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Long-Term Effects Of An Early Individualised Retraining Programme On Walking Ability In Patients Following Hemiplegic Stroke (letswalk)

24. juli 2013 oppdatert av: Centre Hospitalier Universitaire Dijon
This project aims to study the effects early individualised retraining programme on walking ability in patients following hemiplegic stroke.

Studieoversikt

Status

Avsluttet

Forhold

Studietype

Observasjonsmessig

Registrering (Faktiske)

14

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år til 85 år (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Prøvetakingsmetode

Sannsynlighetsprøve

Studiepopulasjon

patients hospitalized in the Physical Medicine and Rehabilitation (PMR) units of Dijon and Besançon CHU, and the Functional Rehabilitation Centres of Divio (Dijon) and Bregille (Besançon)

Beskrivelse

Inclusion Criteria:

  • Patients benefiting from classical rehabilitation following cardiovascular accident (cerebral infarction or spontaneous intracerebral hematoma) according to current recommendations (conference de consensus sur l'orientation des patients atteints d'AVC des societes Françaises de Medecine Physique et Readaptation (MPR), d'Urgence Neuro-Vasculaire et de Geriatrie et Gerontologie), hospitalized in the Physical Medicine and Rehabilitation (PMR) units of Dijon and Besançon CHU, and the Functional Rehabilitation Centres of Divio (Dijon) and Bregille (Besançon)
  • Age between 18 and 85 years.
  • Etiological examination carried out according to current recommendations (CT scan and/or MRI, Holter ECG and Holter blood pressure, Doppler of the supra-aortic trunks, echocardiography).
  • Patients referred to the PMR unit less than one month after the cerebral vascular accident.
  • Clinical status considered stable from a cardiovascular and neurological point of view with a well-balanced medical treatment (anti-hypertensives, anti-coagulants or antiplatelets, oral antidiabetics if necessary)
  • Patients able to understand the instructions and the interest of retraining.
  • Patients who have provided written informed consent for the study.

Exclusion Criteria:

  • Existence of disorders associated with hemiplegic motor impairment: disorders of memory and superior functions (MMSE < 24) and impaired ability to understand (BDAE <3), deep sensitivity disorders, severe unilateral neglect (bells test).
  • Patients referred following meningeal hemorrhage or deep vein thrombosis
  • Recurrent stroke, whatever the severity of the sequelae of the previous stroke.
  • Existence of cerebellar involvement as a major aspect of the clinical picture
  • Myocardial infarction or heart surgery within the preceding 6 months.
  • Severe heart failure (NYHA >3 or left ventricular ejection fraction (LVEF) <40%).
  • Subjects presenting with complete non-stabilized arrhythmia
  • Any metabolic, infectious, inflammatory, respiratory or cardiovascular disease that is not stabilized or constitutes a contra indication to retraining (chronic respiratory insufficiency (obstructive or restrictive), severe valve disease, obstructive heart disease, severe progressive heart rhythm or conduction disorders, intracavitary thrombus.
  • Symptomatic peripheralartery disease (Leriche and Fontaine stage 3 or 4).
  • Any other debilitating neurological disease (multiple sclerosis, Parkinson's disease).
  • Participation in another biomedical research protocol during the retraining period (8 weeks minimum)
  • Patients under guardianship or ward of court.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Kohorter og intervensjoner

Gruppe / Kohort
The control group
will receive support "traditional"10 hours per week: techniques called neuro-facilitators
test group
enjoy the same support as control group at 7 hours week, coupled with a personalized retraining effort ergometer for 3 hours per week: after a 5 minute warm to 50% of Heart Rate Maximum (HRmax) of the initial test effort (TE), continuous work of 20 minutes at an intensity corresponding to 70% HRmax, followed by a recovery period of 5 min between active 40 and 50% of maximum heart rate (5 times per week).

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Neuromotor capacity
Tidsramme: participants will be followed for the duration of hospital stay, an expected average of 12 months

The walking speed of 10 meters.

  • The level of disability by the scale of the Functional Independence Measure (FIM) - Functional walking ability, assessed clinically by Functional Ambulation Classification (FAC), as amended to Month 2 and Month 6.
  • The ability to balance by static posturography: a collection of the path length not the center of the plantar pressure stabilogram.
participants will be followed for the duration of hospital stay, an expected average of 12 months
functional capacity
Tidsramme: participants will be followed for the duration of hospital stay, an expected average of 12 months

The walking speed of 10 meters.

  • The level of disability by the scale of the Functional Independence Measure (FIM) - Functional walking ability, assessed clinically by Functional Ambulation Classification (FAC), as amended to Month 2 and Month 6.
  • The ability to balance by static posturography: a collection of the path length not the center of the plantar pressure stabilogram.
participants will be followed for the duration of hospital stay, an expected average of 12 months

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. mai 2010

Primær fullføring (Faktiske)

1. september 2011

Studiet fullført (Faktiske)

1. september 2011

Datoer for studieregistrering

Først innsendt

17. juli 2013

Først innsendt som oppfylte QC-kriteriene

24. juli 2013

Først lagt ut (Anslag)

25. juli 2013

Oppdateringer av studieposter

Sist oppdatering lagt ut (Anslag)

25. juli 2013

Siste oppdatering sendt inn som oppfylte QC-kriteriene

24. juli 2013

Sist bekreftet

1. juli 2013

Mer informasjon

Begreper knyttet til denne studien

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

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