Cataract Surgery In Patients With Advanced Age

Outcomes of Cataract Surgeries in Patients With Advanced Age

This study evaluates and compares clinical outcomes of < 85 and ≥ 85 year old patients who underwent cataract surgeries.

Study Overview

• Status: Completed
• Conditions: Cataract Senile
• Intervention / Treatment: Procedure: Cataract Surgery

Detailed Description

The medical records of patients who were underwent cataract surgery between January 2014 and October 2017 were investigated retrospectively and patients 65 years and older were recruited. Two groups were made according to age: group1 composed of patients age range between 65 and 85 years and group 2 composed of patients 85 years and older. Gender, presence of diabetes mellitus (DM), hypertension (HT), drug use were noted.

The results of best corrected visual acuity (BCVA) converted to LogMar, intraocular pressure (IOP) before and 3 months after operation, biomicroscopic and fundus examinations were investigated.

Additional ocular diseases such as glaucoma, age related macular degeneration (AMD), pseudoexfoliation syndrome, retinopathies and maculopathies related to systemic diseases were noted. Pupil dilation properties were also noted as poor, mid or full pupil dilation.

Cataract surgery techniques such as phacoemulsification, extra- and intracapsular lens extractions, peroperative complications, intracameral drug use were investigated.

these aforementioned outcomes evaluated and compared between groups.

• Study Type: Observational
• Enrollment (Actual): 152

Contacts and Locations

Study Locations

• Turkey
  • Sakarya, Turkey
    • Sakarya University Ophthalmology Department

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years to 95 years (Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

patients aged 65 years and older who underwent cataract surgery

Description

Inclusion Criteria:

• patients aged 65 years and older patients who underwent cataract surgery

Exclusion Criteria:

• patients aged below 65 years who underwent cataract surgery

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Group 1, patients aged 85 years and older; 75 eyes of 75 patients (39 female, 36 male) Mean age: 86,8 ± 1,8 years	Procedure: Cataract Surgery; Cataract surgery was performed by using phacoemulsification technique, routinely. But other techniques for instance extra or intracapsular cataract extraction (ECCE, ICCE) techniques were performed when needed. Phacoemulsification technique was performed by 2 experienced surgeon (G.A. and E.C.) under topical anesthesia, thorough limbal incision. Foldable single piece hydrophobic acrylic intraocular lens (IOL) was inserted in the bag. In the presence of complications related to anterior or posterior capsules, 3 pieces IOL was preferred. When ECCE technique was chosen, single piece polymethyl methacrylate IOL was inserted.
Group 2, patients aged 65 and 85 years; 77 eyes of 77 patients (34 female, 43 male) Mean age:73,3 ± 5,2 years	Procedure: Cataract Surgery; Cataract surgery was performed by using phacoemulsification technique, routinely. But other techniques for instance extra or intracapsular cataract extraction (ECCE, ICCE) techniques were performed when needed. Phacoemulsification technique was performed by 2 experienced surgeon (G.A. and E.C.) under topical anesthesia, thorough limbal incision. Foldable single piece hydrophobic acrylic intraocular lens (IOL) was inserted in the bag. In the presence of complications related to anterior or posterior capsules, 3 pieces IOL was preferred. When ECCE technique was chosen, single piece polymethyl methacrylate IOL was inserted.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Best corrected visual acuity	Best corrected visual acuity converted to LogMar	Before cataract surgery
Best corrected visual acuity	Best corrected visual acuity converted to LogMar	three months after cataract surgery

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
presence of Diabetes Mellitus	number of participants who have diabetes mellitus	Baseline (Before cataract surgery)
presence of essential hypertension	number of participants who have essential hypertension	before cataract surgery
oral acetylsalicylic acid use	number of participants who have a history of acetylsalicylic acid use	before cataract surgery
oral flomax use	number of participants who have a history of oral flomax use	before cataract surgery
presence of age related macular degeneration	number of participants who have age related macular degeneration	Baseline (Before cataract surgery)
presence of glaucoma	number of participants who have glaucoma	before cataract surgery
presence of pseudoexfoliation	number of participants who have pseudoexfoliation	before cataract surgery
presence of poor pupil dilation	number of participants who have poor pupil dilation	During cataract surgery
presence of zonule deficiency	number of participants who have zonule deficiency	During cataract surgery
Cataract types in patients who underwent cataract surgery	number of participants who have nuclear, posterior subcapsular, corticonuclear, mature, nigra, traumatic cataract	Baseline (Before cataract surgery)
measurement of effective phacoemulsification time	measurement of effective phacoemulsification time in participants who underwent cataract surgery	During cataract surgery
presence of posterior capsule rupture	participants who had posterior capsule rupture during surgery	During cataract surgery
anterior vitrectomy	number of participants who needed anterior vitrectomy during cataract surgery	during surgery
presence of aphakia	number of participants who left aphakic after cataract surgery	3 months after cataract surgery
intracameral adrenalin use	number of participants who needed intracameral adrenalin use	during surgery

Collaborators and Investigators

• Sponsor: Sakarya University
• Investigators: Principal Investigator: Burcin Cakir, MD, Sakarya University

Publications and helpful links

General Publications

• Syam PP, Eleftheriadis H, Casswell AG, Brittain GP, McLeod BK, Liu CS. Clinical outcome following cataract surgery in very elderly patients. Eye (Lond). 2004 Jan;18(1):59-62. doi: 10.1038/sj.eye.6700521.

Helpful Links

• Sussex Eye Hospital, Brighton, United Kingdom

Study record dates

Study Major Dates

• Study Start (Actual): October 2, 2017
• Primary Completion (Actual): December 2, 2017
• Study Completion (Actual): February 25, 2018

Study Registration Dates

• First Submitted: October 13, 2019
• First Submitted That Met QC Criteria: October 24, 2019
• First Posted (Actual): October 25, 2019

Study Record Updates

• Last Update Posted (Actual): October 25, 2019
• Last Update Submitted That Met QC Criteria: October 24, 2019
• Last Verified: October 1, 2019

More Information

Terms related to this study

• Keywords: cataract surgery; advanced age; geriatry
• Additional Relevant MeSH Terms: Eye Diseases; Lens Diseases; Cataract
• Other Study ID Numbers: Sakarya Ophthalmology

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Study Data/Documents

1. Clinical Study Report

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No