评估偏头痛白质高信号的研究
偏头痛中的白质高信号：用于疾病病理学分类的多模态成像项目
The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习地点
-
-
Arizona
-
Phoenix、Arizona、美国、85054
- Mayo Clinic in Arizona
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria - Migraine (N=20):
- Female only.
- Ages 20-45 years.
- Presence of WMH on MRI.
Exclusion Criteria:
- History of SVI and/or history of MS or other neurological disease other than migraine.
- History of cancer or organ transplantation.
- Contraindication to MRI.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study.
Inclusion Criteria - SVI disease (n=10):
- Female only
- Ages > 60 years.
- Presence of WMH on MRI.
Exclusion Criteria:
- History of migraine and/or history of MS or other neurological disease other than SVI.
- History of cancer or organ transplantation.
- History of abnormal brain MRI other than WMH.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study.
Inclusion Criteria - MS (n=10):
- Female only.
- Ages 20-45.
- Presence of WMH on MRI.
Exclusion Criteria:
- History of migraine and/or history of SVI or other neurological disease other than MS.
- History of cancer or organ transplantation.
- History of abnormal brain MRI other than WMH.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study.
学习计划
研究是如何设计的？
设计细节
- 主要用途：诊断
- 分配：非随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
其他：Migraine cohort
Women with migraine and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging. |
Non-invasive magnetic resonance imaging sequences will investigate metabolic signatures unique to migraine WMH. Imaging data will be used for development of artificial intelligence (AI) algorithms to classify the cause of WMHs. |
|
其他：Small vessel ischemic (SVI) disease cohort
Women diagnosed with SVI disease and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging. |
Non-invasive magnetic resonance imaging sequences will investigate metabolic signatures unique to migraine WMH. Imaging data will be used for development of artificial intelligence (AI) algorithms to classify the cause of WMHs. |
|
其他：Multiple sclerosis (MS) cohort
Women diagnosed with MS and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging. |
Non-invasive magnetic resonance imaging sequences will investigate metabolic signatures unique to migraine WMH. Imaging data will be used for development of artificial intelligence (AI) algorithms to classify the cause of WMHs. |
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
WMH imaging disease parameters
大体时间：3 months
|
Radiological MRI assessment of WMH in migraine |
3 months
|
合作者和调查者
赞助
调查人员
- 首席研究员：Catherine Chong, PhD、Mayo Clinic
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.