- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01986465
Effectiveness of Steroid Injection in Treating Patients With Lateral Epicondylitis
November 11, 2013 updated by: Amir Moayednia, Isfahan University of Medical Sciences
Comparing the Effectiveness of Steroid Injection Versus Placebo and Immobilization Versus no Immobilization in Treating Patients With Lateral Epicondylitis
The aim of this study is to evaluate the effectiveness of steroid injection and immobilization versus no immobilization in treating patients with lateral epicondylitis.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
78
Phase
- Phase 2
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Isfahan, Iran, Islamic Republic of
- Kashani University Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- age 18 to 65 years
- confirmed lateral epicondylitis
- had not received any treatment prior to enrolment
Exclusion Criteria:
- symptoms lasting less than 6 weeks
- history of acute trauma, fracture, and/or surgery within 12 months
- patients who had received corticosteroid injection, physiotherapy, splint or casting during the past 6 months
- bilateral involvement and history of cervical disk herniation, radiculopathy or abnormal electrophysiologic study
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Quadruple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Depomedrol
The trial pharmacist prepares a series of similar vials containing either 4 mg of Depomedrol or Normal Saline and coded them either 1, 2, 3 or 4, the group assignments are not decoded until the end of the trial when the final analysis is due to take place.
Patients take their envelopes to the trial pharmacist who give them a coded vial which they take to the orthopaedic surgeon who make the injection.
After the injection the trial clerk take the patients to a technician who give patients in groups 1 and 3 long arm splints.
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Placebo Comparator: Placebo
The trial pharmacist prepares a series of similar vials containing either 4 mg of Depomedrol or Normal Saline and coded them either 1, 2, 3 or 4, the group assignments are not decoded until the end of the trial when the final analysis is due to take place.
Patients take their envelopes to the trial pharmacist who give them a coded vial which they take to the orthopaedic surgeon who make the injection.
After the injection the trial clerk take the patients to a technician who give patients in groups 1 and 3 long arm splints.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Function
Time Frame: Within the first 24 weeks after therapy
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The trial subjects are evaluated using the Oxford Elbow Scale (OES).
They are asked to come to the trial office at 2 weeks, 4 weeks and 24 weeks for follow-up evaluation by administration of OES.
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Within the first 24 weeks after therapy
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Pain
Time Frame: Within the first 24 weeks after therapy
|
The trial subjects are evaluated using the Oxford Elbow Scale (OES).
They are asked to come to the trial office at 2 weeks, 4 weeks and 24 weeks for follow-up evaluation by administration of OES.
|
Within the first 24 weeks after therapy
|
Social-psychological
Time Frame: Within the first 24 weeks after therapy
|
The trial subjects are evaluated using the Oxford Elbow Scale (OES).
They are asked to come to the trial office at 2 weeks, 4 weeks and 24 weeks for follow-up evaluation by administration of OES.
|
Within the first 24 weeks after therapy
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Mohamad A Tahririan, MD, Isfahan University of Medical Sciences
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2013
Primary Completion (Actual)
November 1, 2013
Study Completion (Actual)
November 1, 2013
Study Registration Dates
First Submitted
November 11, 2013
First Submitted That Met QC Criteria
November 11, 2013
First Posted (Estimate)
November 18, 2013
Study Record Updates
Last Update Posted (Estimate)
November 18, 2013
Last Update Submitted That Met QC Criteria
November 11, 2013
Last Verified
November 1, 2013
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Wounds and Injuries
- Musculoskeletal Diseases
- Muscular Diseases
- Tendon Injuries
- Tendinopathy
- Arm Injuries
- Elbow Tendinopathy
- Tennis Elbow
- Physiological Effects of Drugs
- Autonomic Agents
- Peripheral Nervous System Agents
- Anti-Inflammatory Agents
- Antineoplastic Agents
- Antiemetics
- Gastrointestinal Agents
- Glucocorticoids
- Hormones
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Antineoplastic Agents, Hormonal
- Neuroprotective Agents
- Protective Agents
- Prednisolone
- Methylprednisolone Acetate
- Methylprednisolone
- Methylprednisolone Hemisuccinate
- Prednisolone acetate
- Prednisolone hemisuccinate
- Prednisolone phosphate
Other Study ID Numbers
- 387278
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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