The Effect of Black Currant on Postprandial Glucose Metabolism (MAQUA)

September 3, 2020 updated by: University of Eastern Finland
The study examines the effect of black currant on glucose and insulin concentrations after a meal. In addition, the cytokine and free fatty acids levels are of interest.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The study examines the effect of black currant on glucose and insulin concentrations after a meal.

Healthy (n= 30) volunteers are recruited to participate in four consecutive visits in the research laboratory, when four meals are served in randomised order. Meals are: black currant puree, black currant and quinoa based snack, quinoa base and liquid containing glucose, fructose and sucrose. The meals contain the same amount of carbohydrates.

In addition to glucose and insulin concentration, cytokine and free fatty acid concentrations are measured after each meal.

Study Type

Interventional

Enrollment (Actual)

26

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Finland
      • Kuopio, Finland, 70211
        • University of Eastern Finland

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

25 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • age: 25-65 years
  • BMI: 20-28 kg/m2
  • Perceived health status: Good

Exclusion Criteria:

  • fasting glucose: > 7.0 mmol/l
  • LDL-cholesterol: > 3.0 mmol/l
  • total cholesterol: > 6.5 mmol/l
  • blood pressure : > 160/100 mmHg
  • weight change of > 5% during previous 6 months or active weightreduction
  • no serious chronic diseases
  • one exception of the exclusion criteria maybe accepted after the MD consideration

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Black currant puree
Other: Black currant

The effect of black currant puree will be compared with black currant-quinoa product, quinoa base and with liquid with glucose, fructose and sucrose

Experimental: Black currant and quinoa product

Active Comparator: Quinoa base Meal study comparing the effect of black currant puree with liquid with glucose, fructose and sucrose, black currant and quinoa product and quinoa base
Active Comparator: Black currant-quinoa product
Other: Black currant-quinoa product
The effect of black currant puree will be compared with black currant-quinoa product
Active Comparator: Quinoa base
Quinoa base is used for the black currant-quinoa product.
Other: Quinoa base
The effect of black currant puree will be compared with quinoa base
No Intervention: Liquid with glucose, fructose and sucrose

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Glucose concentration
Time Frame: 0 minutes until 180 minutes
Glucose concentration after meal
0 minutes until 180 minutes
Insulin concentration
Time Frame: 0 minutes until 180 minutes
Insulin concentration after meal
0 minutes until 180 minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Eastern Finland

Collaborators

Savonia University of Applied Sciences
Regional Development Company SavoGrow

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 15, 2019

Primary Completion (Actual)

February 28, 2020

Study Completion (Actual)

April 30, 2020

Study Registration Dates

First Submitted

November 1, 2019

First Submitted That Met QC Criteria

November 1, 2019

First Posted (Actual)

November 5, 2019

Study Record Updates

Last Update Posted (Actual)

September 4, 2020

Last Update Submitted That Met QC Criteria

September 3, 2020

Last Verified

September 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 894/2019

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

IPD Plan Description

Anonymised data maybe shared in the future.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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