- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00042250
IUdR/BUdR Cell Cycle Labelling
January 20, 2012 updated by: M.D. Anderson Cancer Center
Cell Cycle Kinetics in Vivo in Patients With Hematologic Malignancies Studied by Iododeoxyuridine and Bromodeoxyuridine Labelling
To determine cell cycle parameters and changes after treatment, the labelling agent is given and a bone marrow aspiration is accomplished before treatment and after treatment for comparison.
Participants must be undergoing concurrent therapy for hematologic malignancy.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Cell cycle parameters include LI, Ts, Tc, T dpot, changes in these parameters, and differences between normal and leukemic cells in patients with hematologic malignancy prior to and following treatment.
Study Type
Interventional
Enrollment (Actual)
28
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Texas
-
Houston, Texas, United States, 77030
- M.D. Anderson Cancer Center
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Histologic proof of one of:
- AML, ALL, or AUL
- MDS or CMML
- CML
- OR undergoing bone marrow transplantation.
Participants should be:
- off therapy for at least two weeks
- At least 18 years old or older
- Using adequate contraception if of child-bearing capability.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Diagnostic
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Chair: Michael Andreeff, MD, PhD, M.D. Anderson Cancer Center
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 1992
Primary Completion (Actual)
October 1, 2002
Study Completion (Actual)
October 1, 2002
Study Registration Dates
First Submitted
July 24, 2002
First Submitted That Met QC Criteria
July 25, 2002
First Posted (Estimate)
July 26, 2002
Study Record Updates
Last Update Posted (Estimate)
January 24, 2012
Last Update Submitted That Met QC Criteria
January 20, 2012
Last Verified
January 1, 2012
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- DM91-102
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Hematologic Malignancies
-
Cooperative Study Group A for HematologyCompletedHEMATOLOGIC MALIGNANCIESKorea, Republic of
-
Fondazione EMN Italy OnlusCompletedHEMATOLOGIC MALIGNANCIESItaly
-
Washington University School of MedicineRecruitingPediatric Hematologic MalignanciesUnited States
-
Medical College of WisconsinCompletedMalignancies, HematologicUnited States
-
Sinocelltech Ltd.RecruitingRelapsed or Refractory Hematologic MalignanciesChina
-
Vanda PharmaceuticalsUnknownRelapsed or Refractory Hematologic MalignanciesUnited States
-
University of UtahTerminatedHigh Risk Hematologic MalignanciesUnited States
-
King Faisal Specialist Hospital & Research CenterCompletedTransplantation for Hematologic MalignanciesSaudi Arabia
-
Precision BioSciences, Inc.RecruitingHematologic Malignancy | CD19 Expressing MalignanciesUnited States
-
University of California, DavisCompletedHematologic MalignanciesUnited States
Clinical Trials on Chemotherapy for hematologic malignancy
-
University Hospital, MontpellierRecruiting
-
Center for International Blood and Marrow Transplant...National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaboratorsCompletedHematologic MalignancyUnited States
-
Janssen Korea, Ltd., KoreaCompletedNeutropenia | Fever | Hematological Malignancies
-
University of PadovaCompleted
-
Skin Analytics LimitedCompletedBasal Cell Carcinoma | Squamous Cell Carcinoma | Malignant Skin Melanoma T0United States, Italy
-
Skin Analytics LimitedInnovate UKCompleted
-
Skin Analytics LimitedInnovate UKCompleted
-
Sohag UniversityCompletedRenal Disorder Associated With Type II Diabetes MellitusEgypt
-
Dana-Farber Cancer InstitutePatient-Centered Outcomes Research Institute; National Cancer Institute (NCI); Alliance for Clinical Trials in OncologyCompletedMetastatic Colorectal Cancer | Metastatic Pancreatic Cancer | Unresectable Pancreatic CancerUnited States
-
Centro Hospitalar NordesteCompletedColorectal Cancer