Correlation of Arterial and Venous Lactate and Base Deficit Values

January 30, 2017 updated by: Joseph D. Tobias
The purpose of this study is to determine the correlation between pH, base deficit, and lactate values when comparing venous and arterial blood samples in the pediatric population.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Ohio
      • Columbus, Ohio, United States, 43205
        • Nationwide Children's Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Patients requiring arterial access and peripheral access. Additionally, patients with a central venous catheter would be included.

Description

Inclusion Criteria:

  • Patients requiring arterial access and peripheral access. Additionally, patients with a central venous catheter would be included.

Exclusion Criteria:

  • Patients who not require arterial access.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Arterial blood sample
0.5 mL blood sample from arterial line which is clinically indicated
Device: bedside point-of-care device
A bedside point-of-care device is routinely used in the operating room to measure lactate, base deficit, and pH.
peripheral venous blood sample
0.5 mL blood sample drawn simultaneously with arterial sample from clinically indicated peripheral line
Device: bedside point-of-care device
A bedside point-of-care device is routinely used in the operating room to measure lactate, base deficit, and pH.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
lactate blood value
Time Frame: During surgery- approximately 15-20 minutes after induction in the operating room (OR)
blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the lactate value will be assessed by using a bedside point-of-care device, called i-stat.
During surgery- approximately 15-20 minutes after induction in the operating room (OR)
base deficit blood value
Time Frame: During surgery- approximately 15-20 minutes after induction in the operating room (OR)
blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the base deficit blood value will be assessed by using a bedside point-of-care device, called i-stat.
During surgery- approximately 15-20 minutes after induction in the operating room (OR)
pH blood value
Time Frame: During surgery- approximately 15-20 minutes after induction in the operating room (OR)
blood will be drawn from peripheral venous line, arterial line, and/or central venous line then pH blood value will be assessed by using a bedside point-of-care device, called i-stat.
During surgery- approximately 15-20 minutes after induction in the operating room (OR)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Joseph D. Tobias

Investigators

  • Principal Investigator: Joseph Tobias, Nationwide Children's Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2015

Primary Completion (Actual)

December 1, 2016

Study Completion (Actual)

December 1, 2016

Study Registration Dates

First Submitted

August 17, 2016

First Submitted That Met QC Criteria

August 30, 2016

First Posted (Estimate)

September 5, 2016

Study Record Updates

Last Update Posted (Estimate)

January 31, 2017

Last Update Submitted That Met QC Criteria

January 30, 2017

Last Verified

January 1, 2017

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • IRB15-00793

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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