Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (COVD)

January 5, 2017 updated by: University Hospital, Strasbourg, France

Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (COVD)

Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.

The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction.

A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Strasbourg, France, 67091
        • Service Réanimation chirurgicale cardio-vasculaire - NHC

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

The study population consisted of patients in immediate postoperative period of cardiac surgery, hospitalized in surgical intensive care department

Description

Inclusion Criteria:

  • Age: all major patient
  • Gender: both
  • Subject has signed an informed consent
  • IRA KDIGO stage 1 or urine output <0.5 mL / kg / h for at least 6 hours / elevation creat> 26.5μmol / L
  • Patient in sinus rhythm at the time of the ultrasound measurements
  • No diuretic since intervention
  • Absence of circulatory failure (low doses of catecholamines tolerated)
  • Extubated: absence of mechanical ventilation

Exclusion Criteria:

  • Chronic heart failure right
  • Chronic renal failure (GFR <60)
  • Usual treatment with high dose diuretics (furosemide> 40mg / day)
  • Endocarditis
  • Emergency surgery (aortic dissection, emergency bypass surgery) / heart surgery D / redux
  • Circulatory Support
  • ACFA / electro-paced rhythm
  • Inability to give informed about information (subject in emergencies, understanding of the subject of difficulty, ...)
  • Topic under judicial protection
  • Topic guardianship or curatorship
  • Pregnancy (women of childbearing age)
  • Breastfeeding

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Quantification of sonographic markers of right ventricular
Time Frame: 1 hour after cardiac surgery
1 hour after cardiac surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Strasbourg, France

Investigators

  • Study Director: Paul-Michel MERTES, MD, PhD, University Hospital, Strasbourg, france

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2017

Primary Completion (Anticipated)

January 1, 2018

Study Completion (Anticipated)

January 1, 2018

Study Registration Dates

First Submitted

August 30, 2016

First Submitted That Met QC Criteria

January 5, 2017

First Posted (Estimate)

January 6, 2017

Study Record Updates

Last Update Posted (Estimate)

January 6, 2017

Last Update Submitted That Met QC Criteria

January 5, 2017

Last Verified

August 1, 2016

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 6296

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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