Fetal Myocardial Performance Index in Diabetic Pregnancies

Fetal Myocardial Performance Index in Diabetic Pregnancies

Sponsors

Lead sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Source Kanuni Sultan Suleyman Training and Research Hospital
Brief Summary

The myocardial tissue is the most likely structure affected by hyperglycemia. The myocardial performance index (MPI) is a pulsed wave Doppler-derived index of global myocardial function. It is defined as the sum of the isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) divided by the ejection time (ET) The fetal right heart contributes more to the cardiac output than the left heart; therefore, it is important to assess the right ventricular function. The investigators will measure right ventricular MPI in diabetic and normal pregnancies.

Detailed Description

Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy, with an overall prevalence of 3-7 % during pregnancy. The myocardial tissue is the most likely structure affected by hyperglycemia. The myocardial performance index (MPI) is a pulsed wave Doppler-derived index of global myocardial function. It is defined as the sum of the isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) divided by the ejection time (ET) The fetal right heart contributes more to the cardiac output than the left heart; therefore, it is important to assess the right ventricular function. The investigators will measure right ventricular MPI in diabetic and normal pregnancies.

Overall Status Completed
Start Date August 1, 2018
Completion Date March 31, 2019
Primary Completion Date March 31, 2019
Study Type Observational
Primary Outcome
Measure Time Frame
ultrasonographic myocardial performance index values during procedure
Enrollment 130
Condition
Intervention

Intervention type: Other

Intervention name: myocardial performance index

Description: fetal right ventricular myocardial performance index measured with tissue doppler

Eligibility

Sampling method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- 18-40 years old pregnant women

Exclusion Criteria:

- fetal cardiac anomalies

- multiple gestations

Gender: Female

Minimum age: 18 Years

Maximum age: 40 Years

Location
facility Kanuni SSRTH
Location Countries

Turkey

Verification Date

April 2019

Responsible Party

Responsible party type: Principal Investigator

Investigator affiliation: Kanuni Sultan Suleyman Training and Research Hospital

Investigator full name: Berna Aslan Cetin

Investigator title: Md, ObGYN, Principal Investigator

Has Expanded Access No
Condition Browse
Arm Group

Arm group label: Diabetic pregnancies

Description: Pregnant women with pregestational or gestational diabetes mellitus

Arm group label: non-diabetic pregnancies

Description: Pregnant women without pregestational or gestational diabetes mellitus

Patient Data No
Study Design Info

Observational model: Case-Control

Time perspective: Prospective

Source: ClinicalTrials.gov