Treatment of Subclinical Hyperthyroidism

September 25, 2020 updated by: University Hospital, Strasbourg, France

Place de l'Iode RadioActif Dans l'HyperThyroïdiE Sub-clinique (PIRHATES)/ Evaluation of the Interest of Subclinical Hyperthyroidism Treatment

Objective: To determine if the treatment of subclinical hyperthyroidism will reduce the rate of atrial fibrillation, the main complication of this condition.

Study Overview

Status

Terminated

Conditions

Detailed Description

Randomized open-labelled multicentre study comparing radioiodine vs medical supervision without treatment

Study Type

Observational

Enrollment (Actual)

145

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Bordeaux, France
        • Patrick Roger
      • Clermont-Ferrand, France
        • Philippe Thiéblot
      • Dijon, France
        • Jean-Marcel Brun
      • Lille, France
        • Jean-Louis Wemeau
      • Limoges, France
        • Marie-Pierre Teissier
      • Lyon, France
        • Jacques Orgiazzi
      • Marseille, France
        • Bernard Conte-Delvox
      • Montbrison, France, 42605
        • CH de MONTBRISON
      • Montpellier, France
        • Jacques Bringer
      • Nancy, France
        • Marc Klein
      • Nimes, France
        • Michel Rodier
      • Paris, France
        • Laurence Leenhardt
      • Poitiers, France
        • Richard Marechaud
      • Reims, France
        • Brigitte Delemer
      • Reims, France
        • Claire Schvartz
      • Rouen, France
        • Jean-Marc Kuhn
      • Saint-Etienne, France
        • Bruno Estour
      • Strasbourg, France
        • Hopitaux Universitaires de Strasbourg
      • Strasbourg, France, 67000
        • Centre Paul Strauss
      • Toulouse, France
        • Philippe Caron
      • Tours, France
        • Pierre Lecomte

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

patients referred to tertiary hospitals for advice on thyroïd disease

Description

Inclusion Criteria:

  • Men and women aged 50 and greater
  • Isolated decreased thyroid-stimulating hormone (TSH) with normal FT4 and FT3 levels

Exclusion Criteria:

  • Iodide overload
  • Non sinusal heart rhythm
  • Severe heart disease

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Strasbourg, France

Investigators

  • Principal Investigator: Bernard Goichot, MD, Hopitaux Universitaires de Strasbourg

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

August 1, 2005

Primary Completion (Actual)

November 1, 2019

Study Completion (Actual)

January 1, 2020

Study Registration Dates

First Submitted

September 13, 2005

First Submitted That Met QC Criteria

September 13, 2005

First Posted (Estimate)

September 21, 2005

Study Record Updates

Last Update Posted (Actual)

September 29, 2020

Last Update Submitted That Met QC Criteria

September 25, 2020

Last Verified

August 1, 2019

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 3463

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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