WISSPR研究的混合方法协议 (WiSSPr)
WISSPR研究的混合方法方案：赞比亚的性工作，污名和心理心理障碍的妇女
WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry of Health (MoH).
研究概览
详细说明
WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry of Health (MoH). The study will administer a one-time psychosocial survey vetted by the CAB and follow 300 WESW in the electronic medical record for three months to measure PrEP initiation (#/% ever taking PrEP) and persistence (immediate discontinuation and a medication possession ratio). The study will conduct in-depth interviews with a purposive sample of 18 women, including 12 WESW and 6 peer navigators who support routine HIV screening and PrEP delivery, in two community hubs serving KPs since October 2021. The study seeks to value KP communities as equal contributors to the knowledge production process by actively engaging KP-CSOs throughout the research process. Expected outcomes include quantitative measures of PrEP initiation and persistence among WESW, and qualitative insights into the enablers and barriers to PrEP use informed by participants' lived experiences. https://doi.org/10.1136/bmjopen-2023-080218
研究类型
注册 (实际的)
联系人和位置
学习地点
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Lusaka、赞比亚
- Centre for Infectious Disease Research Zambia
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
The study population is composed of adult WESW who are living or working within the catchment areas of two community hubs located within urban Lusaka. Based on CIDRZ's prior published work, we anticipate that the study population will be comprised largely (63%) of younger women (18 - 29 years old).
描述
Inclusion Criteria
Participants must meet all of the following criteria:
- Identify as a cisgender or transgender woman.
- Be 18 years of age or older.
- Earn a significant amount of income from exchanging sex for money or goods within the last 3 months.
- Be HIV-negative and eligible for PrEP according to national guidelines.
- Not be planning to transfer care to another site within the next 30 days.
- Speak English, ChiNyanja, or IchiBemba.
- Be willing and able to provide written informed consent.
Exclusion Criteria
Participants will be excluded if they meet any of the following criteria:
- Do not identify as a woman.
- Are under 18 years of age.
- Have not earned a significant amount of income from exchanging sex for money or goods, or have done so for less than 3 months.
- Are HIV-positive, have an unknown HIV status, or are ineligible for PrEP.
- Are planning to transfer care to another site within the next 30 days.
- Are unable to speak English, ChiNyanja, or IchiBemba.
- Are unwilling or unable to provide written informed consent.
学习计划
研究是如何设计的？
设计细节
- 观测模型：COHORT
- 时间观点：PROSPECTIVE
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
PrEP initiators
women who initiate on PrEP |
oral PrEP |
|
PrEP refusers
women who refuse PrEP |
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
PrEP initiation (#/% ever taken PrEP)
大体时间：3 months
|
PrEP initiation (Number or percentage of Women Engaging in Sex Work (WESW) initiating on PrEP) |
3 months
|
|
PrEP Persistence (#/ % eligible refills obtained until first discontinuation)
大体时间：3 months
|
PrEP persistence. Number or percentage of women engaging in sex work with high levels of stigma who will persist on PrEP |
3 months
|
合作者和调查者
调查人员
- 首席研究员：Ramya Kumar, PhD, MPH、University of Washington
出版物和有用的链接
有用的网址
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- UJMT Fogarty Fellowship 2023
- D43TW009340 (美国 NIH 拨款/合同)
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
IPD 计划说明
Vulnerable population of sex workers in a country where sex work is largely criminalized, and there is a risk of harm if the data is identifiable even with common identifiers like name is removed.
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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