EVALUER L'IMPACT PREDICTIF DU SCORE MEESSI POUR LA STRATIFICATION DU RISQUE DES PATIENTS ADMIS POUR INSUFFISANCE CARDIAQUE AIGUE DANS LES STRUCTURES D'URGENCES (ICA-MEESSI)

EVALUER L'IMPACT PREDICTIF DU SCORE MEESSI POUR LA STRATIFICATION DU RISQUE DES PATIENTS ADMIS POUR INSUFFISANCE CARDIAQUE AIGUE DANS LES STRUCTURES D'URGENCES (ICA-MEESSI)

Our primary purpose is to assess MEESSI score in predicting mortality and readmission of patients managed for acute heart failure (AHF) in Emergency Department.

European Society of Cardiology recommend risk stratification for patients with AHF. MEESSI score is not prospectively validated out of Spain.

Study Overview

• Status: Completed
• Conditions: Acurate Heart Failure
• Intervention / Treatment: Other: MEESSI score

• Study Type: Observational
• Enrollment (Actual): 367

Contacts and Locations

Study Locations

• France
  • Besançon, France, 25030
    • Hopital Jean Minjoz
  • Cahors, France, 46005
    • Centre Hospitalier Jean Rougie
  • Colmar, France, 68000
    • Hopitaux Civils de Colmar
  • Haguenau, France, 67500
    • CH Haguenau
  • Montbrison, France, 42605
    • Centre Hospitalier Forez
  • Montpellier, France, 34295
    • CHU de Montpellier
  • Nancy, France, 54035
    • Chu de Nancy
  • Paris, France, 75013
    • CHU Pitié Salpétrière
  • Reims, France, 51100
    • CHU de Reims
  • Remiremont, France, 88200
    • Ch Remiremont
  • Sarreguemines, France, 57200
    • Hôpital Robert Pax
  • Strasbourg, France, 67091
    • Les Hôpitaux Universitaires de Strasbourg
  • Toulouse, France, 31300
    • CHU Toulouse
  • Trévenans, France, 90400
    • Hôpital Nord Franche Comté

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patient admitted to emergencies with suspicion of ICA

Description

Inclusion Criteria:

• Major patient
• Patient admitted to emergencies with suspicion of ICA according to the clinical intuition of the emergency doctor after interrogation, clinical examination, biology and imaging
• Patient with health insurance
• Subject who accept to participate in the research

Exclusion Criteria:

• Patient who refuse to participate in the study
• Patient with coronary syndrome with ST segment elevation
• Other diagnosis of dyspnea
• Persons deprived of their freedom or under the protection of justice
• Persons under guardianship or curatorship
• Impossibility of giving the patient informed information
• Pregnant woman

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
patients with acurate heart failure	Other: MEESSI score; MEESSI score in predicting mortality and readmission of patients managed for acute heart failure (AHF) in Emergency Department.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
MEESSI score	Tscore to predict the patient's future in the month following management for ED ICA. That is to say the number of days alive outside the hospital in the month following an ICA episode.	30 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Re-admission rate	30-day re-admission rate compared between the 4 risk categories defined by the MEESSI score	30 days
Mortality rate	Mortality rate at 30 days compared between the 4 risk categories defined by the MEESSI score	30 days
Sensitivity	Sensitivity, specificity and ROC curve of the MEESSI score in relation to the composite criterion according to the 4 risk categories	30 days

Collaborators and Investigators

• Sponsor: University Hospital, Strasbourg, France

Study record dates

Study Major Dates

• Study Start (ACTUAL): December 19, 2020
• Primary Completion (ACTUAL): December 19, 2020
• Study Completion (ACTUAL): June 23, 2021

Study Registration Dates

• First Submitted: June 2, 2020
• First Submitted That Met QC Criteria: June 2, 2020
• First Posted (ACTUAL): June 5, 2020

Study Record Updates

• Last Update Posted (ACTUAL): October 8, 2021
• Last Update Submitted That Met QC Criteria: October 1, 2021
• Last Verified: October 1, 2021

More Information

Terms related to this study

• Keywords: emergency; caring
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Failure
• Other Study ID Numbers: 7880

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No