Post - Hospital Syndrome: Profile of Functional Status by Malnutrition

January 27, 2020 updated by: Kristina Norman, Charite University, Berlin, Germany

Post-Hospital Syndrome: Evaluation of Functional Status in Malnourished, Geriatric Patients at Hospital Discharge

Malnutrition is common problem in hospitalized geriatrics at discharge. Malnutrition is a high risk for functional limitations, impaired muscle strength and reduced quality of life.

Study Overview

Status

Unknown

Conditions

Detailed Description

The majority of geriatric hospitalized patients are at high risk for malnutrition at discharge, which has negative impact on post-hospital outcomes. In a cross-sectional analysis in malnourished, geriatric patients we will evaluate frailty-status and functional status using objective and subjective methods at hospital discharge. Moreover, we will investigate the association between nutritional Status and frailty, sarcopenia, quality of life and fatigue.

Study Type

Observational

Enrollment (Anticipated)

200

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Berlin, Germany
        • Recruiting
        • Charite University, Berlin, Germany
        • Contact:
          • Kristina Norman, PD Dr.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Study participants are assessed upon discharge from the hospital. Only malnourished patients were analyzed.

Description

Inclusion Criteria:

  • Age ≥ 60 years
  • Informed written consent
  • Existing or risk of malnutrition
  • Normal cognitive status according to Mini-Mental State Examination (MMSE ≥ 24 points)
  • Life expectancy of > 3 months according to treating doctor

Exclusion Criteria:

  • Age < 60 years
  • Lack of informed written consent
  • No risk of malnutrition
  • Low cognitive status according to Mini-Mental State Examination (MMSE < 24 points)
  • Life expectancy of < 3 months according to treating doctor

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Malnourished
malnourished, geriatrics patients at hospital discharge

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Functional Parameter: gait speed
Time Frame: Baseline (hospital discharge)
gait analysis
Baseline (hospital discharge)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Functional Parameter: timed up & go (TUG) time
Time Frame: Baseline (hospital discharge)
timed up & go (TUG) test
Baseline (hospital discharge)
Functional Parameter: stair climbing time
Time Frame: Baseline (hospital discharge)
stair climbing test
Baseline (hospital discharge)
Functional Parameter: Peak expiratory flow rate
Time Frame: Baseline (hospital discharge)
peak flow meters scale
Baseline (hospital discharge)
Strength Parameter: Hand grip strength
Time Frame: Baseline (hospital discharge)
Hand grip strength measurement
Baseline (hospital discharge)
Strength Parameter: Knee extension strength
Time Frame: Baseline (hospital discharge)
Knee extension strength measurement
Baseline (hospital discharge)
Index of quality of life
Time Frame: Baseline (hospital discharge)
validated questionnaire
Baseline (hospital discharge)
Body composition
Time Frame: Baseline (hospital discharge)
bioelectric impedance Analysis
Baseline (hospital discharge)
Frailty-Status
Time Frame: Baseline (hospital discharge)
Fried criteria
Baseline (hospital discharge)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Charite University, Berlin, Germany

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 31, 2017

Primary Completion (Anticipated)

April 30, 2021

Study Completion (Anticipated)

June 30, 2021

Study Registration Dates

First Submitted

April 12, 2017

First Submitted That Met QC Criteria

April 20, 2017

First Posted (Actual)

April 24, 2017

Study Record Updates

Last Update Posted (Actual)

January 28, 2020

Last Update Submitted That Met QC Criteria

January 27, 2020

Last Verified

January 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • POSTHOSP

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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