Study of Prognostic Factors in Adult Lymphoblastic Lymphoma

January 31, 2022 updated by: PETHEMA Foundation

FPLLA-PETHEMA-001: Study of Prognostic Factors in Adult Lymphoblastic Lymphoma

Retrospective observational study with systematic collection of data on filiation (age at diagnosis and sex), clinical data (IPI, ECOG, early response to chemotherapy, overall response to chemotherapy), biological (strain B or T, infiltration of the nervous system central [CNS], bone marrow [MO], lactate dehydrogenase (LDH) level at the time of diagnosis, as well as genetic patients included in the study, as well as the PETHEMA protocol used in the treatment of same patients The study will review the PETHEMA protocols from 2003 to the present

Study Overview

Status

Status

Indicates the current recruitment status or the expanded access status.
Recruiting

Conditions

Conditions

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.

Detailed Description

Retrospective observational study with systematic collection of data on filiation (age at diagnosis and sex), clinical data (IPI, ECOG, early response to chemotherapy, overall response to chemotherapy), biological (strain B or T, infiltration of the nervous system central [CNS], bone marrow [MO], lactate dehydrogenase (LDH) level at the time of diagnosis, as well as genetic patients included in the study, as well as the PETHEMA protocol used in the treatment of same patients The study will review the PETHEMA protocols from 2003 to the present. Analysis of the main clinical-biological variables as independent risk factors in adult patients (> 15 years) diagnosed with ALL

Study Type

Study Type

Describes the nature of a clinical study. Study types include interventional studies (also called clinical trials), observational studies (including patient registries), and expanded access.
Observational

Enrollment (Anticipated)

Enrollment

The number of participants in a clinical study. The "anticipated" enrollment is the target number of participants that the researchers need for the study.
30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact

The name and contact information for the person who can answer enrollment questions for a clinical study. Each location where the study is being conducted may also have a specific contact, who may be better able to answer those questions.

Study Contact Backup

Study Locations

  • Spain
      • Alicante, Spain
        • Recruiting
        • Hospital General de Alicante
        • Contact:
          • Cristina Gil
      • Barcelona, Spain
        • Recruiting
        • Hospital Clinic de Barcelona
        • Contact:
          • Jordi Esteve
      • Barcelona, Spain
        • Recruiting
        • H. de La Santa Creu I Sant Pau
        • Contact:
          • Irene García Cadenas
      • Barcelona, Spain
        • Recruiting
        • H. Vall d'Hebron, Barcelona
        • Contact:
          • Pere Barba
      • Barcelona, Spain
        • Recruiting
        • H.Universitari Germans Trias I Pujol de Badalona
        • Contact:
          • Josep Maria Ribera
      • Basurto, Spain
        • Recruiting
        • Hospital de Basurto
        • Contact:
          • Cristina Barrenetxea Lekue
      • Bellvitge, Spain
        • Recruiting
        • ICO-Duran i Reynals
        • Contact:
          • Santiago Mercadal
      • Donostia, Spain
        • Recruiting
        • Hospital Donostia
        • Contact:
          • Teresa Artola
      • Girona, Spain
        • Recruiting
        • H. Univ. de Girona Dr. Josep Trueta (ICO)
        • Contact:
          • Rosa Coll
      • Lleida, Spain
        • Recruiting
        • Hospital Arnau de Vilanova (Lleida)
        • Contact:
          • Antoni Garcia-Guiñon
      • Lugo, Spain
        • Recruiting
        • Hospital Lucus Augusti
        • Contact:
          • María José Sánchez Sánchez
      • Madrid, Spain
        • Recruiting
        • H. Gregorio Marañón
        • Contact:
          • Silvia Monsalvo
      • Murcia, Spain
        • Recruiting
        • Hospital General Universitario Morales Messeguer
        • Contact:
          • Maria Luz Amigo
      • Málaga, Spain
        • Recruiting
        • Hospital San Pedro de Alcántara.
        • Contact:
          • Bergua Juan, Dr
      • Palma De Mallorca, Spain
        • Recruiting
        • Hospital Son Espases
        • Contact:
          • Andrés Novo
      • Palma de Mallorca, Spain
        • Recruiting
        • Hospital Son Llatzer
        • Contact:
          • Antònia Cladera
      • Pamplona, Spain
        • Recruiting
        • Complejo Hospitalario de Navarra
        • Contact:
          • Maria Carmen Mateos Rodríguez
      • Sabadell, Spain
        • Recruiting
        • Parc Taulí
        • Contact:
          • Sonia Piernas
      • Salamanca, Spain
        • Recruiting
        • H. Univ. de Salamanca
        • Contact:
          • Jesús Maria Hernández Rivas
      • Santiago de Compostela, Spain
        • Recruiting
        • C. H. U. de Santiago
        • Contact:
          • Natalia Alonso, Dr
      • Sevilla, Spain, 41013
        • Recruiting
        • Complejo Hosp. Regional Virgen del Rocío
        • Contact:
          • José González Campos, Dr
      • Sevilla, Spain
        • Recruiting
        • Hospital del Valme
        • Contact:
          • Maria Ángeles Domínguez
      • Tarragona, Spain
        • Recruiting
        • H. Joan XXIII
        • Contact:
          • Marta Cervera
      • Valencia, Spain
        • Recruiting
        • Hoapital La Fe
        • Contact:
          • Pau Montesinos
      • Valencia, Spain
        • Recruiting
        • Hospital Arnau de Vilanova (Valencia)
        • Contact:
          • Aurelio López
      • Valencia, Spain
        • Recruiting
        • Hospital Universitari Clínic València
        • Contact:
          • Mar Tormo
    • Asturias
      • Oviedo, Asturias, Spain
        • Recruiting
        • Hospital Central de Asturias
        • Contact:
          • Teresa Bernal
    • Barcelona
      • Terrassa, Barcelona, Spain
        • Recruiting
        • Hospital Mútua de Terrassa
        • Contact:
          • Ferran Vall-Llovera

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Eligibility Criteria

The key requirements that people who want to participate in a clinical study must meet or the characteristics they must have. Eligibility criteria consist of both inclusion criteria (which are required for a person to participate in the study) and exclusion criteria (which prevent a person from participating). Types of eligibility criteria include whether a study accepts healthy volunteers, has age or age group requirements, or is limited by sex.

Ages Eligible for Study

15 years and older (Child, Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients> 15 years diagnosed with ALL and treated with the PETHEMA protocols for ALL

Description

Inclusion Criteria:

Patients >15 years old diagnosed with ALL and treated with the PETHEMA protocols for ALL

Exclusion Criteria:

None

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Only
  • Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Primary Outcome Measures

In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical studies have one primary outcome measure, but some have more than one.
Outcome Measure
Measure Description
Time Frame
Description pronostic factors
Time Frame: 1 year
Study of the main clinical-biological variables as independent risk factors in adult patients (> 15 years) diagnosed with ALL
1 year

Secondary Outcome Measures

Secondary Outcome Measures

In a clinical study's protocol, a planned outcome measure that is not as important as the primary outcome measure for evaluating the effect of an intervention but is still of interest. Most clinical studies have more than one secondary outcome measure.
Outcome Measure
Measure Description
Time Frame
overall survival
Time Frame: 1 year
To study if there has been an increase in overall survival (OS), in patients diagnosed with ALL in the different PETHEMA protocols
1 year
Progression free survival
Time Frame: 1 year
To study if there has been an increase in progression-free survival (PFS) in patients diagnosed with ALL in the different PETHEMA protocols
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sponsor

The organization or person who initiates the study and who has authority and control over the study.
PETHEMA Foundation

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

Study Start

The actual date on which the first participant was enrolled in a clinical study. The "anticipated" study start date is the date that the researchers think will be the study start date.
June 15, 2018

Primary Completion (Anticipated)

Primary Completion

The date on which the last participant in a clinical study was examined or received an intervention to collect final data for the primary outcome measure. Whether the clinical study ended according to the protocol or was terminated does not affect this date. For clinical studies with more than one primary outcome measure with different completion dates, this term refers to the date on which data collection is completed for all the primary outcome measures. The "anticipated" primary completion date is the date that the researchers think will be the primary completion date for the study.
December 30, 2022

Study Completion (Anticipated)

Study Completion

The date on which the last participant in a clinical study was examined or received an intervention/treatment to collect final data for the primary outcome measures, secondary outcome measures, and adverse events (that is, the last participant's last visit). The "anticipated" study completion date is the date that the researchers think will be the study completion date.
December 30, 2022

Study Registration Dates

First Submitted

First Submitted

The date on which the study sponsor or investigator first submitted a study record to ClinicalTrials.gov. There is typically a delay of a few days between the first submitted date and the record's availability on ClinicalTrials.gov (the first posted date).
June 18, 2018

First Submitted That Met QC Criteria

First Submitted That Met QC Criteria

The date on which the study sponsor or investigator first submits a study record that is consistent with National Library of Medicine (NLM) quality control (QC) review criteria. The sponsor or investigator may need to revise and submit a study record one or more times before NLM's QC review criteria are met. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
June 18, 2018

First Posted (Actual)

First Posted

The date on which the study record was first available on ClinicalTrials.gov after National Library of Medicine (NLM) quality control (QC) review has concluded. There is typically a delay of a few days between the date the study sponsor or investigator submitted the study record and the first posted date.
June 28, 2018

Study Record Updates

Last Update Posted (Actual)

Last Update Posted

The most recent date on which changes to a study record were made available on ClinicalTrials.gov. There may be a delay between when the changes were submitted to ClinicalTrials.gov by the study's sponsor or investigator (the last update submitted date) and the last update posted date.
February 1, 2022

Last Update Submitted That Met QC Criteria

Last Update Submitted That Met QC Criteria

The most recent date on which the study sponsor or investigator submitted changes to a study record that are consistent with National Library of Medicine (NLM) quality control (QC) review criteria. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
January 31, 2022

Last Verified

Last Verified

The most recent date on which the study sponsor or investigator confirmed the information about a clinical study on ClinicalTrials.gov as accurate and current. If a study with a recruitment status of recruiting; not yet recruiting; or active, not recruiting has not been confirmed within the past 2 years, the study's recruitment status is shown as unknown.
January 1, 2022

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

Other Study ID Numbers

Identifiers or ID numbers other than the NCT number that are assigned to a clinical study by the study's sponsor, funders, or others. These numbers may include unique identifiers from other trial registries and National Institutes of Health grant numbers.
  • FPLLA-PETHEMA-001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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