Central Venous Catheter Care Training for Pediatric Oncology Nurses

January 7, 2026 updated by: Emine I Yıldız, Fenerbahce University

Training in Central Venous Catheter Care: Effects on Knowledge and Infection Prevention Behaviors of Pediatric Oncology Nurses

The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections. This study was designed to evaluate the effect of training on central venous catheter care (CVCC), provided to nurses caring for pediatric oncology patients, on their knowledge level and infection prevention behaviors. The study aims to determine the effectiveness of an educational program intended to enhance nurses' knowledge and practical skills in preventing CVC-related infections, thereby contributing to evidence-based practices that improve patient safety.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Quasi-experimental, pre-test/post-test desing with a control group. Central catheters are frequently used in hematology and oncology clinics. They are invasive devices employed in hospitalized patients for fluid therapy, drug administration, blood transfusions, total parenteral nutrition, and hemodynamic monitoring. In addition to enabling the effective continuation of treatment, they provide patients with a more comfortable therapeutic experience.

Proper maintenance of catheters is crucial for treatment continuity. Despite their medical advantages, central venous catheters (CVCs) are associated with complications such as infection, hemorrhage, and thrombosis. When central venous catheterization and catheter care are performed by inexperienced personnel or teams, the risk of catheter colonization and infection increases. Furthermore, if the catheter remains in place for more than five days, the risk of infection is eight times higher in groups using gauze dressings and microporous tape.

CVC-related infection is a significant cause of morbidity and mortality in immunocompromised children and adults, with infection-related mortality estimated between 12% and 25%. Recent studies have demonstrated that standardization of aseptic techniques and the provision of regular training reduce the risk of infection, while catheter insertion and maintenance by inexperienced personnel increase the likelihood of colonization or infection.

Nurses are key personnel both during central venous catheter insertion and in ensuring catheter care is maintained with aseptic technique . Regular training of healthcare professionals responsible for catheter insertion and care, ensuring compliance with hand hygiene, and adopting maximum barrier precautions during insertion (use of sterile gloves, gown, sterile drape covering the insertion site, mask, and cap) are recommended. In addition, the use of >0.5% chlorhexidine-alcohol combinations for skin antisepsis, routine use of chlorhexidine/antiseptic-impregnated catheters, and chlorhexidine-impregnated dressings are advised.

There are various nursing care practices aimed at preventing CVC-associated infections. It has been recommended that healthcare professionals conduct high-level evidence clinical studies to evaluate the effectiveness of these practices on infection, develop clinical protocols that may serve as guidelines for CVC care, and monitor these protocols regularly. Many healthcare institutions provide not only initial training for newly employed staff but also refresher training for existing personnel. Since aseptic techniques are complex, nurses need to complement their education with practical training to strengthen their knowledge and skills. CVC-associated infections remain an important risk factor; however, with properly planned training, nurses' knowledge of current guidelines and their compliance with them should be periodically evaluated . Educational programs provided to nurses should be didactic, evidence-based, and structured with appropriate content and timing.

Nursing is an applied profession that requires meaningful integration of theoretical knowledge and practical skills. Therefore, this study was designed to evaluate the effect of theoretical and practical training on central venous catheter care, provided to nurses caring for pediatric oncology patients, on their knowledge level and infection prevention behaviors.

Study Type

Interventional

Enrollment (Estimated)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Provided care to a pediatric oncology patient at least once
  • Performed a procedure via a central venous catheter on a pediatric oncology patient
  • Voluntarily signed the informed consent form

Exclusion Criteria:

  • Not having previously performed a procedure via a central venous catheter

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Training Group
Participants in this arm will receive the central venous catheter care training program, including theoretical education, video demonstration, and hansd-on practice.
Other: CVC Care Training
The intervention consists of an educational training program including a PowerPoint presentation, training video, and hands-on practice with a mannequin. Data collection tools include the Sociodemographic Information Form, the Evidence-Based Guidelines Knowledge Test, and the Nurses' Observation Questionnaire on Infection Control and Prevention.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Infection Prevention Behaviors
Time Frame: During the 4 weeks before training (baseline) and during the 4 weeks after completion of the training program
Measured by the Nurses' Observation Checklist for Infection Control and Prevention (19 items). Higher scores indicate better infection prevention practices. Nurses will be observed before and after the training.
During the 4 weeks before training (baseline) and during the 4 weeks after completion of the training program
Change in Knowledge Level of Nurses
Time Frame: At baseline (pre-training) and on the same day immediately after completion of the training
Measured by the Evidence-Based Guidelines Knowledge Test (10 questions). Higher scores indicate greater knowledge. Nurses will complete the test before and after the training.
At baseline (pre-training) and on the same day immediately after completion of the training

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Post-Training Observation of Infection Prevention Behaviors
Time Frame: At 4 weeks after completion of the training program
Nurses will be observed in their clinical practice environment after completing the training program. Observations will be conducted by the principal investigator and an independent observer using the Nurses' Observation Checklist for Infection Control and Prevention (19 items). Higher scores indicate better infection prevention practices. Scores will be recorded as post-training results.
At 4 weeks after completion of the training program

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Fenerbahce University

Collaborators

Acibadem Maslak Hospital

Investigators

  • Study Director: Yagmur Sancı, Assistant Professor, Fenerbahçe University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

January 22, 2026

Primary Completion (Estimated)

May 22, 2026

Study Completion (Estimated)

June 22, 2026

Study Registration Dates

First Submitted

September 12, 2025

First Submitted That Met QC Criteria

January 7, 2026

First Posted (Actual)

January 15, 2026

Study Record Updates

Last Update Posted (Actual)

January 15, 2026

Last Update Submitted That Met QC Criteria

January 7, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FBU-YILDIZ-001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

De-identified individual participant data (IPD) will be available from the corresponding author upon reasonable request for academic and scientific research purposes.

IPD Sharing Time Frame

6 months after publication-5 years

IPD Sharing Access Criteria

De-identified IPD will be available to qualified researchers for academic and scientific purposes. Access will be granted upon reasonable request to the corresponding author, subject to approval of a research proposal and compliance with institutional ethical standards.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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