Evaluating the Prevalence and Implications of Obstructive Sleep Apnea Among Somali-Americans: A Translational Research Study
Obstructive Sleep Apnea Among Somali-Americans
Lead sponsor: Mayo Clinic
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences. The investigators will compare Somali patients with known obstructive sleep apnea (OSA) to individuals without OSA, and to individuals of other ethnic/racial origins to determine the risk factors (genetic and/or physiologic) associated with developing cardiovascular diseases. This will help the investigators to understand the unique sleep pathology of individuals of African descent.
Participants can be healthy volunteers or volunteers diagnosed with obstructive sleep apnea. All patients may undergo a sleep study (i.e. hospital or home-based), physical examination, questionnaires, blood and urine samples, ultrasound scan of the heart and brachial artery in the arm, CT scan, DEXA scan, paced breathing test, cardiopulmonary test and chemo-sensitivity test.
|Start Date||October 25, 2019|
|Completion Date||December 31, 2028|
|Primary Completion Date||December 31, 2028|
Sampling method: Non-Probability Sample
Inclusion Criteria: - Self-identify as Somali, African, Asian, and European descent. - Adult males and females who are older than 18 years of age. Exclusion Criteria: - Minors under 18 years or adults over 100 years - Positive pregnancy
- Self-identify as Somali, African, Asian, and European descent.
- Adult males and females who are older than 18 years of age.
- Minors under 18 years or adults over 100 years
- Positive pregnancy
Minimum age: 18 Years
Maximum age: N/A
Healthy volunteers: Accepts Healthy Volunteers
Last name: Essa Mohamed, PhD
Email: [email protected]
Responsible party type: Principal Investigator
Investigator affiliation: Mayo Clinic
Investigator full name: Virend Somers
Investigator title: Principal Investigator
|Has Expanded Access||No|
Arm group label: Somali Descent
Description: Study participants who are of Somali origin.
Arm group label: Non-Somali Descent
Description: Study participants who are not of Somali origin.
|Study Design Info||
Observational model: Cohort
Time perspective: Prospective