Sport and Self Esteem in Patients Living With HIV

Assessment of Self-esteem According to the Practice of a Sport Activity in a Population of Adults Living With HIV

Adapted athletic activity has shown benefits in patients with certain chronic diseases, including improving fatigue and pain in patients with cancer, and improving the symptoms of severe depression.

Among Patients Living with Human Immunodeficiency Virus (PLHIV), sport appears to be less common than for people who do not live with HIV. In fact, 44% of PLHIV in a Swiss cohort (10,500 patients) were inactive in 2014, whereas this percentage was 26% in the general population in Switzerland. We did not find any French data on the prevalence of sports activity among PLHIV.

The benefits of sport in PLHIV are numerous: meta-analyzes on interventional studies of aerobic and resistance exercises show a significant improvement in maximum oxygen consumption, muscle strength, percentage of body fat, quality of life and symptoms of depression. An improvement in cognitive function was noted in a randomized study. An Iranian randomized study of 2017 showed an improvement in the CD4 count, after 8 weeks of resistive exercise, but two meta-analyzes of 2016 and 2017 did not find a significant change in CD4 or viral load with physical exercise.

On the other hand, several studies have shown that sports practice improves self-esteem. In addition, an Australian randomized study in 2006 showed an improvement in self-efficacy in PLHIVs after a six-month exercise (aerobic and resistance) program. Furthermore, self-esteem (defined as positive self-esteem) is a factor facilitating adherence to antiretroviral therapy.

The objective of this descriptive study is to evaluate the prevalence of sports activity in a French adult population infected with HIV and to seek an association with self-esteem. In addition, the investigators will look for an association between sport and fatigue, pain, sleep, lymphocyte T CD4 cell levels, viral load.

Study Overview

• Status: Completed
• Conditions: HIV Seropositivity
• Intervention / Treatment: Behavioral: Sports activity

• Study Type: Observational
• Enrollment (Actual): 1169

Contacts and Locations

Study Locations

• France
  • Le Mans, France, 72 000
    • Centre Hospitalier Le Mans

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of all HIV-infected patients followed in one of the COREVIH centers of Pays de la Loire participating in this study. Participation in the study will be offered to patients during a usual visit as part of the follow-up of their pathology. The annual number of patients in 2017 being 4300, it is estimated that the number of patients included will be between 1000 and 2000 over 6 months of inclusion with a response rate of at least 50%.

Description

Inclusion Criteria:

• patient with HIV
• aged over 18
• Patient followed by a physician in one of the participating centers of the Regional coordination of the fight against HIV infection (COREVIH) Pays de la Loire

Exclusion Criteria:

• Refusal or unability to answer the self-questionnaire.
• Patient Under guardianship

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Assessment of self-esteem according to the sport activity of PLHIV	Prevalence of self-esteem (Rosenberg questionnaire) among PLHIV, according to sport activity	six months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Description of the sporting activity of an adult HIV population	Number and frequency of characteristics related to sports activity	Six months
Description of factors associated with sports activity: fatigue	Prevalence of fatigue symptoms	Six months
Description of factors associated with sports activity: pain	Prevalence of pain symptoms	Six months
Description of factors associated with sports activity: sleep	Prevalence of sleep disorders	Six months
Search for a correlation between physical activity and HIV activity	Measure of the correlation between the measured physical activity and CD4 levels and HIV load.	6 months

Collaborators and Investigators

• Sponsor: Centre Hospitalier le Mans
• Collaborators: University Hospital, Angers; Nantes University Hospital; Hospital, La Roche sur Yon; Centre Hospitalier de Cholet; COordination REgionale de lutte contre les IST et le VIH (COREVIH) des Pays de la Loire; Hospital, Saint Nazaire
• Investigators: Principal Investigator: Lucia Perez, MD, CH Le mans

Study record dates

Study Major Dates

• Study Start (ACTUAL): February 1, 2019
• Primary Completion (ACTUAL): December 31, 2019
• Study Completion (ACTUAL): December 31, 2019

Study Registration Dates

• First Submitted: April 16, 2019
• First Submitted That Met QC Criteria: April 16, 2019
• First Posted (ACTUAL): April 19, 2019

Study Record Updates

• Last Update Posted (ACTUAL): March 9, 2022
• Last Update Submitted That Met QC Criteria: March 8, 2022
• Last Verified: March 1, 2022

More Information

Terms related to this study

• Keywords: HIV; Self Esteem; Sport
• Additional Relevant MeSH Terms: RNA Virus Infections; Virus Diseases; Infections; Blood-Borne Infections; Communicable Diseases; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; Immunologic Deficiency Syndromes; Immune System Diseases; HIV Infections; HIV Seropositivity
• Other Study ID Numbers: CHM-2018-S10/002

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No