the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension (CPETPH)

July 29, 2022 updated by: Chinese Pulmonary Vascular Disease Research Group
cardiopulmonary exercise test evaluate patients with pulmonary hypertension before and after medical or balloon pulmonary angioplasty treatment

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

patients diagnosed with pulmonary hypertension, including pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, will be evaluated by cardio pulmonary exercise test before and after medical or balloon pulmonary angioplasty treatment

Study Type

Observational

Enrollment (Anticipated)

4000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • China
      • Beijing, China, 100037
        • Recruiting
        • Center of pulmonary vascular disease, Fuwai hospital
        • Principal Investigator:
          • Zhihong Liu, MD,PhD
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

5 years to 100 years (Child, Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

pulmonary hypertension who may accomplish cardiopulmonary exercise testing.

Description

Inclusion Criteria:

  • pulmonary arterial hypertension;( WHO1)
  • chronic thromboembolic pulmonary hypertension;
  • pulmonary arterial hypertension due to other cause;

Exclusion Criteria:

  • massive hemoptysis;
  • unable to accomplish cardiopulmonary exercise testing due to neuromuscular disorders;
  • recent recurrent syncope;
  • pulmonary hypertension due to hypoxia;
  • pulmonary hypertension due to left heart diseases.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
cardiopulmonary exercise testing
patients diagnosed with pulmonary hypertension, including pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension, were evaluated by cardiopulmonary exercise testing before and after medical or balloon pulmonary angioplasty treatment
Device: balloon pulmonary angioplasty
patients with chronic thromboembolic pulmonary hypertension who underwent balloon pulmonary angioplasty

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
all cause mortality
Time Frame: 5 years
all cause mortality
5 years
mean pulmonary arterial pressure after treatment
Time Frame: 5 years
the mean pulmonary arterial pressure of patients with chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty treatment
5 years
achievement of low risk
Time Frame: 5 years
patients with chronic thromboembolic pulmonary hypertension achievement of low risk after balloon pulmonary angioplasty
5 years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
deterioration of WHO function
Time Frame: 5 years
deterioration of WHO function
5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Chinese Pulmonary Vascular Disease Research Group

Investigators

  • Study Director: Zhihong Liu, MD，PhD, Fuwai Hospital, National Center for Cardiovascular Diseases

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 1, 2010

Primary Completion (Anticipated)

September 8, 2030

Study Completion (Anticipated)

September 8, 2030

Study Registration Dates

First Submitted

February 11, 2014

First Submitted That Met QC Criteria

February 11, 2014

First Posted (Estimate)

February 13, 2014

Study Record Updates

Last Update Posted (Actual)

August 2, 2022

Last Update Submitted That Met QC Criteria

July 29, 2022

Last Verified

July 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • CPETPH

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Pulmonary Hypertension

Clinical Trials on balloon pulmonary angioplasty

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Qatar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe