- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00824876
Orthostatic Tolerance in Mamma Cancer Patients After Anaesthesia
The investigators want to investigate the effect of anaesthesia, on the ability to maintain upright posture immediately after surgery in mamma cancer patients.
The investigators hypothesis is, that a standard anaesthesia does not effect the ability to maintain upright posture right after surgery.
Study Overview
Status
Conditions
Detailed Description
It is known, that patients undergoing major surgery have problems maintaining upright posture after major surgery. This can be due to fall in bloodpressure, with symptoms like dizziness, nausea/vomiting and fainting.
With this investigation, we want to prove that anaesthesia is not the decisive factor, in patients ability to maintain upright posture after surgery.
Study Type
Contacts and Locations
Study Locations
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Copenhagen, Denmark
- Dept of anesthesia 2041, ABD centre, Rigshospitalet, Blegdamsvej
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients having performed elective breast surgery
- Age between 18 and 70 years
- Patients who have given written consent to participate in the project after haven completely understood the contents and limitations of the protocol
Exclusion Criteria:
- Patients who do not understand or speak Danish
- Patients who have not signed the informed consent or the written authority pre-medication, except 1g paracetamol
- ASA > II
- Pregnant or breastfeeding
- Known to have Renal disease
- Known to have Psychiatric disorder (not considering the use of SSRI antidepressive)
- Need for crash induction or prone position
- Oesophageal varicoses
- Necrosis or cancer in: Mouth, Pharynx, Larynx or Oesophagus
- Coarctation or aneurism in the proximal Aorta
- Severe bleeding disease
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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To investigate orthostatic function, measured by Finapress
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Secondary Outcome Measures
Outcome Measure |
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To investigate the occurrence of postsurgery nausea/vomiting
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Collaborators and Investigators
Sponsor
Investigators
- Study Director: Henrik Kehlet, MD, Ph.D, dept of surgical patophysiology
Study record dates
Study Major Dates
Study Start
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- OT after mastectomy
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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