Interaction of Caffeine and Hydration on Voice

June 10, 2013 updated by: Southern Illinois University Carbondale

Effects of the Interaction of Caffeine and Hydration on Voice Performance

The purpose of the study, Effects of Interaction of Caffeine and Hydration on Voice Performance, is to gather information about the effects of caffeine and hydration upon voice performance. The research question involves whether systemic hydration may reduce degradation on voice performance caused by caffeine ingestion. It is hypothesized that the hydration conditions will result in a less degraded vocal performance as compared with the nonhydration condition.The investigation involves abstention from any caffeine ingestion for 24 hours - from 8pm the day before testing to 8am the morning of testing. In addition, preparation for participation involves abstaining from ingesting any foods and liquids for 12 hours - from 8pm to 8am of the following morning. Each test will take about 10 minutes.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The objective of this investigation is to explore the interaction of water and caffeine on voice performance through (a) acoustic measures of voice, and (b) aerodynamic measurements (minimum lung pressure required to initiate phonation. The acoustic and aerodynamic measurements were selected for this study in an effort to demonstrate the effects of four levels of hydration and caffeine status on voice quality: 1) caffeine and water1 (i.e.., Experimental Group 1 - ingestion of 200 mg of caffeine in conjunction with 500 ml of water), 2) caffeine and water2 (i.e., Experimental Group 2 - ingestion of 200 mg of caffeine in conjunction with 1.0 liter of water), 3)caffeine only (i.e., Experimental Group 3: ingestion of 200 mg of caffeine and no water), and 4) control (i.e. no ingestion of caffeine or water). The research question involves whether systemic hydration may reduce degradation on voice performance caused by caffeine ingestion. It is hypothesized that the hydration conditions will result in a less degraded vocal performance as compared with the nonhydration condition. Additionally, it is hypothesized that ingestion of 1.0 liter of water will have a greater effect on voice performance than ingestion of 500 ml of water. An additional objective of this study is to increase scientific knowledge of voice functioning by providing further data about the effect of the interaction of water and caffeine on voice performance. The results of this project may be a valuable addition to the scientific literature in vocology, and may also contribute to prevention plans for minimizing vocal disturbances. Therefore, vocational programs may include vocal prevention directions based on this study. In addition, knowledge about prevention of voice disorders may be included in the academic curriculum of students enrolled in training programs for professions involving substantial voice use.

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Early Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Illinois
      • Carbondale, Illinois, United States, 62901
        • Southern Illinois University Carbondale

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 35 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Healthy individuals, ranging from 18 to 35 years of age.

Exclusion Criteria:

  • History of voice disorders, history of coronary disease, history of high blood pressure.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: BASIC_SCIENCE
  • Allocation: RANDOMIZED
  • Interventional Model: FACTORIAL
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Caffeine and hydration.

200 mg of caffeine (over the counter caffeine tablet)

1 liter of water
Drug: C2 (200mg of caffeine; 1/2 L of water)
200mg of caffeine (tablet); 1/2 of water
Other Names:
  • Caffeine and water 2.
Drug: C3(200mg of caffeine; 1 L of water)
Ingestion of 200 mg of caffeine and 1 Liter of water after between pretest and posttest.
Other Names:
  • Caffeine and water 3.
Drug: C1 (200mg of caffeine, no water)
Ingestion of 200mg of caffeine (tablet); no water ingestion.
Other Names:
  • Caffeine
Drug: Placebo (no caffeine, no water).
No ingestion of caffeine; no ingestion of water between pretest and posttest.
Other Names:
  • Control.
PLACEBO_COMPARATOR: No caffeine, no hydration.
Drug: C2 (200mg of caffeine; 1/2 L of water)
200mg of caffeine (tablet); 1/2 of water
Other Names:
  • Caffeine and water 2.
Drug: C3(200mg of caffeine; 1 L of water)
Ingestion of 200 mg of caffeine and 1 Liter of water after between pretest and posttest.
Other Names:
  • Caffeine and water 3.
Drug: C1 (200mg of caffeine, no water)
Ingestion of 200mg of caffeine (tablet); no water ingestion.
Other Names:
  • Caffeine
Drug: Placebo (no caffeine, no water).
No ingestion of caffeine; no ingestion of water between pretest and posttest.
Other Names:
  • Control.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effect of caffeine and hydration on acoustic measures of voice.
Time Frame: 1 year
The acoustic measurement of voice include the parameters of relative average perturbation (RAP), shimmer, and sound pressure level (SPL).
1 year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effect of caffeine and hydration on aerodynamic measures of voice. Effect of caffeine and hydration on aerodynamic measures of voice.
Time Frame: 1 year
The aerodynamic measurement of voice includes the parameter of airflow. Airflow measurements refer to the amount of air passing through the region of the vocal folds decibels.
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Southern Illinois University Carbondale

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2010

Primary Completion (ACTUAL)

May 1, 2013

Study Completion (ACTUAL)

May 1, 2013

Study Registration Dates

First Submitted

September 24, 2010

First Submitted That Met QC Criteria

September 16, 2011

First Posted (ESTIMATE)

September 19, 2011

Study Record Updates

Last Update Posted (ESTIMATE)

June 11, 2013

Last Update Submitted That Met QC Criteria

June 10, 2013

Last Verified

June 1, 2013

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 09433

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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