- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00349882
Effects of Contact Lens Care Regimens on the Corneal Epithelium
July 5, 2006 updated by: University of Waterloo
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment
30
Phase
- Phase 4
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Ontario
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Waterloo, Ontario, Canada, N2L 3G1
- Centre for Contact Lens Research, University of Waterloo
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
16 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Is at least 18 years old and has full legal capacity to volunteer.
- Has read, understood and signed an Information Consent Letter.
- Is willing and able to follow instructions and maintain the appointment schedule.
- Is correctable to a visual acuity of 6/6 or better (each eye), with their habitual visual correction.
- Has normal binocular vision (no strabismus, no amblyopia, and anisometropia less than or equal to 1.00 D).
- Has clear corneas and no active ocular disease.
- Has had an ocular examination in the last 2 years.
Has not worn contact lenses before, or has worn contact lenses only for a trial period, with no trials occurring within the last six months.
An ineligible contact lens wearer is one who:
- Responds positively to points 1 to 7 above.
- Has a distance contact lens prescription between -0.50D and -9.00 D.
- Has astigmatism less than or equal to -1.00D cyl.
- Currently wears silicone hydrogel contact lenses successfully.
- Agrees to wear the study lenses on a daily wear basis without the use of ocular or lens lubricants.
Exclusion Criteria:
- Has undergone corneal refractive surgery.
- Is aphakic.
- Has any active ocular disease.
- Has any systemic disease affecting ocular health.
- Is using any systemic or topical medications that may affect ocular health.
- Has known sensitivity to the diagnostic pharmaceuticals to be used in the study.
- Is pregnant or lactating.
Is participating in any other type of clinical or research study.
An ineligible contact lens wearer is one who:
- Responds positively to any of points 1 to 8 above for exclusion criteria.
- Has known sensitivity to the contact lens care solutions used in the study.
- Has ocular or systemic allergies that could adversely affect contact lens wear.
- Has any ocular pathology or severe insufficiency of lacrimal secretion (dry eyes) that would affect the wearing of contact lenses.
- Has pinguecula/pterygium that in the investigator's judgement makes contact lens wear inadvisable.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Double
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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The primary outcome measure of this study is to investigate the effects of two
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different contact lens care solutions on the cornea.
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Secondary Outcome Measures
Outcome Measure |
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The secondary outcome measure of this study is to compare the subjective and
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objective responses between two different contact lens care solutions.
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Craig Woods, PhD, University of Waterloo
- Principal Investigator: Desmond Fonn, MOptom, University of Waterloo
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2005
Study Registration Dates
First Submitted
July 5, 2006
First Submitted That Met QC Criteria
July 5, 2006
First Posted (Estimate)
July 10, 2006
Study Record Updates
Last Update Posted (Estimate)
July 10, 2006
Last Update Submitted That Met QC Criteria
July 5, 2006
Last Verified
July 1, 2006
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- P/216/05/L
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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