Hunt JC, Cooper T, Frohlich ED, Gifford RW Jr, Kaplan NM, Laragh JH, Maxwell MH, Strong CG (Eds), Hypertension Update: Mechanisms, Epidemiology, Evaluation, Management, Health Learning Systems, Inc, Bloomfield, NJ, pp 23-37, 1979
- Stamler J. Public health aspects of optimal serum lipid-lipoprotein levels. Prev Med. 1979 Nov;8(6):733-59. doi: 10.1016/0091-7435(79)90357-8. No abstract available.
- Stamler J: Can An Effective Fat-Modified Diet Be Safely Recommended After Weaning for Infants and Children in General: D. General Discussion. In: Lauer RM, Shekelle RB (Eds), Childhood Prevention of Atherosclerosis and Hypertension, Raven Press, New York, pp 407-410, 1980
- Dyer AR, Persky V, Stamler J, Paul O, Shekelle RB, Berkson DM, Lepper M, Schoenberger JA, Lindberg HA. Heart rate as a prognostic factor for coronary heart disease and mortality: findings in three Chicago epidemiologic studies. Am J Epidemiol. 1980 Dec;112(6):736-49. doi: 10.1093/oxfordjournals.aje.a113046.
- Stamler J: Asymptomatic Hyperglycemia and Risk of Coronary Heart Disease in Middle-Aged Men: American and International Experience. Proceedings, Diabetes and Atherosclerosis Workshop, Dallas, Texas, March 27-29, 1980
- Stamler J: Data Base on the Major Cardiovascular Diseases in the United States. In: Hegyeli R (Ed), Measurement and Control of Cardiovascular Risk Factors, Atherosclerosis Reviews, Vol. 7, Raven Press, New York, pp 49-96, 1980
- Stamler J. The established relationship among diet, serum cholesterol and coronary heart disease. Acta Med Scand. 1980;207(6):433-46. doi: 10.1111/j.0954-6820.1980.tb09752.x. No abstract available.
- Stamler J. Primary prevention of coronary heart disease: the last 20 years. Am J Cardiol. 1981 Mar;47(3):722-35. No abstract available.
- Berkson DM, Stamler J. Epidemiology of the killer chronic diseases. Curr Concepts Nutr. 1981;10:17-55. No abstract available.
- Persky V, Dyer AR, Leonas J, Stamler J, Berkson DM, Lindberg HA, Paul O, Shekelle RB, Lepper MH, Schoenberger JA. Heart rate: a risk factor for cancer? Am J Epidemiol. 1981 Oct;114(4):477-87. doi: 10.1093/oxfordjournals.aje.a113213.
- Dyer AR, Stamler J, Paul O, Shekelle RB, Schoenberger JA, Berkson DM, Lepper M, Collette P, Shekelle S, Lindberg HA. Serum cholesterol and risk of death from cancer and other causes in three Chicago epidemiological studies. J Chronic Dis. 1981;34(6):249-60. doi: 10.1016/0021-9681(81)90030-8. No abstract available.
- Stamler J: Improved Life Styles: Their Potential for the Primary Prevention of Atherosclerosis and Hypertension in Childhood. In: Childhood Prevention of Atherosclerosis and Hypertension, Raven Press, New York, 1980
- Stamler J, Stamler R: Maturity-Onset Diabetes and Asymptomatic Hyperglycemia. Diabetes and Atherosclerosis Workshop, Sponsored by the Juvenile Diabetes Foundation and the National Heart, Lung, and Blood Institute, Dallas TX, March 27-29, 1980, Juvenile Diabetes Foundation, New York, pp 17-43, 1981
- Cedres BL, Liu K, Stamler J, Dyer AR, Stamler R, Berkson DM, Paul O, Lepper M, Lindberg HA, Marquardt J, Stevens E, Schoenberger JA, Shekelle RB, Collette P, Garside D. Independent contribution of electrocardiographic abnormalities to risk of death from coronary heart disease, cardiovascular diseases and all causes. Findings of three Chicago epidemiologic studies. Circulation. 1982 Jan;65(1):146-53. doi: 10.1161/01.cir.65.1.146. No abstract available.
- Shekelle RB, Paul O, Shryock AM, Stamler J: Dietary Lipids, Serum Cholesterol Concentration, and Risk of Death from Coronary Heart Disease. In: Noseda G, Fragiacomo C, Fumagalli R, Paoletti R (Eds). Lipoproteins and Coronary Atherosclerosis, Elsevier Biomedical Press BV, Amsterdam, pp 87-94, 1982
- Dyer AR, Stamler J, Shekelle RB, Schoenberger JA, Stamler R, Shekelle S, Berkson DM, Paul O, Lepper MH, Lindberg HA. Pulse pressure-I. Level and associated factors in four Chicago epidemiologic studies. J Chronic Dis. 1982;35(4):259-73. doi: 10.1016/0021-9681(82)90082-0.
- Dyer AR, Stamler J, Shekelle RB, Schoenberger JA, Stamler R, Shekelle S, Berkson DM, Paul O, Lepper MH, Lindberg HA. Pulse pressure-II. Factors associated with follow-up values in three Chicago epidemiologic studies. J Chronic Dis. 1982;35(4):275-82. doi: 10.1016/0021-9681(82)90083-2.
- Dyer AR, Stamler J, Shekelle RB, Schoenberger JA, Stamler R, Shekelle S, Collette P, Berkson DM, Paul O, Lepper MH, Lindberg HA. Pulse pressure-III. Prognostic significance in four Chicago epidemiologic studies. J Chronic Dis. 1982;35(4):283-94. doi: 10.1016/0021-9681(82)90084-4.
- Shekelle RB, Stamler J, Paul O, Shryock AM, Liu S, Lepper M. Dietary lipids and serum cholesterol level: change in diet confounds the cross-sectional association. Am J Epidemiol. 1982 Apr;115(4):506-14. doi: 10.1093/oxfordjournals.aje.a113332.
- Orencia AJ, Daviglus ML, Dyer AR, Walsh M, Greenland P, Stamler J. One-hour postload plasma glucose and risks of fatal coronary heart disease and stroke among nondiabetic men and women: the Chicago Heart Association Detection Project in Industry (CHA) Study. J Clin Epidemiol. 1997 Dec;50(12):1369-76. doi: 10.1016/s0895-4356(97)00201-1.
- Daviglus ML, Orencia AJ, Dyer AR, Liu K, Morris DK, Persky V, Chavez N, Goldberg J, Drum M, Shekelle RB, Stamler J. Dietary vitamin C, beta-carotene and 30-year risk of stroke: results from the Western Electric Study. Neuroepidemiology. 1997;16(2):69-77. doi: 10.1159/000109673.
- Daviglus ML, Dyer AR, Persky V, Chavez N, Drum M, Goldberg J, Liu K, Morris DK, Shekelle RB, Stamler J. Dietary beta-carotene, vitamin C, and risk of prostate cancer: results from the Western Electric Study. Epidemiology. 1996 Sep;7(5):472-7.
- Spataro JA, Dyer AR, Stamler J, Shekelle RB, Greenlund K, Garside D. Measures of adiposity and coronary heart disease mortality in the Chicago Western Electric Company Study. J Clin Epidemiol. 1996 Aug;49(8):849-57. doi: 10.1016/0895-4356(96)00067-4.
- Lowe LP, Liu K, Greenland P, Metzger BE, Dyer AR, Stamler J. Diabetes, asymptomatic hyperglycemia, and 22-year mortality in black and white men. The Chicago Heart Association Detection Project in Industry Study. Diabetes Care. 1997 Feb;20(2):163-9. doi: 10.2337/diacare.20.2.163.
- Greenland P, Daviglus ML, Dyer AR, Liu K, Huang CF, Goldberger JJ, Stamler J. Resting heart rate is a risk factor for cardiovascular and noncardiovascular mortality: the Chicago Heart Association Detection Project in Industry. Am J Epidemiol. 1999 May 1;149(9):853-62. doi: 10.1093/oxfordjournals.aje.a009901.
- Daviglus ML, Liao Y, Greenland P, Dyer AR, Liu K, Xie X, Huang CF, Prineas RJ, Stamler J. Association of nonspecific minor ST-T abnormalities with cardiovascular mortality: the Chicago Western Electric Study. JAMA. 1999 Feb 10;281(6):530-6. doi: 10.1001/jama.281.6.530.
- Lowe LP, Greenland P, Ruth KJ, Dyer AR, Stamler R, Stamler J. Impact of major cardiovascular disease risk factors, particularly in combination, on 22-year mortality in women and men. Arch Intern Med. 1998 Oct 12;158(18):2007-14. doi: 10.1001/archinte.158.18.2007.
- Daviglus ML, Liu K, Greenland P, Dyer AR, Garside DB, Manheim L, Lowe LP, Rodin M, Lubitz J, Stamler J. Benefit of a favorable cardiovascular risk-factor profile in middle age with respect to Medicare costs. N Engl J Med. 1998 Oct 15;339(16):1122-9. doi: 10.1056/NEJM199810153391606.
- Dyer AR, Stamler J, Greenland P. Associations of weight change and weight variability with cardiovascular and all-cause mortality in the Chicago Western Electric Company Study. Am J Epidemiol. 2000 Aug 15;152(4):324-33. doi: 10.1093/aje/152.4.324.
- Navas-Nacher EL, Colangelo L, Beam C, Greenland P. Risk factors for coronary heart disease in men 18 to 39 years of age. Ann Intern Med. 2001 Mar 20;134(6):433-9. doi: 10.7326/0003-4819-134-6-200103200-00007. Erratum In: Ann Intern Med 2001 Jul 3;135(1):71.
- Blanco-Cedres L, Daviglus ML, Garside DB, Liu K, Pirzada A, Stamler J, Greenland P. Relation of cigarette smoking to 25-year mortality in middle-aged men with low baseline serum cholesterol: the Chicago Heart Association Detection Project in Industry. Am J Epidemiol. 2002 Feb 15;155(4):354-60. doi: 10.1093/aje/155.4.354.
- Gapstur SM, Gann PH, Colangelo LA, Barron-Simpson R, Kopp P, Dyer A, Liu K. Postload plasma glucose concentration and 27-year prostate cancer mortality (United States). Cancer Causes Control. 2001 Oct;12(8):763-72. doi: 10.1023/a:1011279907108.
- Miura K, Daviglus ML, Dyer AR, Liu K, Garside DB, Stamler J, Greenland P. Relationship of blood pressure to 25-year mortality due to coronary heart disease, cardiovascular diseases, and all causes in young adult men: the Chicago Heart Association Detection Project in Industry. Arch Intern Med. 2001 Jun 25;161(12):1501-8. doi: 10.1001/archinte.161.12.1501.
- Stamler J, Liu K, Ruth KJ, Pryer J, Greenland P. Eight-year blood pressure change in middle-aged men: relationship to multiple nutrients. Hypertension. 2002 May;39(5):1000-6. doi: 10.1161/01.hyp.0000016178.80811.d9.
- Miura K, Dyer AR, Greenland P, Daviglus ML, Hill M, Liu K, Garside DB, Stamler J; Chicago Heart Association. Pulse pressure compared with other blood pressure indexes in the prediction of 25-year cardiovascular and all-cause mortality rates: The Chicago Heart Association Detection Project in Industry Study. Hypertension. 2001 Aug;38(2):232-7. doi: 10.1161/01.hyp.38.2.232.
- Colangelo LA, Gapstur SM, Gann PH, Dyer AR, Liu K. Colorectal cancer mortality and factors related to the insulin resistance syndrome. Cancer Epidemiol Biomarkers Prev. 2002 Apr;11(4):385-91.
- Rodin MB, Daviglus ML, Wong GC, Liu K, Garside DB, Greenland P, Stamler J. Middle age cardiovascular risk factors and abdominal aortic aneurysm in older age. Hypertension. 2003 Jul;42(1):61-8. doi: 10.1161/01.HYP.0000078829.02288.98. Epub 2003 Jun 9.
- Greenland P, Xie X, Liu K, Colangelo L, Liao Y, Daviglus ML, Agulnek AN, Stamler J. Impact of minor electrocardiographic ST-segment and/or T-wave abnormalities on cardiovascular mortality during long-term follow-up. Am J Cardiol. 2003 May 1;91(9):1068-74. doi: 10.1016/s0002-9149(03)00150-4.
- Colangelo LA, Gapstur SM, Gann PH, Dyer AR. Cigarette smoking and colorectal carcinoma mortality in a cohort with long-term follow-up. Cancer. 2004 Jan 15;100(2):288-93. doi: 10.1002/cncr.11923.
- Pirzada A, Yan LL, Garside DB, Schiffer L, Dyer AR, Daviglus ML. Response rates to a questionnaire 26 years after baseline examination with minimal interim participant contact and baseline differences between respondents and nonrespondents. Am J Epidemiol. 2004 Jan 1;159(1):94-101. doi: 10.1093/aje/kwh012.
- Dyer AR, Stamler J, Garside DB, Greenland P. Long-term consequences of body mass index for cardiovascular mortality: the Chicago Heart Association Detection Project in Industry study. Ann Epidemiol. 2004 Feb;14(2):101-8. doi: 10.1016/S1047-2797(03)00121-2.
- Daviglus ML, Stamler J, Pirzada A, Yan LL, Garside DB, Liu K, Wang R, Dyer AR, Lloyd-Jones DM, Greenland P. Favorable cardiovascular risk profile in young women and long-term risk of cardiovascular and all-cause mortality. JAMA. 2004 Oct 6;292(13):1588-92. doi: 10.1001/jama.292.13.1588.
- Daviglus ML, Pirzada A, Liu K, Yan LL, Garside DB, Dyer AR, Hoff JA, Kondos GT, Greenland P, Stamler J. Comparison of low risk and higher risk profiles in middle age to frequency and quantity of coronary artery calcium years later. Am J Cardiol. 2004 Aug 1;94(3):367-9. doi: 10.1016/j.amjcard.2004.04.038.
- Miura K, Greenland P, Stamler J, Liu K, Daviglus ML, Nakagawa H. Relation of vegetable, fruit, and meat intake to 7-year blood pressure change in middle-aged men: the Chicago Western Electric Study. Am J Epidemiol. 2004 Mar 15;159(6):572-80. doi: 10.1093/aje/kwh085.
- Daviglus ML, Liu K, Pirzada A, Yan LL, Garside DB, Wang R, Van Horn L, Manning WG, Manheim LM, Dyer AR, Greenland P, Stamler J. Relationship of fruit and vegetable consumption in middle-aged men to medicare expenditures in older age: the Chicago Western Electric Study. J Am Diet Assoc. 2005 Nov;105(11):1735-44. doi: 10.1016/j.jada.2005.08.008.
- Shekelle RB, Rossof AH, Stamler J. Dietary cholesterol and incidence of lung cancer: the Western Electric Study. Am J Epidemiol. 1991 Sep 1;134(5):480-4; discussion 543-4. doi: 10.1093/oxfordjournals.aje.a116119.
- Daviglus ML, Stamler J, Orencia AJ, Dyer AR, Liu K, Greenland P, Walsh MK, Morris D, Shekelle RB. Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med. 1997 Apr 10;336(15):1046-53. doi: 10.1056/NEJM199704103361502.
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연구 주요 날짜
연구 시작
1977년 9월 1일
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2006년 7월 1일
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2006년 7월 1일
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2000년 5월 25일
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2000년 5월 25일
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2000년 5월 26일
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2016년 2월 18일
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심장 질환에 대한 임상 시험
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Medical University of BialystokInstitute of Cardiology, Warsaw, Poland; Medical University of Lodz; Poznan University of... 그리고 다른 협력자들아직 모집하지 않음심부전, 수축기 | 박출률이 감소된 심부전 | 심부전 New York Heart Association Class IV | 심부전 New York Heart Association Class III폴란드
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Novartis Pharmaceuticals완전한핵심 연구의 12개월 치료 기간을 성공적으로 완료한 환자(de Novo Heart Recipients)는 EC-MPS 치료에 관심이 있었습니다.
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University of WashingtonAmerican Heart Association완전한심부전，울혈 | 미토콘드리아 변경 | 심부전 New York Heart Association Class IV미국
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University of Pennsylvania완전한Intrntl Classification of Diseases, 9th Revision, (ICD-9-CM) 410의 주진단 또는 이차진단 코드가 있는 환자(5번째 숫자가 2인 경우 제외)미국