- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03093623
The Effect of Physical Activity and Abstain From Smoking on the Precancerous Lesion
The Effect of Physical Activity and Abstain From Smoking on the Regression of Precancerous Lesion.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Yu-Wen Su, Bs
- Phone Number: 0917562397
- Email: m432104011@tmu.edu.tw
Study Contact Backup
- Name: Hsiu-Ting Tsai, Phd
- Phone Number: 6337 02-2736-1661
- Email: hsiuting@tmu.edu.tw
Study Locations
-
-
-
Taipei, Taiwan, 110
- Recruiting
- Taipei Medical University
-
Contact:
- Wen-Chi Liu, MSc
- Phone Number: 1300 02-227372181
- Email: 116085@tmuh.org.tw
-
Principal Investigator:
- Hsiu-Ting Tsai, Phd
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Patients with precancerous neoplasia
- between 20 to 70 years
Exclusion Criteria:
- Patients with server heart disease or other cancer.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: PREVENTION
- Allocation: RANDOMIZED
- Interventional Model: CROSSOVER
- Masking: SINGLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: Physical activity
In physical activity experimental group, trained study nurses will interview with patients,give health education,teach how to use and record the Activity meter.Professionals will calculate Metabolic Equivalent of Task(MET) with formula weekly.MET = (intensity level 9 points * time of each exercise (hours) * Number of times per week + moderate level 5 points * time per activity (hours) * number of times per week + low level 3 points * time per activity (hours) * number of times per week),investigators hope patients in the first month MET can reach (3.75-7.49
MET-h/ week), and reach moderate or more than moderate activity (>= 7.5-16.49
MET-h/ week) at the starting of second month for at least one year.
|
In physical activity experimental group, trained study nurses will interview with patients,give health education,teach how to use and record the Activity meter.Professionals will calculate Metabolic Equivalent of Task(MET) with formula weekly.MET = (intensity level 9 points * time of each exercise (hours) * Number of times per week + moderate level 5 points * time per activity (hours) * number of times per week + low level 3 points * time per activity (hours) * number of times per week),investigators hope patients in the first month MET can reach (3.75-7.49
MET-h/ week), and reach moderate or more than moderate activity (>= 7.5-16.49
MET-h/ week) at the starting of second month for at least one year.
|
NO_INTERVENTION: Non-Physical activity
the non-physical activity group,investigators do not give them any physical interventions
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The effect of physical activity and abstain from smoking on the regression of precancerous
Time Frame: 2 years
|
To estimate the effect of moderate physical activity and abstain from smoking can strengthen the innate immune system,adaptive human immune system and can help regression of Cervical intraepithelial neoplasia among patients with cervical cancer. Using a composite outcome measure consisting of questionnaire,blood counts,plasma and DNA. blood counts :white blood cells,hemoglobin,red blood cells,platelets,Neutrophil,Lymphocyte,Monocyte,Eosinophil,Basophil,CD-4,CD-8,NK-cell,B-cell. plasma:lL-1,IL-2,IL-4,IL-5,IL,6,LI-8,IL-10,IL-13,TNF-r |
2 years
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Hsiu-Ting Tsai, Phd, Taipei Medical University
Publications and helpful links
General Publications
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- http://www.cdc.gov/physicalactivity.
- Department of Health: Republic of China: ''Health Promotion Administration, Ministry of Health and Welfare'' Department of Health. Taipei 2013
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Study record dates
Study Major Dates
Study Start
Primary Completion (ANTICIPATED)
Study Completion (ANTICIPATED)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ACTUAL)
Study Record Updates
Last Update Posted (ACTUAL)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- TMU-JIRB:201410013
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
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