American Joint Replacement Registry (AJRR)

The American Joint Replacement Registry is a not-for-profit 501(c)(3) organization for data collection and quality improvement initiatives for total hip and knee replacements. The AJRR is a collaborative effort supported by the American Academy of Orthopaedic Surgeons (AAOS), the American Association of Hip and Knee Surgeons (AAHKS), The Hip Society, The Knee Society, hospitals, health insurers, medical device manufacturers, and contributions from individual orthopaedic surgeons.

Study Overview

• Status: Recruiting
• Conditions: ARTHROPLASTY, REPLACEMENT

• Study Type: Observational
• Enrollment (Estimated): 500000

Contacts and Locations

• Study Contact: Name: Nathan Glusenkamp; Phone Number: 8473844028; Email: glusenkamp@aaos.org

Study Locations

• United States
  • Illinois
    • Rosemont, Illinois, United States, 60018
      • Recruiting
      • Nathan Glusenkamp
      • Contact: Nathan Glusenkamp; Phone Number: 8473844028; Email: glusenkamp@aaos.org
      • Contact: David G Lewallen, MD; Email: lewallen.david@mayo.edu
      • Principal Investigator: Nathan Glusenkamp

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

We expect to receive data on up to 90% of all total joint arthroplasties conducted in the United States annually.

Description

Inclusion Criteria:

• Any individual in the US undergoing total joint arthroplasty

Exclusion Criteria:

• None

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Health Related Quality of Life	Utilization of VR-12 and/or PROMIS-10	12 months

Secondary Outcome Measures

Outcome Measure	Time Frame
Hip disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)	12 months

Other Outcome Measures

Outcome Measure	Time Frame
Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)	12 months

Collaborators and Investigators

• Sponsor: American Joint Replacement Registry
• Investigators: Principal Investigator: Nathan Glusenkamp, American Joint Replacement Registry; Study Director: David G Lewallen, MD, American Joint Replacement Registry

Study record dates

Study Major Dates

• Study Start (Actual): August 1, 2011
• Primary Completion (Estimated): December 1, 2028
• Study Completion (Estimated): December 1, 2029

Study Registration Dates

• First Submitted: July 24, 2013
• First Submitted That Met QC Criteria: July 25, 2013
• First Posted (Estimated): July 26, 2013

Study Record Updates

• Last Update Posted (Estimated): October 3, 2025
• Last Update Submitted That Met QC Criteria: September 30, 2025
• Last Verified: September 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: 1120353

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: AJRR provides participating hospitals their data back in the form of dashboards and reports available on our registry platform. AJRR also releases an Annual Report every November which includes aggregate, de-identified data.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No