Prediction of Postoperative Pain by Injection Pain of Propofol

January 13, 2017 updated by: Go Un Roh, Ajou University School of Medicine

Postoperative pain is a significant postoperative problem and it could be persistent if proper management is not provided. However, each patient shows different intensity of pain and different sensitivity to analgesics even if they underwent same procedures. Therefore, it would be useful to find the way to predict the postoperative pain sensitivity.

Propofol, a popular anesthetic agent, induces pain during injection, which can not completely prevented by opioid or lidocaine in some patients. This is considered to be related to patient's pain sensitivity and it might be associated with postoperative pain sensitivity.

Therefore, the relation of propofol injection pain and postoperative pain intensity will be explored.

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

70

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 60 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Female

Sampling Method

Probability Sample

Study Population

Patients scheduled for laparoscopic cholecystectomy will be included.

Description

Inclusion Criteria:

  • America Society of Anesthesiologists class I-II
  • Laparoscopic cholecystectomy

Exclusion Criteria:

  • Pregnancy
  • Illiteracy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
postoperative pain intensity_1
Time Frame: 10 min after postanesthesia care unit admission
Postoperative pain will be evaluated with verbal numeric scale (0-10)
10 min after postanesthesia care unit admission

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
postoperative pain intensity_2
Time Frame: 20 min after postanesthesia care unit admission
Postoperative pain will be evaluated with verbal numeric scale (0-10)
20 min after postanesthesia care unit admission
postoperative pain intensity_3
Time Frame: 30 min after postanesthesia care unit admission
Postoperative pain will be evaluated with verbal numeric scale (0-10)
30 min after postanesthesia care unit admission
postoperative pain intensity_4
Time Frame: 4 hours after operation
Postoperative pain will be evaluated with verbal numeric scale (0-10)
4 hours after operation
postoperative pain intensity_8
Time Frame: 8 hours after operation
Postoperative pain will be evaluated with verbal numeric scale (0-10)
8 hours after operation
postoperative pain intensity_12
Time Frame: 12 hours after operation
Postoperative pain will be evaluated with verbal numeric scale (0-10)
12 hours after operation
postoperative pain intensity_24
Time Frame: 24 hours after operation
Postoperative pain will be evaluated with verbal numeric scale (0-10)
24 hours after operation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ajou University School of Medicine

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2017

Primary Completion (Anticipated)

December 1, 2017

Study Completion (Anticipated)

December 1, 2017

Study Registration Dates

First Submitted

January 12, 2017

First Submitted That Met QC Criteria

January 13, 2017

First Posted (Estimate)

January 16, 2017

Study Record Updates

Last Update Posted (Estimate)

January 16, 2017

Last Update Submitted That Met QC Criteria

January 13, 2017

Last Verified

January 1, 2017

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AJIRB-MED-OBS-16-48

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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