胃 MALT 淋巴瘤队列研究 (HUG-MALToma)
建立胃 MALT 淋巴瘤病理生理学研究队列
The goal of this observational study is to establish clinical data and tissue repository in patients with gastric MALT lymphoma and controls.
Participants will be asked to provide clinical information and various tissues (saliva, gastric mucosa, and feces).
研究概览
研究类型
注册 (估计的)
联系人和位置
学习地点
-
-
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Seoul、韩国、03181
- 招聘中
- Kangbuk Samsung Hospital
-
接触：
- Hyo-Joon Yang, MD. PhD.
- 电话号码：82-2-2001-8330
- 邮箱：hyojoon.yang@samsung.com
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Gyeonggi-do
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Ansan-si、Gyeonggi-do、韩国、15355
- 尚未招聘
- Korea University Ansan Hospital
-
接触：
- Ayoung Lee, MD. PhD.
- 电话号码：82-31-412-5114
- 邮箱：frisby@naver.com
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Seongnam-si、Gyeonggi-do、韩国、463-707
- 招聘中
- Cheol Min Shin
-
接触：
- Cheol Min Shin, M.D., Ph.D.
- 电话号码：+ 82-31-787-7057
- 邮箱：scm6md@gmail.com
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-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
Eligible patients who visited participating hospital will be asked, and upon providing informed consent, will be enrolled in the study.
描述
Inclusion Criteria:
[MALT lymphoma group]
-
Newly diagnosed as gastric MALT lymphoma [Control group]
-
Patients who underwent
- diagnosed upper endoscopy for dyspepsia and had chronic gastritis,
- therapeutic upper endoscopy for gastric hyperplastic polyps, or
- screening upper endoscopy without any symptoms.
Exclusion Criteria:
- History of gastric or other malignancy
- Use of antibiotics or probiotics within 4 weeks
- Uncontrolled chronic illnesses
学习计划
研究是如何设计的？
设计细节
- 观测模型：COHORT
- 时间观点：PROSPECTIVE
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
MALT lymphoma
Patients who were newly diagnosed as gastric MALT lymphoma |
New diagnosis with gastric MALT lymphoma |
|
Control group
Patients who underwent
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Remission of gastric MALT lymphoma
大体时间：Within 3 years from diagnosis
|
Remission of gastric MALT lymphoma |
Within 3 years from diagnosis
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Eradication of H. pylori infection
大体时间：Within 6 month from eradication therapy
|
Eradication of H. pylori infection |
Within 6 month from eradication therapy
|
合作者和调查者
出版物和有用的链接
一般刊物
- Di Rocco A, Petrucci L, Assanto GM, Martelli M, Pulsoni A. Extranodal Marginal Zone Lymphoma: Pathogenesis, Diagnosis and Treatment. Cancers (Basel). 2022 Mar 29;14(7):1742. doi: 10.3390/cancers14071742.
- Tanaka T, Matsuno Y, Torisu T, Shibata H, Hirano A, Umeno J, Kawasaki K, Fujioka S, Fuyuno Y, Moriyama T, Esaki M, Kitazono T. Gastric microbiota in patients with Helicobacter pylori-negative gastric MALT lymphoma. Medicine (Baltimore). 2021 Sep 24;100(38):e27287. doi: 10.1097/MD.0000000000027287.
- Lemos FFB, Silva Luz M, Rocha Pinheiro SL, Teixeira KN, Freire de Melo F. Role of non-Helicobacter pylori gastric Helicobacters in helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma. World J Gastroenterol. 2023 Aug 28;29(32):4851-4859. doi: 10.3748/wjg.v29.i32.4851.
- Zucca E, Arcaini L, Buske C, Johnson PW, Ponzoni M, Raderer M, Ricardi U, Salar A, Stamatopoulos K, Thieblemont C, Wotherspoon A, Ladetto M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Marginal zone lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020 Jan;31(1):17-29. doi: 10.1016/j.annonc.2019.10.010. Epub 2019 Dec 4. No abstract available.
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- HUG-MALToma
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
IPD 计划说明
IPD will not be shared due to data protection policy of the participating institutions.
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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