- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00442091
Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.
The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
-
Odense, Denmark, DK-5000
- Department of Dermatology, Odense University Hospital
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.
Exclusion Criteria:
- Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
- Pregnancy, lactation.
- Compositae contact allergy.
- Liver or gall bladder disease.
- Abnormal renal or hepatic blood tests.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Other: 10 ml of dandelion juice twice daily
|
10 ml bid for 20-30 days
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.
Time Frame: 3-4 weeks
|
3-4 weeks
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).
Time Frame: 3-4 weeks
|
3-4 weeks
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Evy Paulsen, Dr., Department of Dermatology, Odense University Hospital, DK-5000 Odense C
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 20070010
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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