Plasma Amino Acid Response to Whey Protein Ingestion Following 28-days of Probiotic Supplementation

Plasma Amino Acid Response to Whey Protein Ingestion Following 28-days of Probiotic (Bacillus Subtilis DE111) Supplementation in Active Men and Women

Active males and females consumed a probiotic for 28-days. Before and after the intervention period, participants reported to the lab in a fasted state where they consumed 25 grams of whey protein. Following drink consumption, participants provided blood draws at 15-minute intervals. Blood samples were analyzed for amino acid concentrations.

Study Overview

• Status: Completed
• Conditions: Focus of Study is Amino Acid Appearace in Blood
• Intervention / Treatment: Dietary supplement: Placebo; Dietary supplement: Bacillus subtilis DE111

• Study Type: Interventional
• Enrollment (Actual): 22
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Tennessee
    • Nashville, Tennessee, United States, 37215
      • Jeremy Townsend

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 34 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• 18-34 years old Participants must have at least 1 year of resistance training experience.
• Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
• Are free of musculoskeletal injuries
• Are not taking medications that may interfere with study measurements

Exclusion Criteria:

• Taking any other nutritional supplement or performance enhancing drug.
• Any chronic illness that causes continuous medical care
• Taking any other nutritional supplement or performance enhancing drug.
• Any chronic illness that causes continuous medical care.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Probiotic; 1 x10-9 CFU Bacillus subtilis DE111 was consumed daily for 28-days	Dietary supplement: Bacillus subtilis DE111; 1 x10-9 CFU Bacillus subtilis DE111 probiotic
Placebo Comparator: Placebo; Maltodextrin placebo was consumed for 28-days	Dietary supplement: Placebo; Maltodextrin placebo

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Plasma Amino Acid response	We measured plasma amino acid concentrations before and after the 28-day intervention	28-days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Body Composition	Body Fat Percentage (%) will be monitored before and after the intervention via Bioelectical Impedance Analysis.	28-days

Collaborators and Investigators

• Sponsor: Lipscomb University
• Collaborators: Deerland Enzymes

Study record dates

Study Major Dates

• Study Start (Actual): January 8, 2018
• Primary Completion (Actual): May 3, 2018
• Study Completion (Actual): May 3, 2018

Study Registration Dates

• First Submitted: July 20, 2020
• First Submitted That Met QC Criteria: July 28, 2020
• First Posted (Actual): July 29, 2020

Study Record Updates

• Last Update Posted (Actual): July 29, 2020
• Last Update Submitted That Met QC Criteria: July 28, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Other Study ID Numbers: 01082018

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No