- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02455466
Altered PSA Test Due to Possible Suspected Heterophilic Antibodies
May 29, 2017 updated by: University of Zurich
The purpose of this study is to investigate if clinically non explainable high or low Prostate-specific antigen (PSA) levels are associated with heterophilic antibodies in the serum of participants.
The investigators will examine if heterophilic antibodies are the reasons of altered PSA levels.
Study Overview
Status
Terminated
Conditions
Study Type
Observational
Enrollment (Actual)
50
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Zürich, Switzerland, 8091
- University Hospital Zurich
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
40 years to 90 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Male
Sampling Method
Non-Probability Sample
Study Population
Male, where a PSA measurement is planned
Description
Inclusion Criteria:
- Male, with a a clinically high or low unexplainable PSA measurement
- Age between 40 and 90 years
- Written informed consent
Exclusion Criteria:
- Female
- No PSA measurement available or planned
- Age over 90 or under 40 years
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Presence of heterophilic antibodies in the serum of participants
Time Frame: 1.5 years
|
Heterophilic antibodies will be measured in the Blood serum of participants by sandwich Elisa assay
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1.5 years
|
Altered PSA levels due to the Presence of Heterophilic antibodies
Time Frame: 1.5 years
|
If heterophilic antibodies were present in the serum of the participant, another PSA test will be ran after absorbance of heterophilic antibodies to investigate whether PSA levels are changed without the presence of heterophilic antibodies
|
1.5 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 1, 2015
Primary Completion (Actual)
December 31, 2016
Study Completion (Actual)
December 31, 2016
Study Registration Dates
First Submitted
May 11, 2015
First Submitted That Met QC Criteria
May 26, 2015
First Posted (Estimate)
May 27, 2015
Study Record Updates
Last Update Posted (Actual)
May 31, 2017
Last Update Submitted That Met QC Criteria
May 29, 2017
Last Verified
May 1, 2017
More Information
Terms related to this study
Other Study ID Numbers
- 2014-0652
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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