Statin Therapy Results in the Real World Practice in the Czech Republic (STEP)

August 29, 2011 updated by: AstraZeneca

Statins are the first choice treatment of dyslipidemia, a major contributor to cardiovascular diseases. Statins also have enough evidence to demonstrate decrease of morbidity and mortality from cardiovascular diseases. Even though statin therapy is effective treatment of dyslipidaemia not all patients reach the goal levels.

The aim of the study is to estimate proportion of patients who achieved the therapeutic goal (LDL-C. total cholesterol, HDL-C and triglycerides levels) after at least one year of a statin therapy.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Anticipated)

3253

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Czech Republic
      • Benesov, Czech Republic
        • Research Site
      • Beroun, Czech Republic
        • Research Site
      • Blansko, Czech Republic
        • Research Site
      • Bohumin, Czech Republic
        • Research Site
      • Boskovice, Czech Republic
        • Research Site
      • Brandys nad Labem, Czech Republic
        • Research Site
      • Brno, Czech Republic
        • Research Site
      • Ceska Lipa, Czech Republic
        • Research Site
      • Cheb, Czech Republic
        • Research Site
      • Chomutov, Czech Republic
        • Research Site
      • Chrudim, Czech Republic
        • Research Site
      • Decin, Czech Republic
        • Research Site
      • Domazlice, Czech Republic
        • Research Site
      • Dvur Kralove nad Labem, Czech Republic
        • Research Site
      • Frydek-Mistek, Czech Republic
        • Research Site
      • Havirov, Czech Republic
        • Research Site
      • Havlickuv Brod, Czech Republic
        • Research Site
      • Hradec Kralove, Czech Republic
        • Research Site
      • Hustopece, Czech Republic
        • Research Site
      • Ivancice, Czech Republic
        • Research Site
      • Jablonec nad Nisou, Czech Republic
        • Research Site
      • Jesenik, Czech Republic
        • Research Site
      • Jicin, Czech Republic
        • Research Site
      • Jihlava, Czech Republic
        • Research Site
      • Jindrichuv Hradec, Czech Republic
        • Research Site
      • Karlovy Vary, Czech Republic
        • Research Site
      • Karvina, Czech Republic
        • Research Site
      • Kladno, Czech Republic
        • Research Site
      • Kolin, Czech Republic
        • Research Site
      • Krnov, Czech Republic
        • Research Site
      • Kurim, Czech Republic
        • Research Site
      • Kutna Hora, Czech Republic
        • Research Site
      • Kyjov, Czech Republic
        • Research Site
      • Liberec, Czech Republic
        • Research Site
      • Litomerice, Czech Republic
        • Research Site
      • Louny, Czech Republic
        • Research Site
      • Melnik, Czech Republic
        • Research Site
      • Mestec Kralove, Czech Republic
        • Research Site
      • Mikulov, Czech Republic
        • Research Site
      • Milevsko, Czech Republic
        • Research Site
      • Mlada Boleslav, Czech Republic
        • Research Site
      • Moravska Trebova, Czech Republic
        • Research Site
      • Moravske Budejovice, Czech Republic
        • Research Site
      • Moravsky Krumlov, Czech Republic
        • Research Site
      • Most, Czech Republic
        • Research Site
      • Nachod, Czech Republic
        • Research Site
      • Novy Bydzov, Czech Republic
        • Research Site
      • Olomouc, Czech Republic
        • Research Site
      • Opava, Czech Republic
        • Research Site
      • Orlova, Czech Republic
        • Research Site
      • Ostrava, Czech Republic
        • Research Site
      • Ostrov nad Ohri, Czech Republic
        • Research Site
      • Pardubice, Czech Republic
        • Research Site
      • Pelhrimov, Czech Republic
        • Research Site
      • Pisek, Czech Republic
        • Research Site
      • Plzen, Czech Republic
        • Research Site
      • Police nad Metuji, Czech Republic
        • Research Site
      • Policka, Czech Republic
        • Research Site
      • Prachatice, Czech Republic
        • Research Site
      • Praha 1, Czech Republic
        • Research Site
      • Praha 10, Czech Republic
        • Research Site
      • Praha 2, Czech Republic
        • Research Site
      • Praha 3, Czech Republic
        • Research Site
      • Praha 4, Czech Republic
        • Research Site
      • Praha 5, Czech Republic
        • Research Site
      • Praha 6, Czech Republic
        • Research Site
      • Praha 8, Czech Republic
        • Research Site
      • Praha 9, Czech Republic
        • Research Site
      • Prerov, Czech Republic
        • Research Site
      • Prestice, Czech Republic
        • Research Site
      • Pribram, Czech Republic
        • Research Site
      • Prostejov, Czech Republic
        • Research Site
      • Rakovnik, Czech Republic
        • Research Site
      • Roudnice nad Labem, Czech Republic
        • Research Site
      • Roznov pod Radhostem, Czech Republic
        • Research Site
      • Rychnov nad Kneznou, Czech Republic
        • Research Site
      • Semily, Czech Republic
        • Research Site
      • Slany, Czech Republic
        • Research Site
      • Smirice, Czech Republic
        • Research Site
      • Sternberk, Czech Republic
        • Research Site
      • Strakonice, Czech Republic
        • Research Site
      • Susice, Czech Republic
        • Research Site
      • Svitavy, Czech Republic
        • Research Site
      • Tabor, Czech Republic
        • Research Site
      • Teplice, Czech Republic
        • Research Site
      • Tisnov, Czech Republic
        • Research Site
      • Trebic, Czech Republic
        • Research Site
      • Trinec, Czech Republic
        • Research Site
      • Trutnov, Czech Republic
        • Research Site
      • Turnov, Czech Republic
        • Research Site
      • Uherske Hradiste, Czech Republic
        • Research Site
      • Usti nad Labem, Czech Republic
        • Research Site
      • Valasske Klobouky, Czech Republic
        • Research Site
      • Veseli nad Moravou, Czech Republic
        • Research Site
      • Vitkovice, Czech Republic
        • Research Site
      • Vsetin, Czech Republic
        • Research Site
      • Vyskov, Czech Republic
        • Research Site
      • Vysoke Myto, Czech Republic
        • Research Site
      • Zamberk, Czech Republic
        • Research Site
      • Zlin, Czech Republic
        • Research Site
      • Znojmo, Czech Republic
        • Research Site
      • ceske Budejovice, Czech Republic
        • Research Site
      • cesky Krumlov, Czech Republic
        • Research Site

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

specialist care clinics

Description

Inclusion Criteria:

  • Documented statin therapy for at least 12 months
  • Available two LDL-C values: one at the beginning of statin therapy or at the time when patient comes to a specialist; and the other one at least after 12 months of treatment. The latter value should not be older than 6 months.

Exclusion Criteria:

-

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
LDL-C
Time Frame: one year
one year

Secondary Outcome Measures

Outcome Measure
Time Frame
Total cholesterol
Time Frame: one year
one year
HDL-C
Time Frame: one year
one year
triglycerides
Time Frame: one year
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

AstraZeneca

Investigators

  • Study Director: Ales Kminek, AstraZeneca
  • Principal Investigator: Jaromir Hradec, General faculty hospital Prague
  • Principal Investigator: Jan Bultas, Faculty hospital Kralovske Vinohrady Prague

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2010

Primary Completion (Actual)

June 1, 2010

Study Completion (Actual)

June 1, 2010

Study Registration Dates

First Submitted

January 25, 2010

First Submitted That Met QC Criteria

January 25, 2010

First Posted (Estimate)

January 26, 2010

Study Record Updates

Last Update Posted (Estimate)

August 30, 2011

Last Update Submitted That Met QC Criteria

August 29, 2011

Last Verified

August 1, 2011

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NIS-CCZ-CRE-2009/1

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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